Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Novel peptide identification from tandem mass spectra using ESTs and sequence database compression.
PMID 17437027 · PMC1865584 · Molecular systems biology · 2007 · 7 claims · 6 setups
Traditional protein-sequence-database search engines fail to identify peptides from alternative splicing and coding SNP isoforms despite acquisition of good-quality tandem mass spectra
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Tags for labeling protein N-termini with subtiligase for proteomics.
PMID 18762420 · PMC2590642 · Bioorganic & medicinal chemistry letters · 2008 · 6 claims · 4 setups
Arginine-rich peptide esters (3, 4, 5) are markedly more soluble than the original TEVest2 ester (1) and give significantly higher N-terminal tagging of proteins by subtiligase at higher concentrations.
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Has reproduction · 73
Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples.
PMID 29221171 · PMC5707065 · Oncotarget · 2017 · 8 claims · 6 setups
A customised SAAV peptide database built from RNA-seq/WGS variant calls can be used to search proteomics data and detect single amino acid variant (SAAV)-containing peptides at the protein level
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Phosphoproteomics: new insights into cellular signaling.
PMID 16168091 · PMC1242200 · Genome biology · 2005 · 8 claims · 8 setups
Protein kinases are one of the largest gene families in humans and mice, accounting for 1.7% of the human genome