Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
Protein under-wrapping causes dosage sensitivity and decreases gene duplicability.
PMID 18208334 · PMC2211539 · PLoS genetics · 2008 · 7 claims · 6 setups
Protein under-wrapping extent is negatively correlated with gene duplicability (family size) across six organisms (E. coli, yeast, worm, fly, human, thale cress)
-
Full-text index only
Structure of protein interaction networks and their implications on drug design.
PMID 19876376 · PMC2760708 · PLoS computational biology · 2009 · 8 claims · 6 setups
Budding yeast and human PINs are scale-rich and configured as highly optimized tolerance (HOT) networks similar to Internet router-level topology, rather than scale-free networks formed by preferential attachment.
-
Full-text index only
Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development.
PMID 16800721 · PMC1483910 · PLoS medicine · 2006 · 8 claims · 8 setups
Multi-scale genomic similarities exist between four human lung cancer subtypes and the developing mouse lung, and these similarities are prognostically meaningful.
-
Full-text index only
A taxonomy of epithelial human cancer and their metastases.
PMID 20017941 · PMC2806369 · BMC medical genomics · 2009 · 8 claims · 6 setups
Unsupervised hierarchical clustering of 1566 primary epithelial tumors yields large tissue-enriched clusters (breast, colon/GI, lung, ovary, kidney) plus smaller prostate, thyroid-kidney, and mixed clusters