Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Tags for labeling protein N-termini with subtiligase for proteomics.
PMID 18762420 · PMC2590642 · Bioorganic & medicinal chemistry letters · 2008 · 6 claims · 4 setups
Arginine-rich peptide esters (3, 4, 5) are markedly more soluble than the original TEVest2 ester (1) and give significantly higher N-terminal tagging of proteins by subtiligase at higher concentrations.
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Proteomic analyses of monocyte-derived macrophages infected with human immunodeficiency virus type 1 primary isolates from Hispanic women with and without cognitive impairment.
PMID 19115125 · PMC2947716 · Journal of neurovirology · 2009 · 7 claims · 5 setups
HIV-1 isolates from CI patients induce a distinct macrophage proteome signature compared to isolates from NC patients and SF162
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Pilot proteomic profile of differentially regulated proteins in right atrial appendage before and after cardiac surgery using cardioplegia and cardiopulmonary bypass.
PMID 18824761 · PMC2629397 · Circulation · 2008 · 8 claims · 3 setups
CP/CPB causes multiple consistent, reproducible changes in the human myocardial (right atrial) protein profile
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Human microglial cells synthesize albumin in brain.
PMID 18665237 · PMC2483733 · PloS one · 2008 · 8 claims · 8 setups
Human microglial cells synthesize albumin de novo in the brain.
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Mass spectrometry for proteomics.
PMID 18718552 · PMC2642903 · Current opinion in chemical biology · 2008 · 8 claims · 8 setups
New instrumentation (Orbitrap) and new fragmentation methods (ETD) have enabled exciting new areas of proteomic application