Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Placental proteomics: a shortcut to biological insight.
PMID 19070895 · PMC3532024 · Placenta · 2009 · 7 claims · 5 setups
Developed a novel small cationic colloidal silica (smCCS) method to uniformly enrich the apical plasma membrane of the syncytiotrophoblast (STB) for proteomics analysis
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Tubulin proteomics: towards breaking the code.
PMID 18840397 · PMC4039029 · Analytical biochemistry · 2009 · 8 claims · 8 setups
Tubulin isotype and posttranslational-modification diversity constitutes a 'tubulin code' that is read by microtubule-associated proteins and translates into specific in vivo functions
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The clinical course and genetic defect in the PCFT gene in a 27-year-old woman with hereditary folate malabsorption.
PMID 18718264 · PMC3835188 · The Journal of pediatrics · 2008 · 6 claims · 5 setups
The patient carries two identical homozygous mutations (GC>AA at positions 197/198) in exon 1 of PCFT, causing a premature stop codon (C66X)
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'Unknown' proteins and 'orphan' enzymes: the missing half of the engineering parts list--and how to find it.
PMID 20001958 · PMC3022307 · The Biochemical journal · 2009 · 8 claims · 8 setups
Comparative genomics is the single most effective strategy for predicting functions of unknown proteins and finding genes for orphan enzymes
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C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.
PMID 19997494 · PMC2778949 · PLoS pathogens · 2009 · 8 claims · 8 setups
The C-terminal helix of apoL1 is entirely responsible for its interaction with SRA
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Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction.
PMID 12962547 · PMC212256 · BMC bioinformatics · 2003 · 8 claims · 3 setups
RMA-generated gene expression values are markedly less variable and more reliable than MAS5.0- and MBEI-derived values
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Microbial genomics: from sequence to function.
PMID 10998380 · PMC2627950 · Emerging infectious diseases · 2000 · 8 claims · 4 setups
Whole-genome shotgun sequencing (sequencing and assembly of random genome fragments), first demonstrated with Haemophilus influenzae in 1995, is now the method of choice for sequencing most genomes, including the human genome.
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An online database for brain disease research.
PMID 16594998 · PMC1489945 · BMC genomics · 2006 · 7 claims · 5 setups
SMRIDB is a comprehensive web-based database integrating gene expression data and clinical metadata to aid understanding of the genetic effects of brain disease (bipolar disorder, schizophrenia, depression)
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Has reproduction · 85
Taxonomic and functional partitioning of Chloroflexota populations under ferruginous conditions at and below the sediment-water interface.
PMID 39384533 · PMC11650866 · FEMS microbiology ecology · 2024 · 8 claims · 8 setups
Chloroflexota populations are partitioned according to alternative electron acceptors (Anaerolineae) and electron donors (Dehalococcoidia) among respiratory and fermentative metabolites at and below the sediment-water interface
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Has reproduction · 39
Glacier shrinkage will accelerate downstream decomposition of organic matter and alters microbiome structure and function.
PMID 35320603 · PMC9323552 · Global change biology · 2022 · 8 claims · 7 setups
Glacier shrinkage (decreasing glacier influence) accelerates downstream organic matter decomposition rates in glacier-fed streams
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Has reproduction · 55
Environment and Co-occurring Native Mussel Species, but Not Host Genetics, Impact the Microbiome of a Freshwater Invasive Species (Corbicula fluminea).
PMID 35444631 · PMC9014210 · Frontiers in microbiology · 2022 · 7 claims · 7 setups
The gut microbiome of C. fluminea is diverse, differs with environmental conditions, and varies spatially among rivers, but is unrelated to host genetic variation
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Has reproduction · 54
Oxidative stress protection and growth promotion activity of Pseudomonas mercuritolerans sp. nov., in forage plants under mercury abiotic stress conditions.
PMID 36560952 · PMC9763275 · Frontiers in microbiology · 2022 · 8 claims · 8 setups
Inoculation with SAICEUPSM^T significantly reduces the oxidative stress enzymatic response (CAT, APX, SOD, GR) in Lupinus albus grown under mercury stress
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Has reproduction · 72
Temporal trends in methane emissions from a small eutrophic reservoir: the key role of a spring burst.
PMID 35126532 · PMC8815417 · Biogeosciences (Online) · 2021 · 8 claims · 7 setups
Acton Lake had cumulative areal CH4 emission rates of 45.6 ± 8.3 g CH4 m-2 in 2017 and 51.4 ± 4.3 g CH4 m-2 in 2018 (109 ± 14 and 123 ± 10 Mg CH4 whole-reservoir, respectively)
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Has reproduction · 95
Spatial patterns of benthic biofilm diversity among streams draining proglacial floodplains.
PMID 36003939 · PMC9393633 · Frontiers in microbiology · 2022 · 7 claims · 8 setups
Benthic biofilms in tributaries develop higher biomass than those in glacier-fed streams along the lateral chronosequence
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Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties.
PMID 15804357 · PMC1129089 · BMC genomics · 2005 · 8 claims · 6 setups
MagT1 is a novel mammalian Mg2+ transporter with channel-like properties, showing no amino acid sequence identity to other known transporters
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Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry.
PMID 17166507 · PMC7094463 · Journal of chromatography. A · 2007 · 8 claims · 8 setups
Standardizing sample preparation procedures for serum/plasma profiling is critical for obtaining reliable biomarkers, since slight procedural changes can produce very different protein profiles.
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Gene and transcript abundances of bacterial type III secretion systems from the rumen microbiome are correlated with methane yield in sheep.
PMID 28789673 · PMC5549432 · BMC research notes · 2017 · 7 claims · 7 setups
Gene and transcript abundances of bacterial type III secretion system (T3SS) genes are positively correlated with methane yield in sheep
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Seasonal Dynamics Are the Major Driver of Microbial Diversity and Composition in Intensive Freshwater Aquaculture.
PMID 34248892 · PMC8264503 · Frontiers in microbiology · 2021 · 7 claims · 6 setups
Natural seasonality is the primary driver of aquatic bacterial community structure in the fishponds and reservoir
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metaTraits: a large-scale integration of microbial phenotypic trait information.
PMID 41296543 · PMC12807735 · Nucleic acids research · 2026 · 8 claims · 6 setups
metaTraits integrates culture-derived trait data from BacDive, BV-BRC, JGI IMG, and GOLD with genome-based predictions for isolate genomes (proGenomes) and MAGs (SPIRE)