Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Translating genome sequences into biological understanding.
PMID 12801409 · PMC193614 · Genome biology · 2003 · 8 claims · 7 setups
Gene-trap insertional mutagenesis in mouse ES cells (BayGenomics) generates a large resource of cell lines and knockout mice for studying gene expression patterns and function.
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Has reproduction · 53
spliceJAC: transition genes and state-specific gene regulation from single-cell transcriptome data.
PMID 36321549 · PMC9627675 · Molecular systems biology · 2022 · 8 claims · 8 setups
spliceJAC uses unspliced and spliced mRNA count matrices to construct cell state-specific gene-gene regulatory interaction (Jacobian) matrices from scRNA-seq data
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FracFixR: a compositional statistical framework for absolute proportion estimation between fractions in RNA sequencing data.
PMID 41264734 · PMC12866640 · Bioinformatics (Oxford, England) · 2026 · 7 claims · 5 setups
FracFixR reconstructs original fraction proportions by modeling the compositional relationship between whole and fractionated RNA samples using non-negative least squares (NNLS) regression on selected transcripts
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Hit selection with false discovery rate control in genome-scale RNAi screens.
PMID 18628291 · PMC2504311 · Nucleic acids research · 2008 · 8 claims · 3 setups
A Bayesian FDR-controlling methodology for hit selection in genome-scale RNAi HTS is proposed, using a direct posterior probability approach analogous to Newton et al.