Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming.
PMID 41606307 · PMC12945694 · Nature metabolism · 2026 · 8 claims · 8 setups
Lamin A/C represses cysteine biosynthesis and catabolism in naive mES cells by suppressing CTH and CBS
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Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.
PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups
The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.
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Cis-regulatory evolution reveals sensory trade-offs as a genetic basis for temporal niche evolution in tapirs.
PMID 41779860 · PMC12959415 · Science advances · 2026 · 8 claims · 8 setups
Tapirs reverted from a cathemeral ancestor to a nocturnal/crepuscular niche, accompanied by coordinated sensory reallocation: regressive vision (corneal opacity, reduced acuity) with enhanced auditory and chemosensory systems.
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ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.
PMID 41800619 · PMC13171160 · Cell reports · 2026 · 8 claims · 8 setups
Human ADAR1 downregulates self-dsRNA abundance through both editing-dependent and editing-independent mechanisms