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Prediction, syntax and semantic grounding in the brain and large language models.

Sci Rep · 2026
L1 86/100 3/4
Why this verdict

The main results reproduced: recomputed values matched the published ones within tolerance.

Reproduced on the brainbox compute brainarbeit.com
✓ What held up
  • No relevant deviation in data/preprocessing
  • Any deviation was negligible
What did not (or only partly)
  • 🟡Could not use the authors’ exact input data
  • 🟡Reported values were only indirectly comparable
  • 🟡A deviation was attributed to the published material
  • 🟡Reported values were not (fully) derivable from the shared data
  • 🟡The central claim did not (fully) hold under reproduction
  • 🟡Overall, the reproduction showed a material discrepancy
How its reproducibility compares
86/100
Reproducibility score
0.7 SD above mean
vs. all fields · 1173 studies
🎯 Scores higher than 70% of all assessed papers rank 334 of 1173 scored

A 0–100 reproducibility-quality score from the per-question grades, shown as a z-score: standard deviations above (+) or below (−) the mean of comparable assessments.

Reproduction agent’s raw note

Described well enough for ONE result, blocked for the rest. EXACT 1:1 reproduction of Fig 1E word-class counts (NOUN 1376, VERB 936, ADJ 325, PROPN 413, total 3050) by counting the spaCy POS labels shipped in the repo's Excels/*_wordclass.xlsx across all 20 analyzed audiobook chapters (commit 7448078084ca, computed on «host» with Python stdlib, no GPU). These numbers are exactly recomputable from the released data -> fully grounded, no fabrication signal. The two Llama 3.2 analyses (Fig 8I semantic predictability; Fig 8K GDV + Fig 8M probe-classifier accuracy) could NOT be reproduced: both scripts require Transcript/{ch}_words.xlsx, the actual German audiobook words, which the README explicitly gates ('contact the authors'); the repo ships POS labels and numeric onsets only, so the LLM input text is data_restricted (the neural EEG/MEG .fif data IS open on Zenodo 15744486, but the text/audio is not). These figures also carry no numeric values in the text, so any comparison would be qualitative. The EEG/MEG neural contrasts (Figs 1-7) were NOT attempted: they are produced in the Brainstorm GUI (manual, non-scriptable), out of scope per the brief. Not a drop because a clearly-specified pipeline result reproduced exactly; not full because the headline LLM results depend on a restricted transcript. Brief's accession 10.5281/zenodo.1212303 does not resolve; used repo README's Zenodo 15744486 instead.

💻 Code ↗ 🗄 Data: 10.5281/zenodo.1212303

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Assessment versions

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  1. v1 current initial assessment Score 86
    assessed: 2026-06-16 ⛓ d03aa92aa836
✎ I am an author of this paper

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Provenance — full disclosure

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Reproduced
2026-06-16
Rubric version
v1.0
Assessed by
🤖 AI curator · claude (ai-curator room) · v1.0 · run #1 2026-06-16
no human curator yet
Last updated
2026-07-31

Provisional, curator- or AI-assessed, and independently checkable. A reproduction outcome states what one attempt could reproduce — not a judgement of the authors.

Deep full-text extraction

Model: opus
Founding hypothesis

How does the brain anticipate and process distinct word classes (nouns, verbs, adjectives, proper nouns) during naturalistic continuous speech comprehension, and do word-class-specific neural signatures of prediction and semantic grounding parallel the predictability and representational structure found in a transformer-based large language model (Llama 3.2)?

Core claims
  • Nouns show significant pre-onset neural activity, suggesting enhanced anticipatory processing of this word class. finding
  • Event-related fields and potentials for different word classes show highly reproducible, characteristic spatio-temporal signatures replicable across independent exploration and validation cohorts. finding
  • Source-space activity for nouns extends beyond temporal regions into sensorimotor cortices, suggesting deeper semantic grounding of nouns in sensory experience than verbs. finding
  • A linear probe on Llama 3.2 hidden states shows nouns and adjectives are more easily predicted than verbs, aligning with the pre-onset neural signals for nouns. finding
  • Combined simultaneous MEG-EEG recording leverages complementary sensitivities and high temporal resolution to capture spatio-temporal dynamics of anticipatory language processing. method
  • Comparing word-class-specific neural responses with word-class-specific predictability/representational structure in an LLM provides a complementary computational reference frame (rather than direct encoding/decoding mapping). method
  • Even neural networks trained only on next-word prediction can spontaneously internalize basic grammatical/word-type structure, supporting usage-based emergence of syntax. mechanism
  • Use of an exploration/validation cohort split as an internal replication strategy to enhance reproducibility of naturalistic EEG/MEG findings. method
Experimental setups
Assay System Perturbation Readout Platform
Magnetoencephalography (MEG), event-related fields during continuous speech listening 29 healthy right-handed German native speakers listening to German audio book 'Vakuum' none (naturalistic listening) word-class-specific ERFs (nouns, verbs, adjectives, proper nouns) around word onset 248-channel Magnes 3600WH, 4D-Neuroimaging
Electroencephalography (EEG), event-related potentials during continuous speech listening 29 healthy right-handed German native speakers listening to German audio book none (naturalistic listening) word-class-specific ERPs around word onset 64-channel ANT Neuro system (with EOG and ECG)
Source reconstruction (minimum norm imaging / sLORETA) of ERFs/ERPs human cortex template (ICBM 152 / MNI anatomy) none mean source activity per region across 600 Schaefer2018 parcellations, significant p-value source maps Brainstorm software; Overlapping Spheres (MEG), BEM/OpenMEEG (EEG)
Part-of-speech tagging of stimulus text German audio book transcript none POS tags assigning words to noun/verb/adjective/proper-noun classes spaCy model 'de_core_news_sm'
Linear probe neural network on LLM hidden states pre-trained multilingual Llama-3.2-1B (embedding layer + 16 transformer blocks) none word-class predictability / representational structure from hidden representations Llama-3.2-1B (release Sept 25, 2024), PyTorch, RoPE positional encoding
Forced alignment for word onset extraction audio files and corresponding transcripts none precise word onset times for epoching WebMAUS software
Key results
  • Significant pre-onset activity observed for nouns, indicating heightened anticipatory readiness for this word class
  • Word-class-specific ERF/ERP spatio-temporal signatures were highly reproducible across exploration and validation cohorts
  • Noun source activity extended into sensorimotor cortices beyond temporal regions, consistent with deeper semantic grounding than verbs
  • Linear probe of Llama 3.2 hidden states predicts nouns and adjectives more easily than verbs
  • Cluster-based and permutation tests revealed significant differences between noun and verb ERFs/ERPs (p < 0.05) p<0.05
Key statistics
  • count 29 participants (15 females) (study sample listening to audio book)
  • mean mean age 22.8 years (range 18-28) (participant age)
  • mean laterality quotient 85.4 ± 12.6 (right-handedness (Edinburgh-type))
  • count Nouns: 1376, Verbs: 936, Adjectives: 325, Proper Nouns: 413 (word-type frequency in audio book)
  • mean Noun word length µ:0.498 s σ:0.220 s (distribution of noun durations)
  • mean Verb word length µ:0.420 s σ:0.198 s (distribution of verb durations)
  • count exploration cohort subjects 1-19, validation cohort subjects 20-29 (internal replication split)
  • other 5,000 randomizations, two-tailed cluster-based/Wilcoxon tests, FDR corrected (statistical testing of ERF/ERP differences)

Statistical methods review

Model: sonnet

A neutral, descriptive read of the statistical approach — what was done, and (for shared learning, not as criticism) what could also have been done.

Twenty-nine participants listened to a naturalistic German audio book while simultaneous EEG and MEG were recorded. Neural responses were segmented by word class (nouns, verbs, adjectives, proper nouns) and analyzed via event-related fields and potentials (1–4 Hz filtered) in both sensor and source space. Primary inferential comparisons used cluster-based permutation tests (paired t-test and Wilcoxon signed-rank) against randomized baselines, with an FDR correction applied to the channel-level anticipatory analysis. A complementary analysis trained a linear probe on hidden states of Llama-3.2-1B to characterize word-class-level predictability in a large language model.

Replicationbiological Sample sizeN=29 total; divided chronologically into exploration (n=19) and validation (n=10) cohorts for internal replication; no formal a priori power analysis mentioned GroupsFour word classes (nouns, verbs, adjectives, proper nouns); primary inferential contrast is nouns vs. verbs; each class also compared to randomly selected baseline time points Pairingpaired Randomization/blindingnot stated DispersionSD Exact p-valuesno Effect sizesno Confidence intervalsno Multiplicity correctionFDR (method not further specified) for the Wilcoxon channel-level tests; cluster-based permutation inherently controls family-wise error across time and sensors for the t-test comparisons
Statistical tests used
Test Applied to n Assumptions
Cluster-based paired t-test (two-tailed, 5,000 randomizations) Sensor-space comparison of noun vs. verb ERFs/ERPs across all 29 participants and all channels/time points 29 participants not stated
Cluster-based permutation test / sourcestatistics (FieldTrip within Brainstorm) Source-space comparison of word-type-specific ERFs vs. randomly selected time points matched for trial number, across 600 Schaefer2018 parcellations 29 participants not stated
Two-tailed Wilcoxon signed-rank test (5,000 randomizations, FDR-corrected) Anticipatory activity analysis in predefined left frontal MEG channels and bilateral temporal EEG channels, comparing noun/verb ERPs/ERFs to random time points 29 participants not stated
Linear probe (single-layer neural network classifier) Word-class predictability from hidden states of Llama-3.2-1B across embedding and 16 transformer layers na
Approaches that could also have been used
  • The primary multi-channel, multi-timepoint comparison used cluster-based permutation testing, which controls family-wise error by treating contiguous clusters of significant time-sensor points as the unit of inference
    Could also: Mass-univariate testing with threshold-free cluster enhancement (TFCE) or FDR correction applied voxel-/sample-wise would also be standard in EEG/MEG research for this type of comparison — TFCE avoids the need to set an arbitrary cluster-forming threshold and can be more sensitive to spatially diffuse effects; FDR mass-univariate approaches similarly control for multiplicity while providing per-sample inference that can be easier to interpret
  • The cohort split (exploration n=19, validation n=10) was defined by chronological recording order, serving as an internal replication check
    Could also: Random assignment to the two cohorts, or a leave-one-out / k-fold cross-validation approach across subjects, could also be used to assess generalizability of grand-average patterns — Random splitting removes any potential confound of session order (e.g., equipment drift, seasonal variation in recruitment); cross-validation provides a continuous measure of how well patterns replicate rather than a binary exploration/validation outcome
  • Word-class effects on neural time series were analyzed at the level of grand-average ERPs/ERFs after collapsing across all tokens of each class per participant
    Could also: Linear mixed-effects models treating both participants and individual word tokens as random effects (the 'by-item' random slope, as recommended in Barr et al. 2013) would also be applicable — Mixed models account simultaneously for between-subject and between-item variability, and generalizability claims apply to both the sampled participants and the sampled vocabulary; averaging to the participant level before testing treats each token within a class as exchangeable
  • Source reconstruction used the standard ICBM 152 template MRI anatomy for all participants rather than individual structural MRIs
    Could also: Individual-MRI-based source reconstruction (with participant-specific BEM and cortical surface) is also standard when individual scans are available — Individual anatomy can improve co-registration accuracy and reduce spatial smearing in the source estimate, particularly for EEG where the skull and scalp geometry strongly influence the forward model; template-based methods are a well-accepted alternative when individual MRIs are not available
  • Neural results were reported as binary significance (p < 0.05) without accompanying effect sizes or confidence intervals
    Could also: Reporting Cohen's d (for paired differences), partial eta-squared, or 95% bootstrap confidence intervals around the cluster statistic or the mean difference waveform would also be standard — Effect size metrics and CIs communicate the magnitude and precision of differences independently of sample size, facilitating meta-analysis and sample-size planning for future studies; they are increasingly expected by journals and reporting guidelines (e.g., APA, OHBM)
  • The anticipatory analysis focused on a pre-selected set of left frontal MEG channels and bilateral temporal EEG channels, chosen a priori based on their relevance to language processing
    Could also: A whole-scalp permutation test with subsequent post-hoc channel-level inspection, or a data-driven approach using multivariate pattern analysis (MVPA) decoding across all sensors in the pre-onset window, could also characterize anticipatory topography — Pre-selection of channels based on prior knowledge is a valid and common approach; whole-scalp or MVPA approaches are complementary in that they allow discovery of anticipatory signals outside the a priori ROI and provide a continuous decoding accuracy time-course as an effect-size analogue
Software: MNE-Python 1.8.0 · WebMAUS (forced alignment) · spaCy (model: de_core_news_sm) · Brainstorm · FieldTrip toolbox (within Brainstorm) · PyTorch · Llama-3.2-1B release 2024-09-25

Citation network

Where this publication sits in the reproducibility-weighted citation graph — what it is built on, and what is built on it. Citation data from OpenAlex.

Citations
0
Impact: low
Foundation confidence
None of its references are in our reproducibility record yet — its foundation cannot be assessed.
Topics

No assessed neighbours yet — the network grows as more papers are assessed.

What was reproduced

The exact results taken into scope, with each reported value next to the value our attempt produced.

Scope — pmid-41807493

Paper: Kölbl et al. (2026) Prediction, syntax and semantic grounding in the brain and large language models. Sci Rep. PMID 41807493 / PMC12979642 / DOI 10.1038/s41598-026-41532-0.

Code: https://github.com/nikolakoe/Prediction_Syntax_Semantic_Grounding (commit 7448078084ca0aaaa99807f0cbba825af233e7b2, default branch main, public, MIT-less / no license file, Python).

Data: EEG/MEG recordings on Zenodo record 15744486 ("EEG/MEG recordings using german audio book", open access; ~33 subjects × ~750 MB preprocessed .fif plus raw EEG + stimuli channels). NOTE: the brief's listed accession 10.5281/zenodo.1212303 does not resolve; the repo README points to record 15744486, which is the live open dataset.

The pipeline (from README + scripts)

The authors recorded combined EEG+MEG while participants listened to ~1 h of the German sci-fi audiobook "Vakuum". Words were force-aligned (BAS WebMAUS), POS-classified with spaCy, the neural data epoched per word, statistics run in the Brainstorm GUI, and two LLM analyses (Llama 3.2) computed on the transcript.

# Reported result Pipeline In scope? Why
R1 Fig 1E word-class counts: NOUN 1376, VERB 936, ADJ 325, PROPN 413 (Σ 3050) spaCy POS tagging of transcript → counts YES Class labels are shipped in Excels/*_wordclass.xlsx (all 20 analyzed chapters). Reproducible from open data, no GPU, deterministic.
R2 Fig 8I semantic predictability per word class (Llama 3.2 next-word prob.) semantic_predictability_OpenAccess.py NO — blocked Script reads Transcript/{ch}_words.xlsx["Word"] = the actual German words. README: "For audio signals and transcript of the german audio book contact the authors." Transcript not shipped → data_restricted.
R3 Fig 8K GDV per Llama layer; Fig 8M probe-classifier accuracy per layer syntactic_predictability_OpenAccess.py NO — blocked Same: needs Llama hidden embeddings of each transcript word → requires the restricted transcript text. POS labels alone (shipped) are insufficient; the embeddings are the input.
R4 EEG/MEG neural contrasts (Figs 1–7) Brainstorm GUI statistical tests (README step 6) NO — out of scope Manual GUI analysis, not a scriptable pipeline. Preprocessing scripts (EEG/MEG) and epoching exist but produce intermediates, not a reported scalar; the reported neural stats are produced interactively in Brainstorm.

Decision

Reproduce R1 (the one clearly-specified, fully-open, pipeline-derived numeric result). R2/R3 are genuinely blocked by the restricted transcript text (the audio

  • transcript are "on request" even though the neural .fif data is open). R4 is a manual-GUI result, out of scope per the brief. Per the 80/20 rule we reproduce R1 exactly and document R2–R4 honestly rather than fabricate.

Verification that the transcript is genuinely absent

Excels/001_wordclass.xlsx (and all others) contains a single column Spacy holding POS tags only (X, ADP, NUM, NOUN, PROPN, PRON, AUX, DET, ADJ, VERB, ADV, CCONJ, PART, SCONJ, INTJ). No Word column / no German text. The companion *_Vakuum_word_boundaries.npy holds onsets (numbers), not words. So the words needed by the two Llama scripts are not derivable from the repo — consistent with the README's "contact the authors".

Figures / tables: Fig 1EFig 8IFig 8KFig 8MFigs
R1-NOUN
Reported
1376
Reproduced
1376
exact
R1-VERB
Reported
936
Reproduced
936
exact
R1-ADJ
Reported
325
Reproduced
325
exact
R1-PROPN
Reported
413
Reproduced
413
exact
R1-TOTAL
Reported
3050
Reproduced
3050
exact
R2-semantic-predictability
Reported
Fig 8I (no numeric text values)
Reproduced
partial
R3-gdv-and-probe-accuracy
Reported
Fig 8K / 8M (no numeric text values)
Reproduced
partial

Assessments & scoring basis

Each contributor’s verdict, the per-question basis, and the auditable, itemised worksheet behind it.

🤖 AI curator · claude (ai-curator room) · v1.0 L1 86/100

An automated assessment. It can flag an open question for review but can never, on its own, record a discrepancy verdict (C5) against a paper.

🟡1. Data identity
🟡2. Endpoint comparability
🟢3. Location of the main deviation
🟡4. Cause of the deviation
🟡5. Derivability / plausibility
🟢6. Severity of the deviation
🟡7. Core claim
🟡8. Severity of the miss (overall human judgment)
🤝
Reproduced automatically — and fairly

Automated reproduction checks whether a published result can be regenerated from the paper’s described methods and shared data. When something does not reproduce, that is not a claim of error or misconduct — most often it reflects under-described methods, software or environment differences, or gaps in data access, and some of the pre-print papers in the queue may carry issues their authors had no part in. The goal is shared awareness that rigorous, fully-described methods help everyone — never a judgement of any author.

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Reproduction footprint

claude-opus-4-8

Measured resources invested to assess this paper — sanitised (machine class only, no job ids/paths). Compute = HPC accounting (SLURM); tokens = the AI agent's session.

81.7 k
tokens (I/O) · 5.9 M incl. cache
10 min
runtime
Per-job HPC accounting not captured for this run — the runtime shown is the reproduction’s measured wall-clock time.