Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers.
PMID 19671847 · PMC2892178 · Clinical cancer research : an official journal of the American Association for Cancer Research · 2009 · 8 claims · 5 setups
Genomic profiling by aCGH can distinguish clonal tumors from independent primaries with high confidence by identifying matching versus non-matching regions of allelic gain/loss.
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A chromosome-level reference genome and pangenome for barn swallow population genomics.
PMID 36662619 · PMC10044405 · Cell reports · 2023 · 8 claims · 8 setups
A chromosome-level, karyotype-validated reference genome (bHirRus1) was assembled using the VGP pipeline combining PacBio CLR, 10x Linked-Reads, Bionano optical maps, and Hi-C data
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Epidemiology and phylogenomic characterization of the Clade IIb C.1 Mpox outbreak in Phnom Penh, Cambodia (2023-2024).
PMID 41575511 · PMC12978180 · Emerging microbes & infections · 2026 · 8 claims · 8 setups
All Cambodian Mpox genomes belong to lineage C.1, nested within Clade IIb
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WeavePop: a bioinformatics workflow to explore and analyze genomic variants of eukaryotic populations.
PMID 41685638 · PMC13042275 · G3 (Bethesda, Md.) · 2026 · 8 claims · 7 setups
WeavePop is a novel Snakemake-based, reproducible, scalable workflow that performs reference-based read mapping, assembly, annotation, small variant calling/effect prediction, and CNV detection for eukaryotic haploid organisms
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The Genetic Architecture of Venom Resistance: A Novel Approach to Target Identification and Coevolutionary Discovery.
PMID 41739857 · PMC12978544 · Molecular biology and evolution · 2026 · 8 claims · 5 setups
12 consensus candidate genes were identified across E&R and XQTL techniques as associated with venom resistance
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PDA: Pooled DNA analyzer.
PMID 16643673 · PMC1539032 · BMC bioinformatics · 2006 · 8 claims · 4 setups
No software existed prior to PDA for complete pooled-DNA analysis including data standardization, allele frequency estimation, and single/multipoint association tests
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Has reproduction · 56
Profiling Selective Packaging of Host RNA and Viral RNA Modification in SARS-CoV-2 Viral Preparations.
PMID 35186917 · PMC8851031 · Frontiers in cell and developmental biology · 2022 · 8 claims · 3 setups
SARS-CoV-2 viral preparations show selective enrichment of specific host tRNAs, tRNA fragments, and SRP RNA compared to uninfected VeroE6 cells
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Mutational analysis of the PITX2 coding region revealed no common cause for transposition of the great arteries (dTGA).
PMID 15890066 · PMC1142516 · BMC medical genetics · 2005 · 7 claims · 3 setups
Screening of the PITX2 coding region and exon-intron junctions in 96 dTGA patients revealed no stop or frameshift mutations.
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TassDB: a database of alternative tandem splice sites.
PMID 17142241 · PMC1669710 · Nucleic acids research · 2007 · 7 claims · 3 setups
TassDB is a relational database storing GYNGYN donor and NAGNAG acceptor tandem splice sites across eight species
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Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer.
PMID 17700570 · PMC2360390 · British journal of cancer · 2007 · 8 claims · 3 setups
Germline protein-truncating BRCA2 mutations confer an elevated relative risk (~7.8-fold) of early-onset prostate cancer in Caucasian men
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Decoding of superimposed traces produced by direct sequencing of heterozygous indels.
PMID 18654614 · PMC2429969 · PLoS computational biology · 2008 · 7 claims · 3 setups
A dynamic programming method (implemented as web app Indelligent) can decode superimposed allelic sequences from a single mixed trace, using only the observed string of ambiguous peak calls, without a reference sequence or reverse trace.
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Genome Wide Association Studies: identifying the genes that determine the risk of abdominal aortic aneurysm.
PMID 18621558 · PMC2697027 · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2008 · 8 claims · 3 setups
AAA has a strong genetic component, with up to ten-fold increased risk in first-degree relatives of affected individuals
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BOAT: Basic Oligonucleotide Alignment Tool.
PMID 19958483 · PMC2788372 · BMC genomics · 2009 · 7 claims · 3 setups
BOAT can accurately and efficiently map sequencing reads to a reference genome while handling several substitutions and indels simultaneously
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Has reproduction · 85
Ensembl 2013.
PMID 23203987 · PMC3531136 · Nucleic acids research · 2013 · 8 claims · 8 setups
Ensembl (http://www.ensembl.org) provides genome information for sequenced chordate genomes, currently supporting 70 species with a focus on human, mouse, zebrafish and rat.
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Twin peaks: the draft human genome sequence.
PMID 11276423 · PMC138909 · Genome biology · 2001 · 8 claims · 8 setups
The predicted number of human genes (~26,000-40,000) is far lower than the widely assumed ~100,000, though downstream RNA/protein complexity can still generate substantial biological complexity.
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Ensembl 2006.
PMID 16381931 · PMC1347495 · Nucleic acids research · 2006 · 8 claims · 5 setups
Ensembl now provides annotation for 19 genomes, up from 4 the previous year, including new mammalian (Rhesus macaque, Opossum), chordate (Ciona intestinalis), and yeast genomes.
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MitoVariome: a variome database of human mitochondrial DNA.
PMID 19958475 · PMC2788364 · BMC genomics · 2009 · 8 claims · 5 setups
MitoVariome is a web-based, integrated variome database for human mitochondrial DNA that unifies sequence variation, haplogroup, and disease annotation information not jointly available in prior databases (MITOMAP, mtDB, Mitome, MitoRes).
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Has reproduction · 79
Decoding and reconstructing disease relations between dry eye and depression: a multimodal investigation comprising meta-analysis, genetic pathways and Mendelian randomization.
PMID 38548265 · PMC11954816 · Journal of advanced research · 2025 · 8 claims · 8 setups
Meta-analysis confirmed a positive association between DED and DEP occurrence
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Has reproduction
Molecular Epidemiology of Invasive Group B Streptococcus in South Africa, 2019-2020.
PMID 39737783 · PMC11998550 · The Journal of infectious diseases · 2025 · 8 claims · 6 setups
Invasive GBS isolates in South Africa belong to 5 clonal complexes (CC1, CC8/10, CC17, CC19, CC23) and 6 serotypes (III, Ia, V, II, Ib, IV)
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Has reproduction · 49
LRP1 as a potential diagnostic and immunomodulatory target in endometriosis: evidence from multi-omics and single-cell analyses.
PMID 42064072 · PMC13124487 · Frontiers in immunology · 2026 · 8 claims · 8 setups
LRP1 is a hub gene with the highest diagnostic performance among 30 candidate hub genes identified by machine learning