Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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FatiGO +: a functional profiling tool for genomic data. Integration of functional annotation, regulatory motifs and interaction data with microarray experiments.
PMID 17478504 · PMC1933151 · Nucleic acids research · 2007 · 8 claims · 8 setups
FatiGO+ is a web-based tool for functional profiling of genome-scale experiments that integrates functional annotation, regulatory motifs and interaction data
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Has reproduction · 53
Combining evidence of preferential gene-tissue relationships from multiple sources.
PMID 23950964 · PMC3741196 · PloS one · 2013 · 8 claims · 8 setups
A high-level integration approach combining three methods across four human microarray datasets, merged by consensus voting and a rule-based inner/total score, predicts preferentially expressed genes while reducing method- and study-specific bias.
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Organismal complexity, cell differentiation and gene expression: human over mouse.
PMID 17881362 · PMC2095826 · Nucleic acids research · 2007 · 8 claims · 7 setups
Human shows a greater fraction of tissue-specific genes and a greater ratio of total expression of tissue-specific to housekeeping genes than mouse across 32 homologous tissues
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All systems GO for understanding mouse gene function.
PMID 15610553 · PMC549721 · Journal of biology · 2004 · 7 claims · 4 setups
Quantitative, multivariate cross-tissue expression measurements are powerfully predictive of gene function
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Large-scale discovery and validation of functional elements in the human genome.
PMID 15774039 · PMC1088940 · Genome biology · 2005 · 8 claims · 8 setups
Genome-wide tiling microarray hybridization reveals large, diverse sets of transcripts, many of which lack existing gene annotations
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GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist.
PMID 18795106 · PMC2532782 · Experimental diabetes research · 2008 · 6 claims · 4 setups
GeneSpeed Beta Cell is an online genomics data repository allowing simultaneous multiexperiment viewing and multidimensional (Boolean intersection/union) querying of pancreas- and islet-relevant datasets, integrated with GeneSpeed's domain-based gene categorization.
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Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology.
PMID 18618001 · PMC2442223 · PLoS genetics · 2008 · 8 claims · 6 setups
Zebrafish whole-adult-organism chemogenomics generates robust prediction models that discriminate P(H)AHs from ECs across independent experiments
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GOLD.db: genomics of lipid-associated disorders database.
PMID 15588328 · PMC544894 · BMC genomics · 2004 · 8 claims · 4 setups
GOLD.db integrates annotated pathways, gene/protein reference information, and curated gene expression datasets for lipid-associated disorders research
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TFBScluster web server for the identification of mammalian composite regulatory elements.
PMID 16845063 · PMC1538905 · Nucleic acids research · 2006 · 7 claims · 5 setups
TFBScluster is a web server that identifies genome-wide clusters of TFBSs conserved in multiple mammalian species using human or mouse as the reference genome.
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Epigenetics and phenotypic variation in mammals.
PMID 16688527 · PMC3906716 · Mammalian genome : official journal of the International Mammalian Genome Society · 2006 · 8 claims · 8 setups
Epigenetic modifications are mitotically heritable, but the fidelity of meiotic/transgenerational inheritance in mammals is poorly understood and evidence in mammals is scanty.
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GeneTide--Terra Incognita Discovery Endeavor: a new transcriptome focused member of the GeneCards/GeneNote suite of databases.
PMID 15608261 · PMC540076 · Nucleic acids research · 2005 · 8 claims · 7 setups
GeneTide integrates UniGene, DoTS, AceView, BLAT/GeneLoc genomic alignment, and GeneAnnot probe-set data into a unified Consensus/Uniqueness/Score scheme to associate ESTs with GeneCards genes
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Inference of transcriptional regulation using gene expression data from the bovine and human genomes.
PMID 17683551 · PMC1978505 · BMC genomics · 2007 · 7 claims · 8 setups
Using human reference promoter sequences is a useful approach for studying gene expression regulation in species with limited or non-existing genomic sequence, such as cattle.
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The biological function of some human transcription factor binding motifs varies with position relative to the transcription start site.
PMID 18367472 · PMC2377430 · Nucleic acids research · 2008 · 8 claims · 5 setups
1226 eight-letter DNA words show statistically significant positional preferences relative to the TSS across 7914 human promoter regions
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miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes.
PMID 16381831 · PMC1347497 · Nucleic acids research · 2006 · 6 claims · 6 setups
miRNAMap integrates known miRNA genes from miRBase, literature-curated validated targets, and computationally predicted miRNA genes and targets for human, mouse, rat and dog.
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SilkDB v2.0: a platform for silkworm (Bombyx mori ) genome biology.
PMID 19793867 · PMC2808975 · Nucleic acids research · 2010 · 8 claims · 8 setups
A new 8.5x-coverage silkworm genome assembly with N50 scaffold size of ~3.7 Mb over a 432 Mb genome represents a significant quality improvement over the prior draft.