Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: patient-derived ✕ Assay: test ✕ Clear

Computational modeling demonstrates that glioblastoma cells can survive spatial environmental challenges through exploratory adaptation.

PMID 31836713 · PMC6911112 · Nature communications · 2019 · 8 claims · 6 setups

Has reproduction · 100

Exploratory adaptation (stochastic gene-regulatory network perturbation) explains how GBM cells adapt phenotypically across spatially distinct tumor regions

patient-derived low-grade tf-gene single-sample bulk differential gene
Technical challenges in using human induced pluripotent stem cells to model disease.

PMID 19951687 · PMC2921621 · Cell stem cell · 2009 · 8 claims · 8 setups

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hiPSCs generated from patient somatic cells (skin, blood) can be differentiated into disease-relevant cell types to model disease pathogenesis in vitro

ipscs humanized hemophilia parkinsonian tetraploid transplantation neuronal
High-resolution array comparative genomic hybridization of single micrometastatic tumor cells.

PMID 18344524 · PMC2367728 · Nucleic acids research · 2008 · 7 claims · 8 setups

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A protocol combining PCR-based whole genome amplification with arrays of highly purified BAC clones enables detection of DNA copy number changes in single cells

single bac amplified pi-scei array quantitative dot
SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data.

PMID 15961730 · PMC1151590 · Nucleic acids research · 2005 · 7 claims · 5 setups

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SW-ARRAY, an adaptation of the Smith-Waterman dynamic programming algorithm, provides a sensitive and robust method for identifying copy-number changes in array CGH data

chromosome 16p array probe-by-probe sw-array

Experiments

Computational modeling demonstrates that glioblastoma cells can survive spatial environmental challenges through exploratory adaptation.

Technical challenges in using human induced pluripotent stem cells to model disease.

High-resolution array comparative genomic hybridization of single micrometastatic tumor cells.

SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data.