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Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs.
PMID 41932885 · Nat Commun · 2026
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stDyer-image improves clustering analysis of spatially resolved transcriptomics and proteomics with morphological images.
PMID 41692960 · Bioinformatics · 2026
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Smart spatial omics (S2-omics) optimizes region of interest selection to capture molecular heterogeneity in diverse tissues.
PMID 41298871 · Nat Cell Biol · 2025
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Identification of a PRDM1-regulated T cell network to regulate atherosclerotic plaque inflammation.
PMID 41039608 · Genome Med · 2025
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The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus data repository.
PMID 40926267 · Genome Biol · 2025
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Enhanced Generalizability of RNA Secondary Structure Prediction via Convolutional Block Attention Network and Ensemble Learning.
PMID 40871599 · Molecules · 2025
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Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity.
PMID 40846763 · Nat Genet · 2025
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Metabolic reprogramming and prognostic insights in molecular landscapes driven by glycolysis in ovarian cancer.
PMID 40707588 · Sci Rep · 2025
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Protocol for assessing regulatory elements in murine heart using an AAV9-based massively parallel reporter assay.
PMID 40252222 · STAR Protoc · 2025
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Deubiquitination enzyme USP35 negatively regulates MAVS signaling to inhibit anti-tumor immunity.
PMID 40016186 · Cell Death Dis · 2025
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Direct observations of cross-scale wave-particle energy transfer in space plasmas.
PMID 39919183 · Sci Adv · 2025
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Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits.
PMID 39901160 · Genome Biol · 2025
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Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer.
PMID 38974967 · iScience · 2024
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Analytical code sharing practices in biomedical research.
PMID 38983240 · PeerJ Comput Sci · 2024
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A cell atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA sequencing.
PMID 38839790 · Sci Data · 2024
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Decoding and reconstructing disease relations between dry eye and depression: a multimodal investigation comprising meta-analysis, genetic pathways and Mendelia
PMID 38548265 · J Adv Res · 2024
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5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia.
PMID 38277218 · Aging (Albany NY) · 2024
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Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma.
PMID 38230570 · Cancer Biol Ther · 2024
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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
PMID 38167725 · Nature Communications · 2024
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Exploring microproteins from various model organisms using the mip-mining database.
PMID 37919660 · BMC Genomics · 2023
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Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic l
PMID 37217248 · J Immunother Cancer · 2023
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Niche Modification by Sulfate-Reducing Bacteria Drives Microbial Community Assembly in Anoxic Marine Sediments.
PMID 36988509 · mBio · 2023
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Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer.
PMID 36851919 · Comput Struct Biotechnol J · 2023
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Transcriptome-wide analyses of piRNA binding sites suggest distinct mechanisms regulate piRNA binding and silencing in C. elegans.
PMID 36737102 · RNA · 2023
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Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance.
PMID 36543858 · Commun Biol · 2022
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Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs.
PMID 36414417 · · 2023
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COXPRESdb v8: an animal gene coexpression database navigating from a global view to detailed investigations.
PMID 36350658 · Nucleic Acids Res · 2023
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Functional differentiation determines the molecular basis of the symbiotic lifestyle of Ca. Nanohaloarchaeota.
PMID 36242054 · Microbiome · 2022
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The GATA factor ELT-3 specifies endoderm in Caenorhabditis angaria in an ancestral gene network.
PMID 36196618 · Development · 2022
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miR-4478 Accelerates Nucleus Pulposus Cells Apoptosis Induced by Oxidative Stress by Targeting MTH1.
PMID 36130054 · Spine (Phila Pa 1976) · 2022
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Assessment of genotyping array performance for genome-wide association studies and imputation in African cattle.
PMID 36057548 · Genet Sel Evol · 2022
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Identification and functional implications of pseudouridine RNA modification on small noncoding RNAs in the mammalian pathogen Trypanosoma brucei.
PMID 35714765 · J Biol Chem · 2022
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Transcriptomic-Based Quantification of the Epithelial-Hybrid-Mesenchymal Spectrum across Biological Contexts.
PMID 35053177 · Biomolecules · 2021
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The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation.
PMID 34938960 · FASEB Bioadv · 2021
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Lamin C is required to establish genome organization after mitosis.
PMID 34775987 · Genome Biol · 2021
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Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma.
PMID 34654806 · Nat Commun · 2021
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Reactivation of a developmentally silenced embryonic globin gene.
PMID 34290235 · Nat Commun · 2021
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Collisionless relaxation of a disequilibrated current sheet and implications for bifurcated structures.
PMID 34145266 · Nat Commun · 2021
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TGF-β-dependent reprogramming of amino acid metabolism induces epithelial-mesenchymal transition in non-small cell lung cancers.
PMID 34168290 · Commun Biol · 2021
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PredTAD: A machine learning framework that models 3D chromatin organization alterations leading to oncogene dysregulation in breast cancer cell lines.
PMID 34093998 · Comput Struct Biotechnol J · 2021
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Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
PMID 33674593 · Nat Commun · 2021
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Experimental identification and in silico prediction of bacterivory in green algae.
PMID 33649548 · ISME J · 2021
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Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis.
PMID 32762840 · Elife · 2020
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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality.
PMID 32681306 · Curr Genet · 2020
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Integrated omics in Drosophila uncover a circadian kinome.
PMID 32483184 · Nat Commun · 2020
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A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles.
PMID 32111252 · Genome Med · 2020
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Firefly genomes illuminate parallel origins of bioluminescence in beetles.
PMID 30324905 · Elife · 2018
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Metabolite-Centric Reporter Pathway and Tripartite Network Analysis of Arabidopsis Under Cold Stress.
PMID 30258841 · Front Bioeng Biotechnol · 2018
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Metavisitor, a Suite of Galaxy Tools for Simple and Rapid Detection and Discovery of Viruses in Deep Sequence Data.
PMID 28045932 · PLoS One · 2017
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