Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Disruption of tRNA threonylation triggers RIG-I mediated anti-tumour immune response.

  PMID 41735308 · PMC13043769 · Nature communications · 2026 · 8 claims · 8 setups

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  OSGEP is the catalytic subunit of the KEOPS complex responsible for t6A modification at position 37 of cytoplasmic tRNAs, and its loss causes the highest protein aggregation among 45 screened tRNA-modifying enzymes in melanoma cells

  mm117 b16f10 b16f10-derived c57bl esirna shrna rna-seq

• Synthetic super-enhancers enable precision viral immunotherapy.

  PMID 41951744 · PMC13149004 · Nature · 2026 · 8 claims · 8 setups

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  Synthetic super-enhancers (SSEs) assembled from validated 160 bp SOX2/SOX9-bound enhancer fragments achieve strong and highly selective transcriptional activity in glioblastoma stem cells (GSCs)

  gsc7 patient-derived seven id2904 luciferase flow chip-seq

• Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers.

  PMID 41986711 · PMC13233332 · Nature · 2026 · 8 claims · 7 setups

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  Metastasis-associated oncofetal cell states emerge already at the earliest stages of colorectal cancer, concurrent with invasive front formation

  stage crc multiregional patient-derived spatial immunofluorescence whole-genome