Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Survival analysis with high-dimensional covariates.
PMID 19654171 · PMC4806549 · Statistical methods in medical research · 2010 · 8 claims · 1 setups
The classical Cox proportional hazards model cannot be fit when p >> n because the partial likelihood maximizer is not unique and the matrix X^T A X is singular in the IRLS procedure
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Has reproduction · 63
Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.
PMID 36323713 · PMC9630272 · Nature communications · 2022 · 8 claims · 8 setups
Loss of AR in stromal Gli1-lineage cells diminishes prostate epithelial oncogenesis and tumor development in vivo
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cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer.
PMID 19671129 · PMC2731783 · BMC cancer · 2009 · 8 claims · 6 setups
cDNA sequencing detects P53 missense mutations in colorectal cancer more frequently and reliably than DNA sequencing
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Has reproduction
miRge3.0: a comprehensive microRNA and tRF sequencing analysis pipeline.
PMID 34308351 · PMC8294687 · NAR genomics and bioinformatics · 2021 · 8 claims · 6 setups
miRge3.0 is a Python 3-based small RNA-seq and tRF analysis pipeline that improves on miRge2.0 (which was Python 2.7-based)
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Has reproduction · 76
A cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a.
PMID 28642491 · PMC5481429 · Scientific reports · 2017 · 8 claims · 8 setups
Hnf4a is a major transcriptional regulator of Dnajc22
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Frag'n'Flow: automated workflow for large-scale quantitative proteomics in high performance computing environments.
PMID 41486154 · PMC12828970 · BMC bioinformatics · 2026 · 8 claims · 8 setups
Frag'n'Flow is a Nextflow-based pipeline that encapsulates FragPipe, automating manifest/workflow generation, tool dependency management, and downstream analysis for HPC/cloud/cluster environments.
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In silico promoters: modelling of cis-regulatory context facilitates target predictio.
PMID 18505473 · PMC3823354 · Journal of cellular and molecular medicine · 2009 · 8 claims · 8 setups
An integrated 'profiling of transcriptional targets' (PTT) strategy by Freebern et al. identified IGF-1 as a co-modulator of immune cell function genes in mitogen/drug-activated T cells.