Marie C. Sadler

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.

How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.
  2021 L1 100/100

1 assessed by us (1 reproduced) · 53 not yet assessed — every PubMed paper on record, linked below.

• Integration of genetic evidence to identify approved drug targets ↗

  Genome Medicine · 2026 · PMID 42410617
  not yet assessed
• LiMA: Robust inference of molecular mediation from summary statistics ↗

  The American Journal of Human Genetics · 2026 · PMID 41512839
  not yet assessed
• Leveraging large-scale biobank EHRs to enhance pharmacogenetics of cardiometabolic disease medications ↗

  Nature Communications · 2025 · PMID 40133288
  not yet assessed
• Genetic association studies using disease liabilities from deep neural networks ↗

  The American Journal of Human Genetics · 2025 · PMID 39986278
  not yet assessed
• Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases ↗

  PLoS Genetics · 2025 · PMID 41325371
  not yet assessed
• Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases ↗

  2025
  not yet assessed
• Causality-enriched epigenetic age uncouples damage and adaptation ↗

  Nature Aging · 2024 · PMID 38243142
  not yet assessed
• Rare copy-number variants as modulators of common disease susceptibility ↗

  Genome Medicine · 2024 · PMID 38185688
  not yet assessed
• Breaking down causes, consequences, and mediating effects of telomere length variation on human health ↗

  Genome biology · 2024 · PMID 38760657
  not yet assessed
• Making genome editing a success story in Africa ↗

  Nature Biotechnology · 2024 · PMID 38504013
  not yet assessed
• Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks ↗

  Scientific Reports · 2024 · PMID 39632930
  not yet assessed
• Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples ↗

  BJPsych Open · 2024 · PMID 39635766
  not yet assessed
• Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort ↗

  Translational Psychiatry · 2024 · PMID 39548087
  not yet assessed
• Leveraging large-scale biobank EHRs to enhance pharmacogenetics of cardiometabolic disease medications ↗

  medRxiv · 2024 · PMID 38633781
  not yet assessed
• Breaking down causes, consequences, and mediating effects of age-related telomere shortening on human health ↗

  medRxiv · 2024
  not yet assessed
• Identifying DNA methylation sites affecting drug response using electronic health record–derived GWAS summary statistics ↗

  2024 · PMID 39670389
  not yet assessed
• Multi-layered genetic approaches to identify approved drug targets ↗

  Cell Genomics · 2023 · PMID 37492104
  not yet assessed
• Chromosomal deletions on 16p11.2 encompassing SH2B1 are associated with accelerated metabolic disease ↗

  Cell Reports Medicine · 2023 · PMID 37586323
  not yet assessed
• Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations ↗

  eLife · 2023 · PMID 36891970
  not yet assessed
• Promises and challenges in pharmacoepigenetics ↗

  Cambridge Prisms Precision Medicine · 2023 · PMID 37560024
  not yet assessed
• The impact of 22q11.2 copy-number variants on human traits in the general population ↗

  The American Journal of Human Genetics · 2023 · PMID 36706759
  not yet assessed
• Genetic association studies using disease liabilities from deep neural networks ↗

  medRxiv · 2023 · PMID 36712099
  not yet assessed
• Copy-number variants as modulators of common disease susceptibility ↗

  medRxiv · 2023
  not yet assessed
• Review: Promises and challenges in pharmacoepigenetics — R1/PR7 ↗

  2023
  not yet assessed
• Recommendation: Promises and challenges in pharmacoepigenetics — R1/PR8 ↗

  2023
  not yet assessed
• Decision: Promises and challenges in pharmacoepigenetics — R1/PR9 ↗

  2023
  not yet assessed
• Decision: Promises and challenges in pharmacoepigenetics — R0/PR5 ↗

  2023
  not yet assessed
• Multi-layered genetic approaches to identify approved drug targets ↗

  medRxiv · 2023
  not yet assessed
• Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts ↗

  npj Genomic Medicine · 2023 · PMID 37225732
  not yet assessed
• Response to Bassett et al. ↗

  The American Journal of Human Genetics · 2023 · PMID 37419093
  not yet assessed
• Reviewer #1 (Public Review): Novel discoveries and enhanced genomic prediction from modelling genetic risk of cancer age-at-onset ↗

  2023
  not yet assessed
• Novel discoveries and enhanced genomic prediction from modelling genetic risk of cancer age-at-onset ↗

  2023
  not yet assessed
• Novel discoveries and enhanced genomic prediction from modelling genetic risk of cancer age-at-onset ↗

  2023
  not yet assessed
• Gene prioritization scores and drug target information ↗

  Zenodo (CERN European Organization for Nuclear Research) · 2023
  not yet assessed
• Gene prioritization scores and drug target information ↗

  Zenodo (CERN European Organization for Nuclear Research) · 2023
  not yet assessed
• The individual and global impact of copy-number variants on complex human traits ↗

  The American Journal of Human Genetics · 2022 · PMID 35240056
  not yet assessed
• Sex- and age-dependent genetics of longevity in a heterogeneous mouse population ↗

  Science · 2022 · PMID 36173858
  not yet assessed
• From pharmacogenetics to pharmaco-omics: Milestones and future directions ↗

  Human Genetics and Genomics Advances · 2022 · PMID 35373152
  not yet assessed
• Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases ↗

  Nature Communications · 2022 · PMID 36477627
  not yet assessed
• Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts ↗

  npj Genomic Medicine · 2022 · PMID 35715439
  not yet assessed
• Causality-Enriched Epigenetic Age Uncouples Damage and Adaptation ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Novel discoveries and enhanced genomic prediction from modelling genetic risk of cancer age-at-onset ↗

  medRxiv · 2022
  not yet assessed
• Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• The impact of 22q11.2 copy number variants on human traits in the general population ↗

  medRxiv · 2022
  not yet assessed
• Recommendation: Promises and challenges in pharmacoepigenetics — R0/PR4 ↗

  2022
  not yet assessed
• Review: Promises and challenges in pharmacoepigenetics — R0/PR3 ↗

  2022
  not yet assessed
• Review: Promises and challenges in pharmacoepigenetics — R0/PR2 ↗

  2022
  not yet assessed
• Author response: Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations ↗

  2022
  not yet assessed
• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

  Nature Communications · 2021 · PMID 34561431
  L1 100/100
• Mendelian randomization to assess causality between uromodulin, blood pressure and chronic kidney disease ↗

  Kidney International · 2021 · PMID 34634361
  not yet assessed
• The individual and global impact of copy number variants on complex human traits ↗

  medRxiv · 2021
  not yet assessed
• Quantifying mediation between omics layers and complex traits ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2021
  not yet assessed
• Computational Surveillance of Microbial Water Quality With Online Flow Cytometry ↗

  Frontiers in Water · 2020
  not yet assessed
• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome ↗

  medRxiv · 2020
  not yet assessed