Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 145

Assay: surface ✕ Clear

Functional diversity of HIV-1 envelope proteins expressed by contemporaneous plasma viruses.

PMID 18312646 · PMC2270869 · Retrovirology · 2008 · 8 claims · 7 setups

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Infectivity of recombinant viruses carrying different Env proteins from the same patient varies over an approximately 10-fold range, even among viruses with similar tropism.

env u373 mt4-r5 u373-r5 phylogenetic infectivity flow
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.

PMID 20035377 · PMC2929293 · Breast cancer research and treatment · 2010 · 8 claims · 8 setups

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Serine protease inhibitors (aprotinin, SBTI) cause morphological reversion of malignant T4-2 breast cancer cells in 3D culture, restoring acinar structure and basal polarity

hmt-3522 organotypic quantitative lentiviral
Reduced transcription of TCOF1 in adult cells of Treacher Collins syndrome patients.

PMID 20003452 · PMC2801500 · BMC medical genetics · 2009 · 8 claims · 5 setups

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TCOF1 transcript levels are significantly reduced (~18%) in leucocytes of TCS patients compared to controls

leucocytes mesenchymal leucocyte real-time direct flow
PCP consensus sequences of flaviviruses: correlating variance with vector competence and disease phenotype.

PMID 19969003 · PMC2822003 · Journal of molecular biology · 2010 · 7 claims · 7 setups

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PCP-consensus sequences of E protein show insertions/deletions that distinguish tick-borne, mosquito-borne, no-known-vector (NKV), and yellow fever virus (YFV) Flaviviruses

natural aligned ns3 denv sequence pcp-consensus physicochemical
Tissue compartment analysis for biomarker discovery by gene expression profiling.

PMID 19901995 · PMC2771357 · PloS one · 2009 · 8 claims · 5 setups

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TCA method quantifies the fractional volume of constitutive structures in a heterogeneous tissue sample by comparing marker mRNA levels in the whole sample to those in pure isolated structures

kidney pure serial rt-pcr sage histo-morphometry
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.

PMID 19890111 · PMC2787406 · The New England journal of medicine · 2009 · 8 claims · 8 setups

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Homozygous loss-of-function mutations in IL10RA or IL10RB cause severe early-onset enterocolitis

consanguineous patients ebv-transformed pbmcs genetic-linkage single-nucleotide-polymorphism candidate-gene
Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and titanium amplicon pyrosequencing and metagenomic approaches.

PMID 19860898 · PMC2773781 · BMC microbiology · 2009 · 7 claims · 5 setups

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VLU infections are polymicrobial with no single bacterium colonizing the wounds

individual pooled second btefap quantitative bulk
Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.

PMID 19859549 · PMC2762604 · PloS one · 2009 · 8 claims · 8 setups

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A comprehensive platelet proteome of 1507 unique proteins was identified from ten independent human platelet samples, the most comprehensive platelet proteome assembled to date

platelets platelet anti-coagulated lc-ms phospho-proteomic membrane
Mutation analysis in primary immunodeficiency diseases: case studies.

PMID 19841577 · PMC2774237 · Current opinion in allergy and clinical immunology · 2009 · 8 claims · 8 setups

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Genomic DNA Sanger sequencing is the standard first-line approach for identifying PIDD-causing mutations but has limitations that can yield false-negative or false-positive results

mother parents ebv-transformed nemo genomic flow northern
Proteomic and genetic approaches identify Syk as an AML target.

PMID 19800574 · PMC2803063 · Cancer cell · 2009 · 8 claims · 8 setups

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EGFR inhibitors (e.g., gefitinib) induce AML differentiation through a non-EGFR, off-target mechanism

hl-60 aml molm-14 luciferase-labeled phospho-tyrosine kinome-wide secondary
Spontaneous mutations in hlyD and tuf genes result in resistance of Dickeya solani IPO 2222 to phage ϕD5 but cause decreased bacterial fitness and virulence in planta.

PMID 37160956 · PMC10169776 · Scientific reports · 2023 · 7 claims · 8 setups

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Spontaneous ΦD5-resistant D. solani mutants DsR34 and DsR207 show significantly reduced virulence and colonization ability in planta compared to wild-type

potato solani planta maceration genome
Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures.

PMID 36527260 · PMC10952672 · Glia · 2023 · 6 claims · 3 setups

Has reproduction · 26

The bulk microglial and monocyte transcriptomic program is highly contingent on the disease environment, challenging the notion of a universal microglial disease signature

acutely microglia c57bl meta-analysis integration spectral
The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells.

PMID 15661077 · PMC548512 · Respiratory research · 2005 · 6 claims · 3 setups

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IL-13 and IL-13R130Q modulate the same set of genes in human airway smooth muscle cells (HASMC)

airway hasmc cdna taqman flow
Empowering integrative and collaborative exploration of single-cell and spatial multimodal data with SGS genome browser.

PMID 40233745 · PMC12143324 · Cell genomics · 2025 · 8 claims · 6 setups

Has reproduction

SGS is a user-friendly, collaborative, versatile browser for integrative visualization of single-cell and spatial multimodal (scMulti-omics) data

dorsal hematopoietic brain onek1k sn-m3c-seq scatac-seq spatial
Tipping the balance in autoimmune disease.

PMID 18001485 · PMC2246277 · Genome biology · 2007 · 8 claims · 8 setups

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Human autoimmune diseases are fundamentally diseases of immune dysfunction, evidenced by predisposing genes being immune-function genes, some shared and some unique across MS, T1D, SLE, CD and RA

patients congenic nzm2410 mrl-lpr snp induced genetic
Glycomic analysis: an array of technologies.

PMID 19728746 · PMC3443568 · ACS chemical biology · 2009 · 8 claims · 8 setups

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Glycosylation is the most prevalent protein post-translational modification, occurring on at least 50% of all proteins

sera t-cells serum glycoproteins lectin hydrazide bioorthogonal
The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway.

PMID 35371105 · PMC8964954 · Frontiers in immunology · 2022 · 8 claims · 8 setups

Has reproduction · 50

HCV E1E2 glycoproteins, and more so E2, down-modulate HIV-1 LTR activation in 293T, TZM-bl and Huh7 cells

293t tzm-bl tzm-bl-e1e2 hiv-1 pseudo-typed transcriptomic
Environmental Drivers of Genetic Divergence in Two Corals From the Florida Keys.

PMID 40589611 · PMC12206660 · Evolutionary applications · 2025 · 8 claims · 8 setups

Has reproduction · 64

Temperature was not the most important driver of coral genetic divergence in the Florida Keys; depth and water chemistry were more important

agaricia agaricites coral sites 2brad population hierarchical
Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications.

PMID 12592375 · PMC2377180 · British journal of cancer · 2003 · 7 claims · 5 setups

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Unmutated VH gene CLL cases have significantly shorter telomeres than mutated VH gene CLL cases

cll subset pcr southern real-time
A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.

PMID 16941570 · PMC1869047 · Proteomics · 2006 · 8 claims · 7 setups

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96 proteins undergo post-translational modification (phosphorylation) in response to CRP stimulation of human platelets, including 11 proteins not previously identified in platelets

washed 293t g6f-transfected hek phosphotyrosine 2-de western

Experiments

Functional diversity of HIV-1 envelope proteins expressed by contemporaneous plasma viruses.

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.

Reduced transcription of TCOF1 in adult cells of Treacher Collins syndrome patients.

PCP consensus sequences of flaviviruses: correlating variance with vector competence and disease phenotype.

Tissue compartment analysis for biomarker discovery by gene expression profiling.

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.

Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and titanium amplicon pyrosequencing and metagenomic approaches.

Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.

Mutation analysis in primary immunodeficiency diseases: case studies.

Proteomic and genetic approaches identify Syk as an AML target.

Spontaneous mutations in hlyD and tuf genes result in resistance of Dickeya solani IPO 2222 to phage ϕD5 but cause decreased bacterial fitness and virulence in planta.

Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures.

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells.

Empowering integrative and collaborative exploration of single-cell and spatial multimodal data with SGS genome browser.

Tipping the balance in autoimmune disease.

Glycomic analysis: an array of technologies.

The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway.

Environmental Drivers of Genetic Divergence in Two Corals From the Florida Keys.

Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications.

A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.