Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Toxicoproteomics: a parallel approach to identifying biomarkers.
PMID 12940285 · PMC1241639 · Environmental health perspectives · 2003 · 8 claims · 8 setups
Combining parallel DNA microarray and proteomic analyses on the same tissues merges microarray's gene discovery power with proteomics' ability to exploit post-translational modifications for biomarker identification.
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A statistical model to identify differentially expressed proteins in 2D PAGE gels.
PMID 19763172 · PMC2734266 · PLoS computational biology · 2009 · 7 claims · 5 setups
A mixture likelihood model incorporating both detected and non-detected proteins has higher statistical power to detect differential expression than standard approaches like the Student's t-test.
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The role of genomics in tracking the evolution of influenza A virus.
PMID 19855818 · PMC2739293 · PLoS pathogens · 2009 · 8 claims · 5 setups
Antigenic drift, driven by selection for amino acid changes in exposed hemagglutinin epitope sites, is the main mechanism by which influenza A evades pre-existing immunity between pandemics.
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Has reproduction · 100
A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer.
PMID 35047825 · PMC8759566 · NAR cancer · 2022 · 7 claims · 7 setups
Five miRNAs (Mir-210_3p, Mir-191_5p, Mir-8-P1b_3p [miR-141-3p], Mir-1307_5p, Mir-155_5p) are up-regulated at multiple metastatic sites in colorectal cancer.