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Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.
PMID 34561431 · Nat Commun · 2021
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HTSQualC is a flexible and one-step quality control software for high-throughput sequencing data analysis.
PMID 34548573 · Sci Rep · 2021
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Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design.
PMID 34553212 · Gigascience · 2021
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Frequency and patterns of ribonucleotide incorporation around autonomously replicating sequences in yeast reveal the division of labor of replicative DNA polyme
PMID 34551434 · Nucleic Acids Res · 2021
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A chromosome-scale genome assembly and karyotype of the ctenophore Hormiphora californensis.
PMID 34545398 · G3 (Bethesda) · 2021
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Comparative Genomics Provides Insight into the Function of Broad-Host Range Sponge Symbionts.
PMID 34519538 · mBio · 2021
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GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning.
PMID 34461978 · Genome Med · 2021
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CONSULT: accurate contamination removal using locality-sensitive hashing.
PMID 34377979 · NAR Genom Bioinform · 2021
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Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's diseas
PMID 34297416 · Neuropathol Appl Neurobiol · 2021
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Reactivation of a developmentally silenced embryonic globin gene.
PMID 34290235 · Nat Commun · 2021
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DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data.
PMID 34261540 · Genome Med · 2021
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Collisionless relaxation of a disequilibrated current sheet and implications for bifurcated structures.
PMID 34145266 · Nat Commun · 2021
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TGF-β-dependent reprogramming of amino acid metabolism induces epithelial-mesenchymal transition in non-small cell lung cancers.
PMID 34168290 · Commun Biol · 2021
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A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre.
PMID 34140473 · Nat Commun · 2021
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R2DT is a framework for predicting and visualising RNA secondary structure using templates.
PMID 34108470 · Nat Commun · 2021
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Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathway
PMID 34095875 · Cell Rep Med · 2021
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PredTAD: A machine learning framework that models 3D chromatin organization alterations leading to oncogene dysregulation in breast cancer cell lines.
PMID 34093998 · Comput Struct Biotechnol J · 2021
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Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis.
PMID 34079055 · Commun Biol · 2021
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RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis.
PMID 34082707 · BMC Bioinformatics · 2021
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pyrpipe: a Python package for RNA-Seq workflows.
PMID 34085037 · NAR Genom Bioinform · 2021
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Duvernoy's Gland Transcriptomics of the Plains Black-Headed Snake, Tantilla nigriceps (Squamata, Colubridae): Unearthing the Venom of Small Rear-Fanged S
PMID 34066626 · Toxins (Basel) · 2021
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Similarities and Differences in Gene Expression Networks Between the Breast Cancer Cell Line Michigan Cancer Foundation-7 and Invasive Human Breast Cancer Tissu
PMID 34056582 · Front Artif Intell · 2021
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High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies.
PMID 34010620 · Cell · 2021
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Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
PMID 33999949 · PLoS Pathog · 2021
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Landscape of allele-specific transcription factor binding in the human genome.
PMID 33980847 · Nat Commun · 2021
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Determination of complete chromosomal haplotypes by bulk DNA sequencing.
PMID 33957932 · Genome Biol · 2021
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geneshot: gene-level metagenomics identifies genome islands associated with immunotherapy response.
PMID 33952321 · Genome Biol · 2021
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Human methylome variation across Infinium 450K data on the Gene Expression Omnibus.
PMID 33937763 · NAR Genom Bioinform · 2021
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Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer.
PMID 33890574 · Elife · 2021
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Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses.
PMID 33871355 · Elife · 2021
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Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra.
PMID 33779545 · Elife · 2021
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The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.
PMID 33772001 · Nat Commun · 2021
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Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
PMID 33743211 · Cell · 2021
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Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility.
PMID 33707641 · Sci Rep · 2021
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TSUNAMI: Translational Bioinformatics Tool Suite for Network Analysis and Mining.
PMID 33705981 · Genomics Proteomics Bioinformatics · 2021
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Daily temperature cycles promote alternative splicing of RNAs encoding SR45a, a splicing regulator in maize.
PMID 33705553 · Plant Physiol · 2021
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Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
PMID 33674593 · Nat Commun · 2021
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Experimental identification and in silico prediction of bacterivory in green algae.
PMID 33649548 · ISME J · 2021
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Potentially bioavailable iron produced through benthic cycling in glaciated Arctic fjords of Svalbard.
PMID 33649339 · Nat Commun · 2021
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Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis.
PMID 33253310 · PLoS Pathog · 2020
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Fractional ridge regression: a fast, interpretable reparameterization of ridge regression.
PMID 33252656 · Gigascience · 2020
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An informatics research platform to make public gene expression time-course datasets reusable for more scientific discoveries.
PMID 33247935 · Database (Oxford) · 2020
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PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy.
PMID 33188038 · J Immunother Cancer · 2020
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In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.
PMID 32898168 · PLoS Biol · 2020
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SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells.
PMID 32770939 · BMC Genomics · 2020
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Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins.
PMID 32773039 · Elife · 2020
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Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis.
PMID 32762840 · Elife · 2020
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A Meta-Analysis of Wolbachia Transcriptomics Reveals a Stage-Specific Wolbachia Transcriptional Response Shared Across Different Hosts.⚑
PMID 32718933 · G3 (Bethesda) · 2020
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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality.
PMID 32681306 · Curr Genet · 2020
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