Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• AMR-GNN: a multi-representation graph neural network framework to enable genomic antimicrobial resistance prediction.

  PMID 41792137 · PMC13087051 · Nature communications · 2026 · 7 claims · 8 setups

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  AMR-GNN, a graph neural network integrating multiple genomic representations (unitigs, SNPs, FCGR) via low-rank multimodal fusion, improves AMR phenotype prediction in P. aeruginosa compared to single-representation baseline models.

  pseudomonas aeruginosa escherichia coli whole-genome elastic convolutional

• Dual-platform metagenomic surveillance distinguishes pathogen and resistome hotspots across agricultural and mixed-use watersheds.

  PMID 41890980 · PMC13015239 · One health (Amsterdam, Netherlands) · 2026 · 8 claims · 7 setups

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  Agricultural drainage ditches consistently harbor higher fecal-associated bacterial diversity than mixed-use or forested sites, with pronounced seasonal shifts (higher during spring/fall high-flow periods).

  surface shotgun trimmed co-assembled 16s shotgun short-read

• BaGPipe: an automated, reproducible, and flexible pipeline for bacterial genome-wide association studies.

  PMID 41896736 · PMC13147680 · BMC microbiology · 2026 · 7 claims · 8 setups

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  BaGPipe is an automated, reproducible Nextflow pipeline that integrates pre-processing, Pyseer-based association analysis, and downstream visualisation into a unified bacterial GWAS workflow

  streptococcus staphylococcus aureus pneumoniae bacterial read amr

• Diversity and evolution of a phase-variable multi-locus antigen in Neisseria gonorrhoeae.

  PMID 42113870 · PMC13183285 · PLoS pathogens · 2026 · 8 claims · 8 setups

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  Each N. gonorrhoeae genome has on average 7 distinct opa alleles at 9-12 opa loci

  gonorrhoeae complete opa non-gonorrhoeae long-read custom blast

• Taxonomic description of cyanobacteria from extreme habitats through genome-based classification.

  PMID 42131214 · PMC13161053 · Frontiers in microbiology · 2026 · 8 claims · 7 setups

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  Cyanobacteria dominate the microbial communities of Hawaiian steam vent habitats, with community composition varying by microhabitat

  environmental steam assembled cyanobacterial 16s metagenome genome

• Looping specificity of Polycomb response elements requires GAF and a combination of looping factors that could form a code.

  PMID 42206359 · PMC13216745 · Nucleic acids research · 2026 · 8 claims · 8 setups

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  High GAF occupancy is required for chromatin looping and gene regulation at PREs

  drosophila third gaf dac_tss cut&run micro-c hi-c

• Improved chromosome-level genome assembly of the American cockroach, Periplaneta americana.

  PMID 41123565 · PMC12774602 · G3 (Bethesda, Md.) · 2026 · 8 claims · 7 setups

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  Produced the first chromosome-level genome assembly of P. americana, scaffolded into 17 chromosome-scale scaffolds consistent with karyotype

  leg midgut assembled blattodea pacbio hi-c bulk

• High-quality genome assembly and annotation of the white-cheeked goby, Rhinogobius duospilus (Herre, 1935) (Gobiiformes: Oxudercidae).

  PMID 41248690 · PMC12869079 · G3 (Bethesda, Md.) · 2026 · 6 claims · 7 setups

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  This is the first high-quality chromosome-level reference genome for R. duospilus

  duospilus pacbio hi-c rna-seq

• CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions.

  PMID 41498638 · PMC12948241 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups

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  CellPolaris is a unified computational framework performing TF-centered GRN construction, master TF identification, and TF perturbation simulation

  bulk previously round paired transfer-learning cross-species

• Efficient recovery and DNA extraction for algae-associated microbial communities.

  PMID 41560914 · PMC12813104 · Frontiers in plant science · 2025 · 8 claims · 7 setups

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  A universal trade-off exists between the quantity and quality of DNA extracted from algal biofilm microbial communities.

  macroalgae extracted microbial biofilm confocal concentration spectrophotometry

• Redefinition of the toll-like receptor repertoire in Ciona robusta through genomic, structural, and expression analyses.

  PMID 41568004 · PMC12816324 · Frontiers in cellular and infection microbiology · 2025 · 8 claims · 8 setups

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  CiTLR13 is a redundant annotation of CiTLR1 (same genomic locus, >94% sequence identity), so it is not a distinct TLR gene

  ciona six lrr tlr blastp domain nucleotide

• Comparative multi-omic analysis reveals conserved and derived mechanisms of fin and limb regeneration.

  PMID 41571662 · PMC12923738 · Nature communications · 2026 · 8 claims · 8 setups

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  Fin and limb regeneration share conserved proximal and distal blastema territory markers, DNA damage repair activation, hif1a-mediated hypoxia response, and sequential pro-/anti-inflammatory gene programs.

  polypterus axolotl zebrafish regenerating single-nucleus spatial single-cell

• Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

  PMID 41649260 · PMC12880807 · eLife · 2026 · 8 claims · 8 setups

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  13LGS cone photoreceptors arise from both early-stage and late-stage neurogenic progenitors, unlike mice where cones arise only from early-stage progenitors

  13-lined retina 13lgs retinal single-cell scrna-seq chromvar

• Chromosome-scale genome assembly and annotation of the two-spotted cricket Gryllus bimaculatus (Orthoptera: Gryllidae).

  PMID 41678355 · PMC13042277 · G3 (Bethesda, Md.) · 2026 · 8 claims · 8 setups

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  A chromosome-scale genome assembly of the white-eyed mutant G. bimaculatus strain was generated using ONT + PacBio HiFi long reads integrated with Hi-C data

  bimaculatus nanopore pacbio hi-c

• Excitatory GABA receptors shape locomotor circuit organization in C. elegans.

  PMID 41703147 · PMC13003095 · Scientific reports · 2026 · 8 claims · 5 setups

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  lgc genes are broadly and preferentially enriched in C. elegans locomotion motor neurons compared to other neuron types/subgroups

  elegans cys-loop single-cell ucell multi-species

• Massively parallel reporter assay for mapping gene-specific regulatory regions at single-nucleotide resolution.

  PMID 41738738 · PMC12935429 · eLife · 2026 · 8 claims · 8 setups

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  LS-MPRA (BAC-based) and d-MPRA (systematic mutagenesis) are complementary methods for unbiased, high-resolution mapping of cis-regulatory modules.

  mus e14 retina candidate ls-mpra single-cell individual

• A disease model resource reveals core principles of tissue-specific cancer evolution.

  PMID 41741657 · PMC13149333 · Nature · 2026 · 8 claims · 8 setups

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  The Mouse Cancer Cell line Atlas (MCCA) is a broad-utility resource of 590 comprehensively characterized mouse cancer cell line models spanning 22 lineages and 46 disease types, accessible via a web portal (www.mcca.tum.de)

  mcca tumour immunocompetent paca whole-genome microscopy-based histopathology

• Benchmarking LLM-based agents for single-cell omics analysis.

  PMID 41742311 · PMC13064268 · Genome biology · 2026 · 8 claims · 8 setups

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  Introduces a comprehensive benchmarking evaluation system comprising an open-source agent platform, 18 evaluation metrics across four dimensions, and 50 real-world single-cell omics tasks

  agent single-cell spatial scatac-seq llm-agent scrna-seq spatial

• Chromosome-level genome assembly of the deep-sea solemyid bivalve Acharax haimaensis.

  PMID 41760692 · PMC13066446 · Scientific data · 2026 · 7 claims · 9 setups

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  A. haimaensis genome was assembled to chromosome level (4.27 Gb, scaffold N50 195.52 Mb, anchored to 22 chromosomes) using PacBio HiFi, Illumina, and Hi-C sequencing

  acharax haimaensis illumina pacbio hi-c

• Predicting FOX gene candidates for oxic nitrogen fixation using multi-omic machine learning and comparative bioinformatics.

  PMID 41764348 · PMC13056922 · Scientific reports · 2026 · 8 claims · 6 setups

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  Random Forest, XGBoost, and logistic regression classifiers can meaningfully differentiate literature-validated FOX genes from conserved non-essential genes, with Random Forest achieving the best ROC-AUC (~0.80)

  anabaena diazotrophic gene-level trained bulk quantitative transcription-start-site-derived