Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Use of modified U1 snRNAs to inhibit HIV-1 replication.

  PMID 17158512 · PMC1802557 · Nucleic acids research · 2007 · 7 claims · 6 setups

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  U1 snRNAs complementary to 5 of 15 targeted conserved regions in the HIV-1 terminal exon significantly suppress HIV-1 protein expression and viral replication, coincident with loss of viral RNA

  hiv-1 293t hela bioinformatic western reporter

• Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1.

  PMID 17967058 · PMC2042017 · PLoS pathogens · 2007 · 8 claims · 8 setups

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  APOBEC3C is necessary and sufficient to induce G-to-A mutation in some HIV-1 strains despite Vif expression

  magi pbmc 293t supt1 sensitive rt-pcr western

• Genetic diversity among Enterococcus faecalis.

  PMID 17611618 · PMC1899230 · PloS one · 2007 · 7 claims · 7 setups

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  Virulence and antibiotic resistance traits are distributed across many diverse E. faecalis lineages rather than confined to one clade

  faecalis multi-locus dot pcr

• Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristics.

  PMID 17331236 · PMC1868942 · Genome biology · 2007 · 8 claims · 8 setups

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  moDCs and KG-1 cells show significant proteomic differences from primary mDCs, particularly in proteins involved in cell growth/maintenance and cell-cell interaction/integrity.

  mdcs mdc freshly peripheral two-dimensional maldi-tof capture

• YAP1 Dysfunction Promotes Molecular Properties Linked to Breast Cancer Susceptibility.

  PMID 41431390 · PMC13040214 · Cancer prevention research (Philadelphia, Pa.) · 2026 · 7 claims · 8 setups

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  YAP1 nuclear localization and mRNA expression significantly increase in luminal epithelial cells (LEp) with increased age and with genetic risk for breast cancer (e.g., BRCA1/2 mutation carriers)

  breast hmec post-stasis 184d-p16sh ihc bulk odds

• Development of a split-toxin CRISPR screening platform to systematically identify regulators of human myoblast fusion.

  PMID 41540035 · PMC12808753 · Nature communications · 2026 · 8 claims · 7 setups

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  A CRISPR screening platform combining human myoblast models, a custom muscle-targeted gRNA library (MyoCRISPR-KO Lib), and a split-toxin selection system enables quantitative enrichment of fusion-defective myocytes.

  myoblasts myoblast time-course immunostaining gene

• Glutamine-mediated crosstalk between M2 macrophages and tumor cells via the SLC38A5/FOXM1/CNIH4 axis promotes oral squamous cell carcinoma progression.

  PMID 41715179 · PMC13020291 · Journal of translational medicine · 2026 · 8 claims · 8 setups

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  Glutamine secretion from M2 macrophages to tumor cells via SLC38A5 is the core mCCC pathway upregulated in metastatic OSCC lesions compared to primary lesions.

  oscc epithelial tcga-oscc hsc-3 scrna-seq hdwgcna bulk

• Smoking-induced dysregulation of transposable elements in the small airway epithelium.

  PMID 41845375 · PMC13107634 · Respiratory research · 2026 · 8 claims · 6 setups

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  Cigarette smoking dysregulates TE expression in the SAE, with 191 upregulated and 111 downregulated TE compared to nonsmokers

  sae hsabci-ns1.1 bulk single-cell te-gene

• KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.

  PMID 41907411 · PMC13018899 · iScience · 2026 · 8 claims · 8 setups

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  A malignant epithelial subpopulation (Cluster 0) with the highest CytoTRACE stemness potential and highest EMT activity exists in ESCC scRNA-seq data

  escc degs eca109 kyse180 scrna-seq machine immunohistochemistry

• Interferon-γ selectively promotes survival of alveolar progenitor cells in a human lung organoid model.

  PMID 41992061 · PMC13187038 · The EMBO journal · 2026 · 8 claims · 7 setups

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  A new human ALVO model supports long-term expansion of alveolar progenitor cells and defined serum-free differentiation into AT1-like cells, improving on prior HTII-280-selection/serum-based protocols

  alvos organoid-derived sorted viability scrna-seq immunofluorescence