Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Anterior diffuse retinoblastoma: mutational analysis and immunofluorescence staining.

  PMID 19653712 · PMC2810483 · Archives of pathology & laboratory medicine · 2009 · 6 claims · 7 setups

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  Anterior diffuse retinoblastoma, traditionally considered sporadic/nonheritable, can arise from a germline RB1 mutation and thus may be heritable

  enucleated tumor anterior immunofluorescence rb1 fine-needle

• Characterization of Human Genes Modulated by Porphyromonas gingivalis Highlights the Ribosome, Hypothalamus, and Cholinergic Neurons.

  PMID 34194426 · PMC8236716 · Frontiers in immunology · 2021 · 8 claims · 8 setups

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  Genes in the SRP-dependent cotranslational protein targeting to membrane (ER translocation) pathway and ribosomal subunit genes are strongly and specifically enriched for arginine and lysine residues, suggesting high susceptibility to gingipain cleavage.

  protein-coding coli recombinant postmortem proteome-wide gene gingipain

• Evaluating Prey Availability for the Rice's Whale (Balaenoptera ricei) Based on Environmental DNA.

  PMID 41537137 · PMC12796833 · Ecology and evolution · 2026 · 7 claims · 5 setups

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  eDNA metabarcoding detected significantly greater fish biodiversity (99 species, 62 families) than concurrent trawl surveys in Rice's whale core habitat

  seawater northeastern regional trimmed edna fish sanger

• Structured Promoter Variability in Epigenetically Regulated Operons Contributes to Surface Adaptation in Salmonella.

  PMID 41684216 · PMC12902445 · Microbial biotechnology · 2026 · 7 claims · 5 setups

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  Structured, recurrent promoter variation in epigenetically regulated operons is a novel layer of functional adaptation in Salmonella, complementing genetic and epigenetic mechanisms.

  complete annotated 220-nucleotide opvab comparative correlation blastn

• Resource Availability Modulates Gene Expression Across Life Stages in a Migratory Butterfly.

  PMID 41797265 · PMC12968515 · Molecular ecology · 2026 · 7 claims · 6 setups

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  Adult female exposure to host plants for egg-laying is associated with differential expression of ecdysteroid and juvenile-hormone pathway genes, consistent with endocrine regulation of reproductive readiness and the oogenesis–flight syndrome

  vanessa bulk gene kegg

• Integrative phenotypic and functional genomic characterization of virulence and antimicrobial resistance in Salmonella enterica isolates from reptiles.

  PMID 42245496 · PMC13230192 · Frontiers in microbiology · 2026 · 8 claims · 6 setups

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  Salmonella culture case positivity rate in reptiles submitted to BADDL (2018-2025) was 16.41%

  reptile salmonella selected wgs bacterial antibiotic whole-genome

• Immunosuppressive contribution of tumour-infiltrating B cells in human intrahepatic cholangiocarcinoma and their role in chemoimmunotherapy outcome.

  PMID 40889886 · PMC13217081 · Gut · 2026 · 8 claims · 7 setups

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  High density of CD20+ B cells in the peritumoural area is associated with improved disease-free survival in iCCA

  resected cd45+ scrna-seq peripheral immunohistochemistry kaplan-meier scrna-seq

• Ontogeny and transcriptional regulation of Thetis cells.

  PMID 41634202 · PMC13171621 · Nature · 2026 · 8 claims · 8 setups

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  TCs are radiosensitive haematopoietic cells derived from an IL7R+ progenitor, enriched in fetal liver

  cd45.1 il7r il7r-cre cx3cr1-cre bone fetal scrna-seq

• Functional human salivary gland organoids for tissue regeneration in chemically defined culture systems.

  PMID 41707649 · PMC12923968 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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  A chemically defined, Matrigel-free complete medium (CM) generates hSGOs with more cohesive spheroid morphology, organized epithelial layers, and improved apical polarization compared to keratinocyte medium (KM-S) or Matrigel-embedded conditions

  submandibular smg-derived hsgos smg bright-field h&e single-factor

• Convergent evolutionary shifts in AGT targeting between mitochondria and peroxisomes across mammal transitions to herbivory.

  PMID 41781394 · PMC12960970 · Nature communications · 2026 · 7 claims · 7 setups

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  Multiple herbivorous mammal lineages independently evolved disrupted or truncated MTS regions in AGXT, while the PTS1 motif remains functional across all examined species

  mammal agxt herbivorous tblastn cell-based immunofluorescence

• CDK4/6 inhibition mitigates chemotherapy-induced expansion of TP53-mutant clonal hematopoiesis.

  PMID 41814002 · PMC12987733 · Nature genetics · 2026 · 7 claims · 6 setups

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  Trilaciclib reduces chemotherapy-induced expansion of DDR-gene (TP53, PPM1D, CHEK2) clonal hematopoiesis across four randomized clinical trials and diverse chemotherapy regimens

  peripheral c57bl bone deep competitive flow

• The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus data repository.

  PMID 40926267 · PMC12421755 · Genome biology · 2025 · 8 claims · 3 setups

  Has reproduction · 99

  Across 253 manually curated studies (164,000+ samples), over 25% of critical metadata are omitted, with only 74.8% of relevant phenotypes available overall.

  randomly repositories geo manual automated

• Detection of ras gene mutations in human lung cancer: comparison of two screening assays based on the polymerase chain reaction.

  PMID 1486847 · PMC1519635 · Environmental health perspectives · 1992 · 8 claims · 3 setups

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  Somatic K-ras mutations were found in one-third of lung carcinomas studied, but no N-ras mutations were detected.

  lung plasmid pcr-based denaturing

• Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas.

  PMID 8144396 · PMC5919417 · Japanese journal of cancer research : Gann · 1994 · 5 claims · 3 setups

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  Flat colorectal adenomas have a significantly lower K-ras codon 12 mutation frequency than polypoid adenomas and cancers.

  flat polypoid colorectal k-ras

• Molecular genetic diagnosis of von Hippel-Lindau disease: analysis of five Japanese families.

  PMID 8641976 · PMC5921130 · Japanese journal of cancer research : Gann · 1996 · 5 claims · 3 setups

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  Four of five Japanese VHL disease families showed germ line VHL gene mutations, comprising 2 missense mutations, 1 deletion, and 1 splice-site mutation

  blood-derived hemangioblastoma single-strand direct sscp

• Analyses of the APC and TGF-beta type II receptor genes, and microsatellite instability in mucosal colorectal carcinomas.

  PMID 9330602 · PMC5921495 · Japanese journal of cancer research : Gann · 1997 · 5 claims · 3 setups

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  APC gene mutations occur in a substantial proportion (34.0%) of mucosal colorectal carcinomas, indicating APC involvement from the beginning of tumorigenesis in many early colorectal carcinomas

  mucosal apc tgf-β microsatellite

• Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary type.

  PMID 10622534 · PMC5926019 · Japanese journal of cancer research : Gann · 1999 · 8 claims · 3 setups

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  Novel somatic point mutations and an in-frame deletion were identified in RET exons 12 and 15 in sporadic MTC

  formalin-fixed corresponding sporadic pcr clinical

• Mutation and deletion analysis of GFR alpha-1, encoding the co-receptor for the GDNF/RET complex, in human brain tumours.

  PMID 10408842 · PMC2362327 · British journal of cancer · 1999 · 8 claims · 3 setups

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  No mutations were found in the coding region of GDNF in any of the 36 brain tumours analysed

  sporadic tumour tumour-derived pcr loss semi-quantitative

• Elderly Japanese women with cervical carcinoma show higher proportions of both intermediate-risk human papillomavirus types and p53 mutations.

  PMID 10098748 · PMC2362249 · British journal of cancer · 1999 · 8 claims · 3 setups

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  HPV DNA was detected in 44 of 46 (96%) cervical carcinomas from elderly women

  cervical paraffin-embedded pcr-based pcr-single-strand immunohistochemistry

• Genetic alterations in the coding region of the bak gene in uterine cervical carcinoma.

  PMID 12771926 · PMC2377111 · British journal of cancer · 2003 · 8 claims · 3 setups

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  A significant frequency of mutations (six missense, one silent) was found in the coding region of the bak gene (exons 3, 4, 6) in uterine cervical carcinoma

  uterine non-neoplastic stage pcr-sscp clinical