Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 41
Unveiling the immunometabolic landscape of colorectal cancer through PANoptosis-related gene expression.
PMID 41601652 · PMC12832467 · Frontiers in immunology · 2025 · 8 claims · 8 setups
PANoptosis-related genes show significant expression heterogeneity across CRC samples, with apoptosis-related genes comprising the largest proportion (87.4%)
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Tight junction-high and CDH17-positive cell population is the source of colorectal cancer liver metastases.
PMID 41484106 · PMC12881549 · Nature communications · 2026 · 8 claims · 8 setups
Loss/inhibition of IKKα unexpectedly promotes, rather than suppresses, CRC liver metastasis in patient-derived organoid (PDO) xenograft models.
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Dissecting tumor heterogeneity in colorectal cancer: uncovering the role of BCL2L1(+) cells through single-cell analysis.
PMID 41958675 · PMC13056825 · Frontiers in immunology · 2026 · 8 claims · 8 setups
scRNA-seq identifies five CRC tumor cell subtypes, with the C4 BCL2L1+ subtype predominantly enriched in liver metastases and showing enhanced proliferation, metabolic reprogramming, and anti-apoptotic activity
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Ultra-precision deconvolution of spatial transcriptomics decodes immune heterogeneity and fate-defining programs in tissues.
PMID 41862467 · PMC13168514 · Nature communications · 2026 · 8 claims · 8 setups
UCASpatial is a novel deconvolution algorithm that uses Shannon entropy-based gene weighting combined with weighted non-negative least squares to estimate cell-type composition from spatial transcriptomics data