Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: gfp+ ✕ Assay: tgf-β ✕ Clear

Spatially resolved osteoblast-traced transcriptomics uncovers TGF-β as a combination target with sclerostin in osteoporosis.

PMID 41927532 · PMC13046724 · Bone research · 2026 · 8 claims · 8 setups

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Spatially resolved osteoblast-traced transcriptomics (lineage tracing + SLACS) identifies TGF-β signaling as a regulator of osteoblast activation state on quiescent bone surfaces

dmp1-creert2 gfp+ spatial mc3t3-e1 spatially cell-type gsea
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.

PMID 19012953 · PMC2990916 · Cell · 2008 · 7 claims · 8 setups

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shRNA pools targeting genes recurrently deleted in human HCC accelerate hepatocarcinogenesis in vivo, whereas randomly selected shRNA pools do not.

hepatocellular p53 genomic hepatoma array-based pooled shrna
Notch3 regulates pericyte phenotypic plasticity in colorectal cancer.

PMID 41618002 · PMC12960917 · Communications biology · 2026 · 8 claims · 8 setups

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Murine tumor pericytes originate from normal tissue-resident pericytes that proliferate inside tumors

aom crc pdgfrβ-creert2 notch3-creert2 scrna-seq facs lineage
Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.

PMID 41673768 · PMC12998334 · Journal of experimental & clinical cancer research : CR · 2026 · 6 claims · 8 setups

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Organoids derived from malignant effusions of PDAC patients reproducibly generate peritoneal metastases after orthotopic implantation into the pancreas of immunodeficient mice

pdac organoids frozen pdox orthotopic single-nucleus single-cell

Experiments

Spatially resolved osteoblast-traced transcriptomics uncovers TGF-β as a combination target with sclerostin in osteoporosis.

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.

Notch3 regulates pericyte phenotypic plasticity in colorectal cancer.

Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.