Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SysPIMP: the web-based systematical platform for identifying human disease-related mutated sequences from mass spectrometry.
PMID 19036792 · PMC2686442 · Nucleic acids research · 2009 · 8 claims · 7 setups
SysPIMP is a web-based platform integrating disease mutation databases with X!Tandem and BLAST to identify disease-related mutated proteins from MS results
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G2Cdb: the Genes to Cognition database.
PMID 18984621 · PMC2686544 · Nucleic acids research · 2009 · 7 claims · 7 setups
G2Cdb integrates experimentally validated synapse proteome datasets with mouse/human genomic annotation, phenotype, and human disease data in a gene-centric database.
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SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions.
PMID 19934256 · PMC2808967 · Nucleic acids research · 2010 · 8 claims · 6 setups
SuperCYP is a comprehensive relational database aggregating CYP enzyme, drug metabolism, SNP/mutation, and structural information from literature and web resources.
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Proteomic-based identification of maternal proteins in mature mouse oocytes.
PMID 19646285 · PMC2730056 · BMC genomics · 2009 · 8 claims · 6 setups
625 different proteins were identified from 2700 zona pellucida-free mature mouse MII oocytes, the largest oocyte proteome catalog to date
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Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts.
PMID 19649302 · PMC2709445 · PLoS computational biology · 2009 · 7 claims · 4 setups
A computational framework can build disease-specific drug-protein connectivity maps by integrating protein interaction networks and PubMed literature mining, without gene expression profiles from drug perturbation experiments
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Discovery of protein-protein interactions using a combination of linguistic, statistical and graphical information.
PMID 15941473 · PMC1164402 · BMC bioinformatics · 2005 · 8 claims · 5 setups
A combined linguistic+statistical+rule-based method achieves precision 0.61 and recall 0.97 (f=0.74) detecting yeast protein-protein interactions across 12,300 Medline abstracts.
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Has reproduction · 94
Systematic assessment of pathway databases, based on a diverse collection of user-submitted experiments.
PMID 36088548 · PMC9487593 · Briefings in bioinformatics · 2022 · 8 claims · 6 setups
Well-established, hierarchically organized pathway annotation systems (e.g. GO, Reactome, KEGG) yield the best overall enrichment performance despite covering much of the human genome only in general terms.