Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation.
PMID 19903857 · PMC2973841 · Cancer research · 2009 · 8 claims · 8 setups
S1P2−/− mice develop clonal B-cell lymphomas with age, with ~half affected by 1.5-2 years
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Estimating the impact of reopening schools on the reproduction number of SARS-CoV-2 in England, using weekly contact survey data.
PMID 34503493 · PMC8428960 · BMC medicine · 2021 · 8 claims · 6 setups
Reopening all schools under lockdown-equivalent conditions would likely substantially increase the reproduction number of SARS-CoV-2
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Transposable elements are driving rapid adaptation of Enterococcus faecium.
PMID 42020750 · PMC13216065 · Nature · 2026 · 8 claims · 8 setups
E. faecium has the highest IS density among ESKAPEE pathogens, dominated by replicative ISL3 family elements
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Putting science over supposition in the arena of personalized genomics.
PMID 18665132 · PMC2531214 · Nature genetics · 2008 · 6 claims · 3 setups
There is a rapidly widening gap between gene-disease association discovery and research into the public health/clinical utility of that information.
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Has reproduction · 75
PHA4GE quality control contextual data tags: standardized annotations for sharing public health sequence datasets with known quality issues to facilitate testing and training.
PMID 38860884 · PMC11261899 · Microbial genomics · 2024 · 7 claims · 4 setups
No standardized attributes or mechanisms existed for tagging poor-quality or purpose-specific pathogen sequence datasets prior to this work
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Has reproduction
The role of the multidisciplinary health care team in the management of patients with Marfan syndrome.
PMID 27843325 · PMC5098778 · Journal of multidisciplinary healthcare · 2016 · 8 claims · 1 setups
A multidisciplinary health care team is a means to maximize therapeutic success for patients with Marfan syndrome (MFS)
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Genomics and public health: development of Web-based training tools for increasing genomic awareness.
PMID 15888236 · PMC1327719 · Preventing chronic disease · 2005 · 7 claims · 4 setups
Web-based training tools (Genomics for Public Health Practitioners and Six Weeks to Genomic Awareness) can increase genomic awareness among public health practitioners nationwide.
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Functional classification using phylogenomic inference.
PMID 16846248 · PMC1484587 · PLoS computational biology · 2006 · 8 claims · 1 setups
Functional annotation via top-hit database search transfer is used far more often in practice than phylogenomic inference, despite phylogenomic inference being more accurate.
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GenBank.
PMID 17202161 · PMC1781245 · Nucleic acids research · 2007 · 8 claims · 1 setups
GenBank is a comprehensive public database of nucleotide sequences with supporting bibliographic and biological annotation, built and distributed by NCBI
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Utah's Family High Risk Program: bridging the gap between genomics and public health.
PMID 15888235 · PMC1327718 · Preventing chronic disease · 2005 · 8 claims · 6 setups
Collection of family history through the Family High Risk Program (FHRP) is a cost-effective method for identifying and intervening with high-risk populations for chronic disease
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A virtual computer lab for distance biomedical technology education.
PMID 18366629 · PMC2292716 · BMC medical education · 2008 · 6 claims · 4 setups
A 'virtual computer lab' combining videoconferencing with VNC-based desktop sharing can replicate the functionality of a physical computer lab for distance biomedical technology education
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Helicobacter Pylori's plasticity zones are novel transposable elements.
PMID 19727398 · PMC2731543 · PloS one · 2009 · 8 claims · 8 setups
Plasticity zones are a novel class of transposable elements (named TnPZs), flanked by direct repeats of 5'AAGAATG and inserted at multiple discrete chromosomal sites
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Undergraduate research. Genomics Education Partnership.
PMID 18974335 · PMC2953277 · Science (New York, N.Y.) · 2008 · 6 claims · 4 setups
A course-embedded, multi-institution undergraduate research model (the Genomics Education Partnership) can deliver authentic research experiences during the academic year rather than only in summer programs.
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Comparative genomics of vertebrate Fox cluster loci.
PMID 17062144 · PMC1634998 · BMC genomics · 2006 · 8 claims · 3 setups
Two additional human paralogous Fox cluster regions exist, on chromosomes 14 and 20, beyond the previously known chromosome 6 and 16 loci
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Changes in social contacts in England during the COVID-19 pandemic between March 2020 and March 2021 as measured by the CoMix survey: A repeated cross-sectional study.
PMID 35231023 · PMC8887739 · PLoS medicine · 2022 · 8 claims · 2 setups
Recorded social contacts in England decreased dramatically compared to prepandemic levels measured by the POLYMOD study
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Has reproduction · 91
Genome-wide identification of conserved and novel microRNAs in one bud and two tender leaves of tea plant (Camellia sinensis) by small RNA sequencing, microarray-based hybridization and genome survey scaffold sequences.
PMID 29157210 · PMC5697157 · BMC plant biology · 2017 · 8 claims · 8 setups
175 conserved miRNAs (39 families) and 83 novel miRNAs were identified in C. sinensis one bud and two tender leaves using small RNA sequencing combined with genome survey scaffold data
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Improved methods for the enrichment and analysis of glycated peptides.
PMID 18989935 · PMC2752342 · Analytical chemistry · 2008 · 7 claims · 4 setups
Replacing off-line desalting with an online 50 mM NH4OAc wash (10 min) of boronate-bound glycated proteins improves the enrichment workflow while minimizing sample loss
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Has reproduction · 57
Environmental selection overturns the decay relationship of soil prokaryotic community over geographic distance across grassland biotas.
PMID 35073255 · PMC8828049 · eLife · 2022 · 8 claims · 7 setups
Prokaryotic community similarity follows a significant U-shape relationship over geographic distance up to 4000 km, decreasing within biotas but increasing across biotas after a tipping point of 1760-1920 km
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Blood Pressure Sunday: introducing genomics to the community through family history.
PMID 15888234 · PMC1327717 · Preventing chronic disease · 2005 · 7 claims · 5 setups
Family history is a significant, longstanding risk factor for high blood pressure and can serve as a practical 'genomic tool' for public health given that routine DNA-based risk testing is not yet available.
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Animal models of gene-nutrient interactions.
PMID 19037208 · PMC2703433 · Obesity (Silver Spring, Md.) · 2008 · 8 claims · 5 setups
Mice and rats are well-suited models for human food selection because they share food preferences with humans and are supported by extensive genetic tools (sequenced genome, inbred strains, gene targeting, Cre-lox).