Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 85
Prediction of condition-specific regulatory genes using machine learning.
PMID 32329779 · PMC7293043 · Nucleic acids research · 2020 · 8 claims · 6 setups
ConSReg integrates expression, DAP-seq TF-DNA binding, and ATAC-seq open chromatin data into machine learning models to predict condition-specific regulatory genes
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Integrating alternative splicing detection into gene prediction.
PMID 15705189 · PMC550657 · BMC bioinformatics · 2005 · 8 claims · 4 setups
An integrative intrinsic/extrinsic method was implemented in the gene finder EuGÈNE (as EuGÈNE-M) to detect AS evidence from aligned transcripts and generate alternative optimal gene predictions consistent with each detected AS event.
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Has reproduction · 84
Foster thy young: enhanced prediction of orphan genes in assembled genomes.
PMID 34928390 · PMC9023268 · Nucleic acids research · 2022 · 7 claims · 8 setups
Each of the five gene-prediction pipelines under-predicts orphan genes, with detection as low as 11% under one prediction scenario.
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Comparative analysis of plant genomes allows the definition of the "Phytolongins": a novel non-SNARE longin domain protein family.
PMID 19889231 · PMC2779197 · BMC genomics · 2009 · 8 claims · 6 setups
A novel, plant-specific family of longin-related proteins, the 'Phytolongins', was identified in land plant genomes.
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Classification of real and pseudo microRNA precursors using local structure-sequence features and support vector machine.
PMID 16381612 · PMC1360673 · BMC bioinformatics · 2005 · 7 claims · 7 setups
A 32-dimensional triplet structure-sequence feature vector combined with SVM (triplet-SVM) can distinguish real human pre-miRNAs from pseudo pre-miRNA hairpins with ~90% accuracy.
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Accurate splice site prediction using support vector machines.
PMID 18269701 · PMC2230508 · BMC bioinformatics · 2007 · 8 claims · 5 setups
Weighted degree (WD) kernel SVMs outperform Markov Chains, GeneSplicer and SpliceMachine for genome-wide splice site recognition
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Has reproduction · 58
Genome-wide identification and characterization of germin-like protein family in Brassica juncea reveals their role against biotic stress.
PMID 41327045 · PMC12763953 · BMC plant biology · 2025 · 8 claims · 8 setups
102 GLPs were identified in B. juncea, 51 in B. nigra, and 48 in B. rapa via genome-wide in-silico analysis
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Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals.
PMID 13678422 · PMC222960 · BMC bioinformatics · 2003 · 8 claims · 8 setups
The human genome encodes at least 71 kelch-repeat proteins
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Inparanoid: a comprehensive database of eukaryotic orthologs.
PMID 15608241 · PMC540061 · Nucleic acids research · 2005 · 8 claims · 4 setups
The Inparanoid algorithm identifies true ortholog clusters by seeding on reciprocal best-matching pairs, gathering inparalogs (post-speciation duplicates) while excluding outparalogs (pre-speciation duplicates)