Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Toward the use of genomics to study microevolutionary change in bacteria.
PMID 19855823 · PMC2756242 · PLoS genetics · 2009 · 7 claims · 5 setups
The clonal population structure of bacteria, combined with occasional DNA import, provides a powerful context for identifying genetic bases of adaptive phenotypes via association studies.
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Development of a microtiter plate-based glycosaminoglycan array for the investigation of glycosaminoglycan-protein interactions.
PMID 19729381 · PMC3428902 · Glycobiology · 2009 · 8 claims · 5 setups
Plasma-polymerized allyl amine:octadiene surfaces support non-covalent immobilization of diverse GAGs (heparin, chondroitin-4-sulfate, dermatan sulfate, hyaluronan) in a functionally active, protein-binding state
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Antibody binding loop insertions as diversity elements.
PMID 17023486 · PMC1635297 · Nucleic acids research · 2006 · 7 claims · 8 setups
A lysozyme-binding VHH CDR3 loop can be grafted into two surface-exposed loops of superfolder GFP, conferring lysozyme-binding activity while the protein remains fluorescent.
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Next-generation high-density self-assembling functional protein arrays.
PMID 18469824 · PMC3070491 · Nature methods · 2008 · 8 claims · 7 setups
A next-generation NAPPA method produces high-density protein microarrays displaying over 1500 unique proteins with >90% expression success