Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Integrative bulk and single-cell transcriptomics link EZH2 to immunosuppressive programs and tumor-Treg crosstalk in castration-resistant prostate cancer.

  PMID 41710887 · PMC12909565 · Frontiers in immunology · 2026 · 8 claims · 8 setups

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  Higher EZH2 expression is associated with adverse clinical outcomes in bulk PCa/CRPC cohorts

  tcga-prad su2c gse264573 gse137829 bulk scrna-seq ligand-receptor

• Fibroblast-associated CTHRC1 as a key indicator of recurrence risk in prostate cancer.

  PMID 41832493 · PMC13101373 · World journal of surgical oncology · 2026 · 7 claims · 8 setups

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  Pathological T stage, N stage, Gleason score, and TP53 mutation are associated with higher PRAD recurrence risk

  tcga geo prad scrna-seq bulk single-cell cell-cell

• Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection.

  PMID 31533612 · PMC6751684 · BMC bioinformatics · 2019 · 8 claims · 6 setups

  Has reproduction · 69

  An ensemble feature selection strategy using consensus of feature relevance across 8 classifier types identifies a 100-miRNA signature from a 1046-feature TCGA dataset

  tcga geo mirnas mirna feature bibliographic

• Multi-omics analyses related to unfolded protein response in prostate cancer implicate pro-tumor role of IFRD1.

  PMID 41694360 · PMC12894258 · Frontiers in immunology · 2026 · 8 claims · 8 setups

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  Luminal prostate epithelial cells, especially the LE-KLK3 subpopulation, show elevated UPR activity compared to other cell types

  pca tcga-prad external scrna-seq bulk immune

• Single-Cell and Spatial Transcriptomics Reveal That TXNIP and BIRC3 Contribute to Human Prostate Tumor Progression.

  PMID 41972735 · PMC13072731 · Cells · 2026 · 6 claims · 8 setups

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  TXNIP and BIRC3 are established as spatially restricted tumor-niche genes associated with metabolic stress and inflammatory survival pathways

  prostate tcga-prad integration single-cell spatial pseudotime