Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 495

System / cell line: western ✕ Clear

A novel gammaD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract.

PMID 19668596 · PMC2722711 · Molecular vision · 2009 · 8 claims · 6 setups

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A novel heterozygous CRYGD mutation c.43C>A (R15S) causes congenital coralliform cataract in Family A

family genomic crygd lens two-point microsatellite direct
Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.

PMID 39775580 · PMC11684664 · PloS one · 2024 · 7 claims · 8 setups

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MitoDEGs in MI are mainly involved in mitochondrial function and ATP synthesis pathways

left mus combined heart microarray weighted bulk
PPDPF is not a key regulator of human pancreas development.

PMID 40193385 · PMC12037078 · PLoS genetics · 2025 · 8 claims · 8 setups

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PPDPF is not a key regulator of human pancreas development, in contrast to its zebrafish orthologue exdpf

fetuses fetal hesc population situ proteome qpcr
Elevated phenylacetylglutamine caused by gut dysbiosis associated with type 2 diabetes increases neutrophil extracellular traps formation and exacerbates brain infarction.

PMID 40471587 · PMC12599254 · Clinical science (London, England : 1979) · 2025 · 7 claims · 8 setups

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Plasma PAGln levels are significantly higher in ischemic stroke patients with T2D than in those without T2D

fecal plasma sprague-dawley cerebral 16s metagenome targeted
LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture.

PMID 41489510 · PMC13040219 · Cancer discovery · 2026 · 8 claims · 8 setups

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LINE-1 RNAs are primarily chromatin-associated nascent transcripts rather than cytosolic mRNAs

mcf7 cancer qrt-pcr single-molecule chirp-seq
Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi.

PMID 41628159 · PMC12863538 · PLoS biology · 2026 · 8 claims · 8 setups

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In M. bainieri, most (90%) FK506-resistant isolates are unstable/transient and revert to drug sensitivity without any detectable DNA mutation

mucor fk506-resistant bainieri drug sanger serial
The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer.

PMID 41202211 · PMC12768431 · Cancer research · 2026 · 8 claims · 8 setups

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Organismal aging accelerates PDAC progression and metastatic burden in an age-relevant syngeneic orthotopic mouse model

kpc4662 orthotopic pdac pancreatic orthotopic heterochronic ultrasound
Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia.

PMID 41270153 · PMC7618455 · Cancer research · 2026 · 8 claims · 8 setups

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ReSisTrace single-cell lineage tracing identifies pre-resistant and pre-sensitive cell states to FLT3 inhibitors midostaurin and quizartinib in FLT3-ITD-positive MOLM-13 AML cells before treatment

molm-13 aml-pdx1 single-cell lineage gene
Tight junction-high and CDH17-positive cell population is the source of colorectal cancer liver metastases.

PMID 41484106 · PMC12881549 · Nature communications · 2026 · 8 claims · 8 setups

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Loss/inhibition of IKKα unexpectedly promotes, rather than suppresses, CRC liver metastasis in patient-derived organoid (PDO) xenograft models.

pdo5 pdo5-derived crc dld1 intrasplenic immunohistochemistry kaplan-meier
TGFβ induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis.

PMID 41492090 · PMC12858408 · Nature cancer · 2026 · 7 claims · 8 setups

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TGFβ initially induces a full, typical EMT (stress fibers, loss of epithelial markers, motility) in dormancy-competent LUAD progenitors that subsequently transitions into an atypical spheroidal mesenchymal state lacking actin stress fibers.

h2087-lcc m802t4-lcc reconstructed immunofluorescence antibody-mediated
Multimodal epigenetic and enhancer network remodeling shape the transcriptional landscape of human beige adipocytes.

PMID 41501500 · PMC12881478 · Communications biology · 2026 · 8 claims · 8 setups

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The white adipocyte transcriptional program is tightly linked to promoter-level modulation of H3K27ac and chromatin accessibility.

adipose asc-derived white ascs bulk atac-seq chip-seq
Immuno-metabolic dysregulation in type 2 diabetes is associated with altered neutrophil functional plasticity, mitochondrial dysfunction, and compromised responses in sepsis.

PMID 41520116 · PMC12882159 · Journal of translational medicine · 2026 · 8 claims · 8 setups

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Proportions of functionally restricted neutrophil subpopulations (phagocytosis-only vs NETosis-only) are significantly altered in T2D and fail to elicit an immune response upon sepsis induction

peripheral bone plasma neutrophils flow bulk global
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.

PMID 33440156 · PMC8240962 · Cell reports · 2021 · 8 claims · 8 setups

Has reproduction

Endogenous fatty acid synthesis (DNL), regulated by ChREBP, is the central driver of BAT whitening/involution at thermoneutrality.

bat fatty lipidomics qpcr
Report of the 9th HLPP Workshop October 2007, Seoul, Korea.

PMID 18683817 · PMC4601560 · Proteomics · 2008 · 8 claims · 8 setups

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An integrated separating-identifying platform identified 6788 proteins (≥2 peptides, 95% confidence) in Chinese human liver samples, including 3721 new to liver and 977 hypothetical proteins

chinese liver hbv-related mammalian shotgun transcriptome yeast
Alternative splicing of human peroxisome proliferator-activated receptor delta (PPAR delta): effects on translation efficiency and trans-activation ability.

PMID 17705821 · PMC2045109 · BMC molecular biology · 2007 · 8 claims · 8 setups

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Multiple alternatively spliced 5'-UTR isoforms of human PPARdelta mRNA differ in translation efficiency

placenta five lines huh7 5'-race rt-pcr real-time

Experiments

A novel gammaD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract.

Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.

PPDPF is not a key regulator of human pancreas development.

Elevated phenylacetylglutamine caused by gut dysbiosis associated with type 2 diabetes increases neutrophil extracellular traps formation and exacerbates brain infarction.

LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture.

Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi.

The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer.

Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia.

Tight junction-high and CDH17-positive cell population is the source of colorectal cancer liver metastases.

TGFβ induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis.

Multimodal epigenetic and enhancer network remodeling shape the transcriptional landscape of human beige adipocytes.

Immuno-metabolic dysregulation in type 2 diabetes is associated with altered neutrophil functional plasticity, mitochondrial dysfunction, and compromised responses in sepsis.

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.

Report of the 9th HLPP Workshop October 2007, Seoul, Korea.

Alternative splicing of human peroxisome proliferator-activated receptor delta (PPAR delta): effects on translation efficiency and trans-activation ability.