Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 88
An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC.
PMID 40463960 · PMC12131257 · iScience · 2025 · 8 claims · 7 setups
SFPQ-TFE3 expression is sufficient to transform normal kidney epithelial tubuloids into tRCC
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BCG-trained macrophages promote pan-anti-tumor activity through epigenetic rewiring of NOX2-ROS axis.
PMID 42032669 · PMC13261971 · Journal of experimental & clinical cancer research : CR · 2026 · 7 claims · 8 setups
BCG training induces pan-anti-tumor activity across multiple mouse tumor models, mediated predominantly by tumor-associated macrophages (TAMs)
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Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities.
PMID 41037662 · PMC12877751 · Cancer discovery · 2026 · 8 claims · 7 setups
ATAC-seq profiling of osteosarcoma patient samples, PDXs, and PDX-CLs reveals two distinct chromatin accessibility subtypes: early osteoblast-derived (EOD) and late osteoblast-derived (LOD)
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APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer.
PMID 41790555 · PMC13123626 · Cell reports · 2026 · 8 claims · 8 setups
SETD8 Thr138 (mouse)/Thr140 (human) is a bona fide GSK3 phosphorylation site whose phosphorylation is dependent on APC in vivo and in vitro