Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 87
Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity.
PMID 35418127 · PMC9008010 · Scientific data · 2022 · 6 claims · 5 setups
This dataset is the most comprehensive public-facing dataset of ultra-deep ctDNA sequencing data generated to date
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Has reproduction · 96
Calibration-free NGS quantitation of mutations below 0.01% VAF.
PMID 34675197 · PMC8531361 · Nature communications · 2021 · 8 claims · 6 setups
QBDA (Quantitative Blocker Displacement Amplification) integrates UMI molecular barcoding with BDA variant enrichment to enable calibration-free VAF quantitation
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Has reproduction
miRge3.0: a comprehensive microRNA and tRF sequencing analysis pipeline.
PMID 34308351 · PMC8294687 · NAR genomics and bioinformatics · 2021 · 8 claims · 6 setups
miRge3.0 is a Python 3-based small RNA-seq and tRF analysis pipeline that improves on miRge2.0 (which was Python 2.7-based)
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Has reproduction · 92
Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes.
PMID 28446242 · PMC5406893 · Genome medicine · 2017 · 8 claims · 7 setups
Application of GFRN pathway signatures to breast tumor gene expression data identifies two discrete phenotypes: a 'survival phenotype' (concordant activation of HER2, IGF1R, AKT) and a 'growth phenotype' (concordant activation of EGFR, KRAS(G12V), RAF1, BAD)