Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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FracFixR: a compositional statistical framework for absolute proportion estimation between fractions in RNA sequencing data.
PMID 41264734 · PMC12866640 · Bioinformatics (Oxford, England) · 2026 · 7 claims · 5 setups
FracFixR reconstructs original fraction proportions by modeling the compositional relationship between whole and fractionated RNA samples using non-negative least squares (NNLS) regression on selected transcripts
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Has reproduction · 50
RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations.
PMID 25236449 · PMC4174954 · Genetics · 2014 · 8 claims · 7 setups
Genetic variants distinguishing an individual genome from the reference cause read misalignment and biased transcript abundance estimates, and fine-tuning of alignment algorithms does not correct this problem.