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Reproducible, portable, and efficient ancient genome reconstruction with nf-core/eager.
PMID 33777521 · PeerJ · 2021
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Development of double-positive thymocytes at single-cell resolution.
PMID 33771202 · Genome Med · 2021
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The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.
PMID 33772001 · Nat Commun · 2021
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Topological signatures in regulatory network enable phenotypic heterogeneity in small cell lung cancer.
PMID 33729159 · Elife · 2021
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Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
PMID 33743211 · Cell · 2021
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Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility.
PMID 33707641 · Sci Rep · 2021
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The SARS-CoV-2 subgenome landscape and its novel regulatory features.
PMID 33713597 · Mol Cell · 2021
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Polyploidy-associated paramutation in Arabidopsis is determined by small RNAs, temperature, and allele structure.
PMID 33690630 · PLoS Genet · 2021
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TSUNAMI: Translational Bioinformatics Tool Suite for Network Analysis and Mining.
PMID 33705981 · Genomics Proteomics Bioinformatics · 2021
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Daily temperature cycles promote alternative splicing of RNAs encoding SR45a, a splicing regulator in maize.
PMID 33705553 · Plant Physiol · 2021
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CRISPRbuilder-TB: "CRISPR-builder for tuberculosis". Exhaustive reconstruction of the CRISPR locus in mycobacterium tuberculosis complex using SRA.
PMID 33667225 · PLoS Comput Biol · 2021
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Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
PMID 33674593 · Nat Commun · 2021
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A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport.
PMID 33649340 · Nat Commun · 2021
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In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.
PMID 33636127 · Cell · 2021
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Experimental identification and in silico prediction of bacterivory in green algae.
PMID 33649548 · ISME J · 2021
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Potentially bioavailable iron produced through benthic cycling in glaciated Arctic fjords of Svalbard.
PMID 33649339 · Nat Commun · 2021
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Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma.
PMID 33634984 · Clin Transl Med · 2021
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Curation of over 10 000 transcriptomic studies to enable data reuse.
PMID 33599246 · Database (Oxford) · 2021
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Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials.
PMID 33558569 · Sci Data · 2021
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IsomiR_Window: a system for analyzing small-RNA-seq data in an integrative and user-friendly manner.
PMID 33522913 · BMC Bioinformatics · 2021
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Expression quantitative trait loci in sheep liver and muscle contribute to variations in meat traits.
PMID 33461502 · Genet Sel Evol · 2021
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Current status of use of high throughput nucleotide sequencing in rheumatology.
PMID 33408124 · RMD Open · 2021
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Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis.
PMID 33253310 · PLoS Pathog · 2020
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aCLImatise: automated generation of tool definitions for bioinformatics workflows.
PMID 33325479 · Bioinformatics · 2021
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Macrel: antimicrobial peptide screening in genomes and metagenomes.
PMID 33384902 · PeerJ · 2020
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4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans.
PMID 33301041 · Nucleic Acids Res · 2020
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Systematic clustering algorithm for chromatin accessibility data and its application to hematopoietic cells.
PMID 33253153 · PLoS Comput Biol · 2020
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Fractional ridge regression: a fast, interpretable reparameterization of ridge regression.
PMID 33252656 · Gigascience · 2020
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GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline.
PMID 33193602 · Front Genet · 2020
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An informatics research platform to make public gene expression time-course datasets reusable for more scientific discoveries.
PMID 33247935 · Database (Oxford) · 2020
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PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy.
PMID 33188038 · J Immunother Cancer · 2020
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Genomic regions and signaling pathways associated with indicator traits for feed efficiency in juvenile Atlantic salmon (Salmo salar).
PMID 33158415 · Genet Sel Evol · 2020
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Functional module detection through integration of single-cell RNA sequencing data with protein-protein interaction networks.
PMID 33138772 · BMC Genomics · 2020
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Inference of Subpathway Activity Profiles Reveals Metabolism Abnormal Subpathway Regions in Glioblastoma Multiforme.
PMID 33072547 · Front Oncol · 2020
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Evaluating Distribution and Prognostic Value of New Tumor-Infiltrating Lymphocytes in HCC Based on a scRNA-Seq Study With CIBERSORTx.
PMID 33043022 · Front Med (Lausanne) · 2020
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The archives are half-empty: an assessment of the availability of microbial community sequencing data.
PMID 32859925 · Commun Biol · 2020
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In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.
PMID 32898168 · PLoS Biol · 2020
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Colorectal Cancer Prediction Based on Weighted Gene Co-Expression Network Analysis and Variational Auto-Encoder.⚑
PMID 32825264 · Biomolecules · 2020
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SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells.
PMID 32770939 · BMC Genomics · 2020
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Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins.
PMID 32773039 · Elife · 2020
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Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis.
PMID 32762840 · Elife · 2020
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A Meta-Analysis of Wolbachia Transcriptomics Reveals a Stage-Specific Wolbachia Transcriptional Response Shared Across Different Hosts.⚑
PMID 32718933 · G3 (Bethesda) · 2020
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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality.
PMID 32681306 · Curr Genet · 2020
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Meta-analysis of gene expression profiles of lean and obese PCOS to identify differentially regulated pathways and risk of comorbidities.
PMID 32695266 · Comput Struct Biotechnol J · 2020
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Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia.
PMID 32581241 · Nat Commun · 2020
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An Erg-driven transcriptional program controls B cell lymphopoiesis.
PMID 32541654 · Nat Commun · 2020
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Prediction of Antimicrobial Resistance in Gram-Negative Bacteria From Whole-Genome Sequencing Data.
PMID 32528441 · Front Microbiol · 2020
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Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs.
PMID 32515737 · Elife · 2020
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Integrated omics in Drosophila uncover a circadian kinome.
PMID 32483184 · Nat Commun · 2020
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