Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 49
oPOSSUM-3: advanced analysis of regulatory motif over-representation across genes or ChIP-Seq datasets.
PMID 22973536 · PMC3429929 · G3 (Bethesda, Md.) · 2012 · 8 claims · 6 setups
oPOSSUM-3 is a web-accessible system that identifies over-represented TFBS and TFBS families in DNA sequences of co-expressed genes or in sequences from high-throughput methods such as ChIP-Seq.
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We are the genes we've been waiting for: rational responses to the gathering storm of personal genomics.
PMID 19998110 · PMC3749831 · The American journal of bioethics : AJOB · 2009 · 8 claims · 5 setups
Medical establishment critics dismissed PGT information in 2008 as either not worth much or dangerous
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Immersive virtual environment technology: a promising tool for future social and behavioral genomics research and practice.
PMID 20183376 · PMC2829714 · Health communication · 2009 · 8 claims · 4 setups
IVET allows researchers to simultaneously maintain high experimental control and high mundane realism, unlike traditional research settings where these trade off against each other.
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Genetic divergence of hepatitis C virus: the role of HIV-related immunosuppression.
PMID 18769357 · PMC3071283 · Journal of acquired immune deficiency syndromes (1999) · 2008 · 7 claims · 6 setups
HIV coinfection is associated with ~0.5 log10 higher HCV RNA levels, suggesting increased HCV replication
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Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues.
PMID 20010552 · PMC2820137 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2010 · 6 claims · 4 setups
Carriers of the CNR1 rs2023239 G allele show significantly greater neural activation to marijuana cues than A/A homozygotes in reward-related regions (OFC, IFG, insula, ACG).
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MutDB: update on development of tools for the biochemical analysis of genetic variation.
PMID 17827212 · PMC2238958 · Nucleic acids research · 2008 · 7 claims · 5 setups
MutDB integrates dbSNP and Swiss-Prot genetic variation data with protein structural information, functional disruption prediction scores, and clinical phenotype links (OMIM, dbGAP)
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Processing and population genetic analysis of multigenic datasets with ProSeq3 software.
PMID 19797407 · PMC2778335 · Bioinformatics (Oxford, England) · 2009 · 8 claims · 7 setups
ProSeq3 is a program with a graphic user interface that simplifies preparation and basic population genetic analysis of multigenic DNA polymorphism datasets
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ADaCGH: A parallelized web-based application and R package for the analysis of aCGH data.
PMID 17710137 · PMC1940324 · PloS one · 2007 · 8 claims · 4 setups
ADaCGH implements eight CNA detection methods, including the best-performing ones from recent reviews (CBS, GLAD, CGHseg, HMM)
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SysPIMP: the web-based systematical platform for identifying human disease-related mutated sequences from mass spectrometry.
PMID 19036792 · PMC2686442 · Nucleic acids research · 2009 · 8 claims · 7 setups
SysPIMP is a web-based platform integrating disease mutation databases with X!Tandem and BLAST to identify disease-related mutated proteins from MS results
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Has reproduction
All of gene expression (AOE): An integrated index for public gene expression databases.
PMID 31978081 · PMC6980531 · PloS one · 2020 · 6 claims · 4 setups
ArrayExpress (AE) discontinued importing data from GEO in 2017, causing new GEO entries to become unavailable from AE
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Has reproduction · 78
GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning.
PMID 34461978 · PMC8407037 · Genome medicine · 2021 · 8 claims · 6 setups
GenTB is a free, open, web-based application offering two ML predictors (Random Forest and WDNN) that predict resistance to 13 and 10 anti-TB drugs, respectively.
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Has reproduction · 43
StatsDB: platform-agnostic storage and understanding of next generation sequencing run metrics.
PMID 24627795 · PMC3938176 · F1000Research · 2013 · 8 claims · 6 setups
StatsDB is an open-source software package for storage and analysis of next generation sequencing run metrics, backed by an SQL (MySQL) database with Perl and Java APIs.