Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 89
Graph Random Forest: A Graph Embedded Algorithm for Identifying Highly Connected Important Features.
PMID 37509188 · PMC10377046 · Biomolecules · 2023 · 8 claims · 3 setups
Graph Random Forest (GRF) embeds graph/network information directly into the decision-tree building process by splitting on features in the k-hop neighborhood of a data-driven head-splitting node.
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Gene loss rate: a probabilistic measure for the conservation of eukaryotic genes.
PMID 17158152 · PMC1802574 · Nucleic acids research · 2007 · 8 claims · 8 setups
GLR is a novel maximum-likelihood measure of gene loss rate that probabilistically weighs all possible ancestral phyletic patterns rather than relying on a single parsimonious reconstruction.
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Has reproduction · 65
High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro.
PMID 35776646 · PMC9243297 · STAR protocols · 2022 · 8 claims · 8 setups
HT-SELEX enables unbiased, in vitro determination of preferred DNA target motifs for DNA-binding proteins by iterative selection and PCR amplification of bound oligonucleotides
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On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve.
PMID 18076765 · PMC2211327 · BMC bioinformatics · 2007 · 8 claims · 4 setups
The TGDR-AUC algorithm regularizes the empirical AUC by replacing the non-differentiable 0-1 loss with a smooth sigmoid surrogate function and applies constrained threshold gradient descent regularization
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Grammar-based distance in progressive multiple sequence alignment.
PMID 18616828 · PMC2478692 · BMC bioinformatics · 2008 · 7 claims · 3 setups
A grammar-based (LZ complexity) distance metric can be used to determine the order in which sequences are progressively pairwise aligned
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CorGen--measuring and generating long-range correlations for DNA sequence analysis.
PMID 16845099 · PMC1538783 · Nucleic acids research · 2006 · 8 claims · 3 setups
CorGen is a web server that measures long-range correlations in DNA sequences and generates random sequences with the same (or user-specified) correlation and composition parameters
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Has reproduction · 67
Generative and integrative modeling for transcriptomics with formalin fixed paraffin embedded material.
PMID 41029822 · PMC12486589 · Journal of translational medicine · 2025 · 8 claims · 5 setups
fRNA-seq transcript counts are best fit by the negative binomial distribution, with little evidence supporting zero-inflated extensions
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Has reproduction · 77
Accurate chromatin marks peak calling with Omnipeak.
PMID 41521664 · PMC12784980 · Nucleic acids research · 2026 · 8 claims · 6 setups
Omnipeak is a universal unsupervised peak-calling algorithm based on a constrained three-state hidden Markov model (zero, noise, signal states)