Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: wild-type ✕ Assay: subtype ✕ Clear

Multi-Transcriptomic Analysis Reveals That EREG-Driven TME Crosstalk Defines Anti-EGFR Response in Colorectal Cancer.

PMID 42043480 · PMC13115984 · Cancer medicine · 2026 · 8 claims · 8 setups

Full-text index only

EGFRI eligibility (defined by left-sidedness, RAS/BRAF wild-type, MSS) stratifies cancer cell transcriptomic characteristics more strongly than sidedness alone.

crc epcam+ aggregated cancer scrna-seq copy pseudobulk
Endothelial Adgrl2 Expression and Alternative Splicing Controls the Cerebrovasculature.

PMID 41876233 · PMC13108381 · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026 · 8 claims · 5 setups

Has reproduction · 75

Endothelial cell-specific deletion of Adgrl2 impairs cerebrovascular integrity in mice

wild-type cortex brain single-molecule single-cell immunohistochemistry
Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development.

PMID 16800721 · PMC1483910 · PLoS medicine · 2006 · 8 claims · 8 setups

Full-text index only

Multi-scale genomic similarities exist between four human lung cancer subtypes and the developing mouse lung, and these similarities are prognostically meaningful.

perfused lung microarray principal wilcoxon
Utilization of genomic signatures to identify phenotype-specific drugs.

PMID 19714244 · PMC2729377 · PloS one · 2009 · 8 claims · 8 setups

Full-text index only

A RAS pathway gene expression signature applied to NCI-60 cells identifies compounds selectively active against RAS-activated cells, including the MEK inhibitor Hypothemycin

nci-60 breast mda-mb-231 signature-drug gene signature
Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.

PMID 41651833 · PMC12988232 · Nature communications · 2026 · 8 claims · 8 setups

Full-text index only

IPA is consistently depleted in IBD/colitis patients and in murine colitis models relative to healthy controls

fecal c57bl germ-free mice quasi-targeted dss-induced tnbs-induced
Therapeutic manipulation and spatial quantification of the tumor microenvironment in colorectal cancer.

PMID 41907400 · PMC13018967 · iScience · 2026 · 8 claims · 8 setups

Full-text index only

Colorectal cancer fibroblast heterogeneity can be distilled into two overarching, transcriptomically distinct CAF populations marked by PDGFRA+ and ACTA2+ expression

crc colonic gemm scrna-seq multiplex bulk
Mosaic partial epidermal reprogramming remodels neighbors and niches to refine skin homeostasis and repair.

PMID 41617708 · PMC12960685 · Nature communications · 2026 · 8 claims · 8 setups

Full-text index only

A genetically engineered mouse model (Krt14-CreER; LSL-rtTA-EGFP; TetO-OSKM-mCherry, 'Epi-iOSKM') enables transient, reversible, mosaic OSKM expression in interfollicular epidermal cells without inducing pluripotency or teratoma risk

epidermis sorted epidermal ife immunostaining single-cell pseudotime
Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

PMID 41512855 · PMC12832054 · Neuron · 2026 · 8 claims · 8 setups

Full-text index only

Mucosal and muscularis glia are transcriptionally distinct populations, with mucosal glia resembling microglia and muscularis glia resembling satellite glia/astrocytes

ileum gfp+ intestinal intestine bulk scrna-seq bayesprism
Holliday junction recognition protein (HJURP) could reflect the clinical outcomes of lung adenocarcinoma patients, and impact the choice of precision therapy.

PMID 39649097 · PMC11621083 · Frontiers in genetics · 2024 · 7 claims · 8 setups

Full-text index only

HJURP is a significant prognostic biomarker in LUAD, with high expression associated with increased risk of overall survival death across four independent cohorts

tcga-luad best brain advanced bulk kaplan-meier pearson

Experiments

Multi-Transcriptomic Analysis Reveals That EREG-Driven TME Crosstalk Defines Anti-EGFR Response in Colorectal Cancer.

Endothelial Adgrl2 Expression and Alternative Splicing Controls the Cerebrovasculature.

Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development.

Utilization of genomic signatures to identify phenotype-specific drugs.

Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.

Therapeutic manipulation and spatial quantification of the tumor microenvironment in colorectal cancer.

Mosaic partial epidermal reprogramming remodels neighbors and niches to refine skin homeostasis and repair.

Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

Holliday junction recognition protein (HJURP) could reflect the clinical outcomes of lung adenocarcinoma patients, and impact the choice of precision therapy.