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A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre.
PMID 34140473 · Nat Commun · 2021
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R2DT is a framework for predicting and visualising RNA secondary structure using templates.
PMID 34108470 · Nat Commun · 2021
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Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathway
PMID 34095875 · Cell Rep Med · 2021
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PredTAD: A machine learning framework that models 3D chromatin organization alterations leading to oncogene dysregulation in breast cancer cell lines.
PMID 34093998 · Comput Struct Biotechnol J · 2021
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Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis.
PMID 34079055 · Commun Biol · 2021
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RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis.
PMID 34082707 · BMC Bioinformatics · 2021
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pyrpipe: a Python package for RNA-Seq workflows.
PMID 34085037 · NAR Genom Bioinform · 2021
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Duvernoy's Gland Transcriptomics of the Plains Black-Headed Snake, Tantilla nigriceps (Squamata, Colubridae): Unearthing the Venom of Small Rear-Fanged S
PMID 34066626 · Toxins (Basel) · 2021
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Similarities and Differences in Gene Expression Networks Between the Breast Cancer Cell Line Michigan Cancer Foundation-7 and Invasive Human Breast Cancer Tissu
PMID 34056582 · Front Artif Intell · 2021
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High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies.
PMID 34010620 · Cell · 2021
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Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
PMID 33999949 · PLoS Pathog · 2021
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Accelerated Evolution of Tissue-Specific Genes Mediates Divergence Amidst Gene Flow in European Green Lizards.⚑
PMID 33988711 · Genome Biol Evol · 2021
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Landscape of allele-specific transcription factor binding in the human genome.
PMID 33980847 · Nat Commun · 2021
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Genomics of Environmental Salmonella: Engaging Students in the Microbiology and Bioinformatics of Foodborne Pathogens.
PMID 33967968 · Front Microbiol · 2021
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From tides to nucleotides: Genomic signatures of adaptation to environmental heterogeneity in barnacles.
PMID 33960035 · Mol Ecol · 2021
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The Dockstore: enhancing a community platform for sharing reproducible and accessible computational protocols.
PMID 33978761 · Nucleic Acids Res · 2021
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Determination of complete chromosomal haplotypes by bulk DNA sequencing.
PMID 33957932 · Genome Biol · 2021
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geneshot: gene-level metagenomics identifies genome islands associated with immunotherapy response.
PMID 33952321 · Genome Biol · 2021
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Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.⚑
PMID 33948572 · Cell Rep Med · 2021
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Human methylome variation across Infinium 450K data on the Gene Expression Omnibus.
PMID 33937763 · NAR Genom Bioinform · 2021
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Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer.
PMID 33890574 · Elife · 2021
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76/100
SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses.
PMID 33932985 · BMC Bioinformatics · 2021
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Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses.
PMID 33871355 · Elife · 2021
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Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity.
PMID 33837217 · Nat Commun · 2021
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Analysis of whole-genome re-sequencing data of ducks reveals a diverse demographic history and extensive gene flow between Southeast/South Asian and Chinese pop⚑
PMID 33849442 · Genet Sel Evol · 2021
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23/100
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Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra.
PMID 33779545 · Elife · 2021
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Diapause vs. reproductive programs: transcriptional phenotypes in a keystone copepod.⚑
PMID 33782539 · Commun Biol · 2021
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The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.
PMID 33772001 · Nat Commun · 2021
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GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses.
PMID 33758032 · mSystems · 2021
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Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
PMID 33743211 · Cell · 2021
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Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility.
PMID 33707641 · Sci Rep · 2021
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Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy.
PMID 33723257 · Nat Commun · 2021
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Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression.
PMID 33722289 · Genome Biol · 2021
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TSUNAMI: Translational Bioinformatics Tool Suite for Network Analysis and Mining.
PMID 33705981 · Genomics Proteomics Bioinformatics · 2021
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Daily temperature cycles promote alternative splicing of RNAs encoding SR45a, a splicing regulator in maize.
PMID 33705553 · Plant Physiol · 2021
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Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
PMID 33674593 · Nat Commun · 2021
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Experimental identification and in silico prediction of bacterivory in green algae.
PMID 33649548 · ISME J · 2021
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Potentially bioavailable iron produced through benthic cycling in glaciated Arctic fjords of Svalbard.
PMID 33649339 · Nat Commun · 2021
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Extensive tissue-specific expression variation and novel regulators underlying circadian behavior.
PMID 33514540 · Sci Adv · 2021
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Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma.
PMID 33420019 · Nat Commun · 2021
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Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis.
PMID 33253310 · PLoS Pathog · 2020
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Prediction of Alzheimer's disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening.
PMID 33397809 · Proc Natl Acad Sci U S A · 2021
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Fractional ridge regression: a fast, interpretable reparameterization of ridge regression.
PMID 33252656 · Gigascience · 2020
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An informatics research platform to make public gene expression time-course datasets reusable for more scientific discoveries.
PMID 33247935 · Database (Oxford) · 2020
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PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy.
PMID 33188038 · J Immunother Cancer · 2020
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Regulatory and evolutionary adaptation of yeast to acute lethal ethanol stress.
PMID 33170850 · PLoS One · 2020
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Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
PMID 33086062 · Cell Rep · 2020
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Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury.
PMID 33021470 · Elife · 2020
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In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.
PMID 32898168 · PLoS Biol · 2020
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