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Targeting the epigenome and the integrated stress response to normalize colorectal cancer subclonal plasticity and progression.
PMID 41963303 · Cell Death Dis · 2026
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Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia risk.
PMID 41796334 · Genome Biol · 2026
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68/100
ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
PMID 41820617 · EMBO J · 2026
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50/100
Population structure analysis of Salmonella serovar Muenchen to redefine geno-serotyping using genome indexing approaches.⚑
PMID 41743541 · Front Microbiol · 2026
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Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy.
PMID 41736854 · iScience · 2026
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Investigating epigenetic biomarkers of age, sex, and disease in captive South African cheetahs (Acinonyx jubatus jubatus).
PMID 41528985 · PLoS One · 2026
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Manual curation for improved genome annotation of the functionally extinct northern white rhinoceros (Ceratotherium simum cottoni).
PMID 41490125 · PLoS One · 2026
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Cell type- and species-specific regulation of hepatic lncRNAs by TCDD-activated aryl hydrocarbon receptor.
PMID 41136526 · Sci Rep · 2025
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Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues.
PMID 41162753 · EMBO J · 2025
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Caecilians maintain a functional long-wavelength-sensitive cone opsin gene despite signatures of relaxed selection and more than 200 million years of fossoriali⚑
PMID 40990923 · Evolution · 2025
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L-Arabinose Alters the E. coli Transcriptome to Favor Biofilm Growth and Enhances Survival During Fluoroquinolone Stress.
PMID 40732174 · Microorganisms · 2025
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Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population.
PMID 40258987 · Commun Biol · 2025
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Data-driven projections of candidate enhancer-activating SNPs in immune regulation.
PMID 40011812 · BMC Genomics · 2025
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RummaGEO: Automatic mining of human and mouse gene sets from GEO.
PMID 39569206 · Patterns (N Y) · 2024
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The Multi-State Epigenetic Pacemaker enables the identification of combinations of factors that influence DNA methylation.
PMID 39549198 · Geroscience · 2024
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Community assessment of methods to deconvolve cellular composition from bulk gene expression.
PMID 39191725 · Nat Commun · 2024
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Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers.
PMID 39183332 · Cell Death Dis · 2024
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Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter.
PMID 38587191 · Nucleic Acids Res · 2024
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The soil microbiome modulates the sorghum root metabolome and cellular traits with a concomitant reduction of Striga infection.
PMID 38537644 · Cell Rep · 2024
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Gbdmr: identifying differentially methylated CpG regions in the human genome via generalized beta regressions.⚑
PMID 38443825 · BMC Bioinformatics · 2024
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The identification of a Distinct Astrocyte Subtype that Diminishes in Alzheimer's Disease.
PMID 38502590 · Aging Dis · 2024
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Design of a targeted blood transcriptional panel for monitoring immunological changes accompanying pregnancy.
PMID 38352867 · Front Immunol · 2024
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Identification of herpesvirus transcripts from genomic regions around the replication origins.
PMID 37773348 · Sci Rep · 2023
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.
PMID 37572656 · Immunity · 2023
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Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use.
PMID 37218167 · Epigenetics · 2023
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Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature.
PMID 37076665 · NPJ Precis Oncol · 2023
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Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
PMID 36696508 · Sci Adv · 2023
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An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors.
PMID 36548438 · PLoS Comput Biol · 2022
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Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.
PMID 36450752 · Nat Commun · 2022
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Spatial transcriptomics demonstrates the role of CD4 T cells in effector CD8 T cell differentiation during chronic viral infection.
PMID 36450262 · Cell Rep · 2022
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CHD7 regulates otic lineage specification and hair cell differentiation in human inner ear organoids.
PMID 36396635 · Nat Commun · 2022
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Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.⚑
PMID 36323713 · Nat Commun · 2022
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spliceJAC: transition genes and state-specific gene regulation from single-cell transcriptome data.⚑
PMID 36321549 · Mol Syst Biol · 2022
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CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons.
PMID 36262316 · iScience · 2022
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Gene module regulation in dilated cardiomyopathy and the role of Na/K-ATPase.⚑
PMID 35901050 · PLoS One · 2022
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Systematic identification of ACE2 expression modulators reveals cardiomyopathy as a risk factor for mortality in COVID-19 patients.
PMID 35012625 · Genome Biol · 2022
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Preparation of mouse pancreatic tumor for single-cell RNA sequencing and analysis of the data.
PMID 34927097 · STAR Protoc · 2021
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Monocarboxylate Transporter-2 Expression Restricts Tumor Growth in a Murine Model of Lung Cancer: A Multi-Omic Analysis.⚑
PMID 34638954 · Int J Mol Sci · 2021
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A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells.
PMID 34426512 · Genome Res · 2021
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Creation of a Single Cell RNASeq Meta-Atlas to Define Human Liver Immune Homeostasis.⚑
PMID 34335581 · Front Immunol · 2021
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Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity.
PMID 33837217 · Nat Commun · 2021
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Estimating and Correcting for Off-Target Cellular Contamination in Brain Cell Type Specific RNA-Seq Data.
PMID 33746712 · Front Mol Neurosci · 2021
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Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression.
PMID 33722289 · Genome Biol · 2021
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Regulatory and evolutionary adaptation of yeast to acute lethal ethanol stress.
PMID 33170850 · PLoS One · 2020
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Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
PMID 33086062 · Cell Rep · 2020
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Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury.
PMID 33021470 · Elife · 2020
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Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells.⚑
PMID 32596448 · Sci Adv · 2020
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miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems.
PMID 32374865 · Nucleic Acids Res · 2020
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