Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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A searchable database of genetic evidence for psychiatric disorders.
PMID 18548508 · PMC2574546 · American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2008 · 8 claims · 4 setups
SLEP (Sullivan Lab Evidence Project) is a freely available, searchable web database of findings from psychiatric genetics for non-commercial use.
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COMUS: Clinician-Oriented locus-specific MUtation detection and deposition System.
PMID 19958500 · PMC2788389 · BMC genomics · 2009 · 8 claims · 6 setups
COMUS is a bioinformatics system for detecting and depositing new mutations from patient DNA with a clinician-friendly interface
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Has reproduction · 80
MCPmed: a call for Model Context Protocol-enabled bioinformatics web services for LLM-driven discovery.
PMID 41729821 · PMC12927880 · Briefings in bioinformatics · 2026 · 6 claims · 3 setups
Adapting MCP to bioinformatics web server backends provides a standardized, machine-actionable semantic layer linking API endpoints to scientific concepts and metadata.
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Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes.
PMID 16757574 · PMC1475747 · Nucleic acids research · 2006 · 6 claims · 8 setups
Applying seven independent computational disease-gene prioritization methods in concert to 9556 positional candidate genes identifies a prioritized set of likely T2D and obesity candidate genes
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Web services and workflow management for biological resources.
PMID 16351751 · PMC1866383 · BMC bioinformatics · 2005 · 8 claims · 4 setups
Workflow management systems combined with Web Services are a promising ICT approach for automating access to and integration of biomedical data.
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Columba: an integrated database of proteins, structures, and annotations.
PMID 15801979 · PMC1087474 · BMC bioinformatics · 2005 · 8 claims · 6 setups
COLUMBA physically integrates data from twelve protein structure-related databases (PDB, KEGG, Swiss-Prot, CATH, SCOP, Gene Ontology, ENZYME, etc.) into a single PostgreSQL data warehouse.
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An integrated database-pipeline system for studying single nucleotide polymorphisms and diseases.
PMID 19091018 · PMC2638159 · BMC bioinformatics · 2008 · 6 claims · 5 setups
Existing SNP/disease databases are fragmented; no combined resource widely supports gene-, SNP-, and disease-related information together
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Has reproduction
All of gene expression (AOE): An integrated index for public gene expression databases.
PMID 31978081 · PMC6980531 · PloS one · 2020 · 8 claims · 5 setups
AOE integrates publicly available gene expression data from GEO, ArrayExpress, and GEA into a single searchable index.
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A comprehensive literature review of haplotyping software and methods for use with unrelated individuals.
PMID 15814067 · PMC3525117 · Human genomics · 2005 · 7 claims · 2 setups
Forty-six haplotyping programs were identified and reviewed, split into 43 designed for individual genotype data and three designed for pooled DNA samples.
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LMPD: LIPID MAPS proteome database.
PMID 16381922 · PMC1347484 · Nucleic acids research · 2006 · 8 claims · 5 setups
LMPD is an object-relational database of lipid-associated protein sequences and annotations, publicly available from the LIPID MAPS Consortium website.
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Has reproduction · 74
Wide-Open: Accelerating public data release by automating detection of overdue datasets.
PMID 28594819 · PMC5464523 · PLoS biology · 2017 · 7 claims · 5 setups
Wide-Open is a general text-mining approach that automatically detects overdue datasets by scanning PubMed articles for dataset accession identifiers and querying repositories to determine if the datasets remain private.
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TPRpred: a tool for prediction of TPR-, PPR- and SEL1-like repeats from protein sequences.
PMID 17199898 · PMC1774580 · BMC bioinformatics · 2007 · 7 claims · 8 setups
TPRpred detects divergent/remote-homolog TPR repeat units that existing resources (Pfam, SMART, REP) fail to detect
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Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information.
PMID 19651875 · PMC2761287 · Nucleic acids research · 2009 · 8 claims · 7 setups
The LCV approach predicts HTH motifs with 93.29% accuracy, 93.93% sensitivity and 92.66% specificity using only primary sequence information
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An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results.
PMID 15005801 · PMC341449 · BMC bioinformatics · 2004 · 7 claims · 3 setups
An XML schema called Annotated Gel Markup Language (AGML) is proposed to manage, analyze, and disseminate annotated 2D gel electrophoresis and MS results.