Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Modification at HuR(S242) alters HuR localization and proliferative influence.
PMID 18948743 · PMC2704553 · Cell cycle (Georgetown, Tex.) · 2008 · 8 claims · 8 setups
Systematic S→A mutagenesis of the seven hinge-region serines identifies S242 as a novel determinant of HuR subcellular localization
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Has reproduction · 99
Free circular introns with an unusual branchpoint in neuronal projections.
PMID 31697236 · PMC6879206 · eLife · 2019 · 8 claims · 7 setups
A set of free circular introns with a non-canonical (C) branchpoint is enriched in distal neuronal projections; these appear to be tailless lariats that escape debranching.
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Has reproduction · 76
PI3K inhibitors protect against glucocorticoid-induced skin atrophy.
PMID 30737086 · PMC6441871 · EBioMedicine · 2019 · 8 claims · 8 setups
Drug repurposing screen of the LINCS transcriptional signature database identified PI3K/mTOR/Akt inhibitors as the most prominent pharmacological class capable of repressing REDD1/FKBP51 expression.
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Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins.
PMID 17446074 · PMC1885954 · Current biology : CB · 2007 · 8 claims · 8 setups
Newly synthesized ribosomal proteins accumulate in nucleoli more quickly than other nucleolar proteins
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A chromosomally integrated bacteriophage in invasive meningococci.
PMID 15967821 · PMC2212043 · The Journal of experimental medicine · 2005 · 8 claims · 7 setups
An 8-kb genetic island (NMA1792-NMA1799) is specifically associated with hyperinvasive meningococcal clonal complexes