Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: cell-type ✕ Assay: targeted ✕ Clear

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.

PMID 41621066 · PMC13050545 · Cell reports · 2026 · 8 claims · 8 setups

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FOXA1 mutations in a 874-tumor cohort cluster into missense, in-frame indel, and truncation subgroups, with indels concentrated at residues M253/E255

prostate targeted single-nucleus scatac-seq
Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson's and inflammatory bowel disease.

PMID 41545356 · PMC12847817 · NPJ Parkinson's disease · 2026 · 8 claims · 5 setups

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Spatial single-cell multiomic imaging of sigmoid colon reveals both shared and unique features of peripheral immune dysfunction in PD and IBD

sigmoid plasma stool epithelial cosmx meso gene
Berberine suppresses colon inflammation via integrated modulation of host metabolism, microbial ecology, and innate immune signaling.

PMID 41356191 · PMC12680593 · Theranostics · 2026 · 6 claims · 8 setups

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Berberine enhances energy metabolism (oxidative phosphorylation, ATP biosynthesis, fatty acid metabolism) in intestinal epithelial cells of DSS-induced mice, preserving normal physiological function

colon feces serum dss-induced single-cell targeted 16s
Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.

PMID 41651833 · PMC12988232 · Nature communications · 2026 · 8 claims · 8 setups

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IPA is consistently depleted in IBD/colitis patients and in murine colitis models relative to healthy controls

fecal c57bl germ-free mice quasi-targeted dss-induced tnbs-induced
Dopamine enhances surface glial glycolysis via acetylcholine and insulin/insulin-like growth factor signaling in the honeybee.

PMID 41797926 · PMC12964235 · iScience · 2026 · 8 claims · 5 setups

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Bromocriptine (dopamine receptor agonist) increases glycolytic flux in forager bee brains

forager targeted qpcr single-cell
DNA methylation profiles at hospital admission are associated with subsequent severe COVID-19 outcomes.

PMID 42021404 · PMC13251264 · Clinical epigenetics · 2026 · 7 claims · 5 setups

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DNA methylation profiles at hospital admission differ among disease trajectory groups (TGs) and are associated with subsequent disease progression.

pbmcs blood immune end-stage targeted rna-seq mass
Enteroendocrine cell lineages that differentially control feeding and gut motility.

PMID 36810133 · PMC10032656 · eLife · 2023 · 6 claims · 8 setups

Has reproduction · 88

Vil1-p2a-FlpO knock-in mice combined with lineage-specific Cre lines enable highly selective intersectional genetic access to major enteroendocrine cell lineages (serotonin/enterochromaffin, GLP1, CCK, somatostatin, GIP) in vivo

neurod1-cre neurog3-cre intestinal vil1-p2a-flpo single-cell fluorescence-activated two-color
Multiomics assessment of lung adenocarcinoma subtypes defined through tumor purity-adjusted DNA methylation.

PMID 41691315 · PMC12927254 · Genome medicine · 2026 · 8 claims · 8 setups

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Tumor purity-adjusted DNA methylation profiling of 95 primary LUAD samples identifies four distinct epigenetic subtypes (epitypes M1-M4)

luad methylation sequencing targeted
Single-nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification.

PMID 41537454 · PMC12805614 · The Journal of pathology · 2026 · 6 claims · 7 setups

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snRNA-seq identifies a novel tenogenic heterologous differentiation program (SCX, MKX, TNMD) in an endometrial carcinosarcoma

ffpe sections tumor cs4 single-nucleus immunohistochemistry fluorescence

Experiments

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.

Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson's and inflammatory bowel disease.

Berberine suppresses colon inflammation via integrated modulation of host metabolism, microbial ecology, and innate immune signaling.

Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.

Dopamine enhances surface glial glycolysis via acetylcholine and insulin/insulin-like growth factor signaling in the honeybee.

DNA methylation profiles at hospital admission are associated with subsequent severe COVID-19 outcomes.

Enteroendocrine cell lineages that differentially control feeding and gut motility.

Multiomics assessment of lung adenocarcinoma subtypes defined through tumor purity-adjusted DNA methylation.

Single-nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification.