Brian D. Hobbs

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.

How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• Partial correlation network analysis identifies coordinated gene expression within a regional cluster of COPD genome-wide association signals.⚑
  2024 L1 23/100 ⚑

1 assessed by us (0 reproduced) · 236 not yet assessed — every PubMed paper on record, linked below.

• Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants ↗

  Genome biology · 2026 · PMID 41535900
  not yet assessed
• Body Mass Index-related genetic factors and COPD imaging phenotypes ↗

  Annals of the American Thoracic Society · 2026 · PMID 41721747
  not yet assessed
• Integrative multi-omic analyses identify major axes of heterogeneity in chronic obstructive pulmonary disease and uncover their molecular contributors ↗

  medRxiv · 2026 · PMID 41646689
  not yet assessed
• Publisher Correction: Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants ↗

  Genome biology · 2026 · PMID 42265570
  not yet assessed
• Publisher Correction: Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants. ↗

  UNC Libraries · 2026
  not yet assessed
• Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants ↗

  UNC Libraries · 2026
  not yet assessed
• Identification of smoking-enabled blood miRNA regulatory networks ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2026
  not yet assessed
• Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants ↗

  Science · 2025 · PMID 39913582
  not yet assessed
• Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk ↗

  Nature Genetics · 2025 · PMID 40050430
  not yet assessed
• Polygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease ↗

  JAMA · 2025 · PMID 39841442
  not yet assessed
• A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies ↗

  Nature Computational Science · 2025 · PMID 39920506
  not yet assessed
• Identifying chronic obstructive pulmonary disease subtypes using multi-trait genetics ↗

  EBioMedicine · 2025 · PMID 40010152
  not yet assessed
• Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele ↗

  Nature Communications · 2025 · PMID 40216759
  not yet assessed
• Genomic Ascertainment of <i>CHEK2</i> -Related Cancer Predisposition ↗

  JAMA Network Open · 2025 · PMID 41396600
  not yet assessed
• The Association of Interstitial Lung Abnormalities and Preserved Ratio Impaired Spirometry With Mortality ↗

  CHEST Journal · 2025 · PMID 39947315
  not yet assessed
• Peripheral blood miRNAs are associated with airflow below threshold in children with asthma ↗

  Respiratory Research · 2025 · PMID 39856653
  not yet assessed
• Assessing inflammatory protein biomarkers in COPD subjects with and without alpha-1 antitrypsin deficiency ↗

  Respiratory Research · 2025 · PMID 40665347
  not yet assessed
• Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts ↗

  medRxiv · 2025 · PMID 40502581
  not yet assessed
• miRNA-mRNA network analysis identifies PAX5 as a potential regulator of adaptive immune response in COPD ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 40654788
  not yet assessed
• Assessing Inflammatory Protein Biomarkers in COPD Subjects With and Without Alpha-1 Antitrypsin Deficiency ↗

  American Journal of Respiratory and Critical Care Medicine · 2025
  not yet assessed
• Deep Learning of Suboptimal Spirometry to Predict Respiratory Outcomes and Mortality ↗

  Research Square · 2025 · PMID 40630516
  not yet assessed
• Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals ↗

  Nature · 2025 · PMID 39779867
  not yet assessed
• Assessing Inflammatory Protein Biomarkers in COPD Subjects with and without Alpha-1 Antitrypsin Deficiency ↗

  medRxiv · 2025 · PMID 39867385
  not yet assessed
• Switch-like methylation of functional pathways distinguishes COPD and idiopathic pulmonary fibrosis ↗

  medRxiv · 2025 · PMID 41445629
  not yet assessed
• A deep catalogue of protein-coding variation in 983,578 individuals ↗

  Nature · 2024 · PMID 38768635
  not yet assessed
• Unsupervised representation learning on high-dimensional clinical data improves genomic discovery and prediction ↗

  Nature Genetics · 2024 · PMID 38977853
  not yet assessed
• Rare variant contribution to the heritability of coronary artery disease ↗

  Nature Communications · 2024 · PMID 39384761
  not yet assessed
• Chronic Obstructive Pulmonary Disease Exacerbations Increase the Risk of Subsequent Cardiovascular Events: A Longitudinal Analysis of the COPDGene Study ↗

  Journal of the American Heart Association · 2024 · PMID 38818936
  not yet assessed
• Sex-Biased Regulation of Extracellular Matrix Genes in Chronic Obstructive Pulmonary Disease ↗

  American Journal of Respiratory Cell and Molecular Biology · 2024 · PMID 39102858
  not yet assessed
• Genetically Predicted Body Mass Index and Mortality in Chronic Obstructive Pulmonary Disease ↗

  American Journal of Respiratory and Critical Care Medicine · 2024 · PMID 38471013
  not yet assessed
• Lung Transcriptomics Link Emphysema to Barrier Dysfunction and Macrophage Subpopulations ↗

  American Journal of Respiratory and Critical Care Medicine · 2024 · PMID 38935868
  not yet assessed
• Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies ↗

  EBioMedicine · 2024 · PMID 39509750
  not yet assessed
• Partial correlation network analysis identifies coordinated gene expression within a regional cluster of COPD genome-wide association signals⚑

  PLoS Computational Biology · 2024 · PMID 39418301
  L1 23/100 ⚑
• Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City ↗

  Nature · 2024 · PMID 38332034
  not yet assessed
• Clinical factors associated with racial differences in the prevalence of occult hypoxemia: a retrospective case-control study ↗

  medRxiv · 2024 · PMID 38585762
  not yet assessed
• Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries ↗

  Nature Genetics · 2024 · PMID 38641645
  not yet assessed
• Polygenic and Transcriptional Risk Scores Identify Chronic Obstructive Pulmonary Disease Subtypes ↗

  2024
  not yet assessed
• A Polygenic Risk Score and Case Finding for Chronic Obstructive Pulmonary Disease ↗

  2024
  not yet assessed
• The Predictive Utility of Omic Scores for COPD-related Traits ↗

  2024
  not yet assessed
• Whole-genome Sequencing Analyses of Imaging Phenotypes of Chronic Obstructive Pulmonary Disease ↗

  2024
  not yet assessed
• miRNA Network Modeling Identifies a Potential Role for PAX5 in COPD ↗

  2024
  not yet assessed
• Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes ↗

  medRxiv · 2024 · PMID 38826461
  not yet assessed
• Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function ↗

  Digital Commons@Becker (Washington University School of Medicine) · 2024
  not yet assessed
• Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program ↗

  UNC Libraries · 2024
  not yet assessed
• Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program ↗

  UNC Libraries · 2024
  not yet assessed
• BMI-related Genetic Factors and COPD Imaging Phenotypes ↗

  medRxiv · 2024
  not yet assessed
• A protein risk score for all-cause and respiratory-specific mortality in non-Hispanic white and African American individuals who smoke ↗

  Scientific Reports · 2024 · PMID 39232179
  not yet assessed
• Whole Genome Sequence Analysis of Pulmonary Function and COPD in 44,287 Multi-ancestry Participants ↗

  Research Square · 2024
  not yet assessed
• Clinical factors associated with racial differences in the prevalence of occult hypoxemia: a retrospective case-control study ↗

  2024
  not yet assessed
• Clonal haematopoiesis and risk of chronic liver disease ↗

  Nature · 2023 · PMID 37046084
  not yet assessed
• Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk ↗

  Nature Genetics · 2023 · PMID 36914875
  not yet assessed
• Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis ↗

  Nature · 2023 · PMID 37046083
  not yet assessed
• Genotyping, sequencing and analysis of 140,000 adults from Mexico City ↗

  Nature · 2023 · PMID 37821707
  not yet assessed
• Inference of chronic obstructive pulmonary disease with deep learning on raw spirograms identifies new genetic loci and improves risk models ↗

  Nature Genetics · 2023 · PMID 37069358
  not yet assessed
• A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities ↗

  American Journal of Respiratory and Critical Care Medicine · 2023 · PMID 37523715
  not yet assessed
• Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing ↗

  Nature Genetics · 2023 · PMID 36702996
  not yet assessed
• Augmentation Therapy for Severe Alpha-1 Antitrypsin Deficiency Improves Survival and Is Decoupled from Spirometric Decline—A Multinational Registry Analysis ↗

  American Journal of Respiratory and Critical Care Medicine · 2023 · PMID 37624745
  not yet assessed
• Deep learning on graphs for multi-omics classification of COPD ↗

  PLoS ONE · 2023 · PMID 37083575
  not yet assessed
• Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease ↗

  Journal of Allergy and Clinical Immunology · 2023 · PMID 37595761
  not yet assessed
• A large meta-analysis identifies genes associated with anterior uveitis ↗

  Nature Communications · 2023 · PMID 37949852
  not yet assessed
• Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma ↗

  EBioMedicine · 2023 · PMID 37598461
  not yet assessed
• Rare coding variants in CHRNB2 reduce the likelihood of smoking ↗

  Nature Genetics · 2023 · PMID 37308787
  not yet assessed
• Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function ↗

  American Journal of Respiratory and Critical Care Medicine · 2023 · PMID 37788444
  not yet assessed
• Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease ↗

  Respiratory Medicine · 2023 · PMID 36717002
  not yet assessed
• Identifying chronic obstructive pulmonary disease from integrative omics and clustering in lung tissue ↗

  BMC Pulmonary Medicine · 2023 · PMID 37041558
  not yet assessed
• X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study ↗

  Respiratory Research · 2023 · PMID 36726148
  not yet assessed
• Large scale proteomic studies create novel privacy considerations ↗

  Scientific Reports · 2023 · PMID 37286633
  not yet assessed
• Plasma metabolomics and quantitative interstitial abnormalities in ever-smokers ↗

  Respiratory Research · 2023 · PMID 37925418
  not yet assessed
• Variability in <i>MUC5B</i> Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis ↗

  American Journal of Respiratory and Critical Care Medicine · 2023 · PMID 36952240
  not yet assessed
• Deep Learning Utilizing Suboptimal Spirometry Data to Improve Lung Function and Mortality Prediction in the UK Biobank ↗

  medRxiv · 2023 · PMID 37162978
  not yet assessed
• Unsupervised representation learning improves genomic discovery and risk prediction for respiratory and circulatory functions and diseases ↗

  medRxiv · 2023 · PMID 37163049
  not yet assessed
• A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities ↗

  2023
  not yet assessed
• Identifying COPD subtypes using multi-trait genetics ↗

  medRxiv · 2023 · PMID 36865145
  not yet assessed
• WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE ↗

  medRxiv · 2023 · PMID 37662265
  not yet assessed
• Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk ↗

  Nature Genetics · 2023 · PMID 37749248
  not yet assessed
• Clinical Features of Genetic Resilience in Chronic Obstructive Pulmonary Disease ↗

  medRxiv · 2023 · PMID 36945553
  not yet assessed
• Divergent Lung Tissue Methylation Signatures of COPD and Pulmonary Fibrosis ↗

  2023
  not yet assessed
• Plasma Metabolomics and Quantitative Interstitial Abnormalities in Ever-smokers ↗

  2023
  not yet assessed
• Somatic mutations in chronic lung disease are associated with reduced lung function ↗

  medRxiv · 2023
  not yet assessed
• Genetic Risk for Body Mass and Mortality in COPD ↗

  2023
  not yet assessed
• Network Medicine Approaches Reveal Sex-biased Regulation of Extracellular Matrix Pathway in COPD ↗

  2023
  not yet assessed
• Clinical Features of Genetic Resilience in COPD ↗

  2023
  not yet assessed
• Augmentation therapy for severe alpha-1 antitrypsin deficiency improves survival but is decoupled from FEV1 decline ↗

  2023
  not yet assessed
• Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes ↗

  2023
  not yet assessed
• Additional file 2 of X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study ↗

  Open MIND · 2023
  not yet assessed
• Additional file 4 of X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study ↗

  Figshare · 2023
  not yet assessed
• Additional file 3 of X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study ↗

  Figshare · 2023
  not yet assessed
• Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data ↗

  Nature Genetics · 2022 · PMID 35256806
  not yet assessed
• Genetics of chronic obstructive pulmonary disease: understanding the pathobiology and heterogeneity of a complex disorder ↗

  The Lancet Respiratory Medicine · 2022 · PMID 35427534
  not yet assessed
• A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies ↗

  Nature Methods · 2022 · PMID 36303018
  not yet assessed
• Whole genome sequence analysis of blood lipid levels in &gt;66,000 individuals ↗

  Nature Communications · 2022 · PMID 36220816
  not yet assessed
• Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals ↗

  Nature Communications · 2022 · PMID 35995766
  not yet assessed
• Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies ↗

  Nature Genetics · 2022 · PMID 36564505
  not yet assessed
• The Proteomic Profile of Interstitial Lung Abnormalities ↗

  American Journal of Respiratory and Critical Care Medicine · 2022 · PMID 35438610
  not yet assessed
• Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease ↗

  EBioMedicine · 2022 · PMID 36155958
  not yet assessed
• A polygenic risk score and age of diagnosis of COPD ↗

  European Respiratory Journal · 2022 · PMID 35115341
  not yet assessed
• Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease

  UCL Discovery (University College London) · 2022
  not yet assessed
• Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis ↗

  Respiratory Research · 2022 · PMID 35449067
  not yet assessed
• Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies ↗

  Respiratory Research · 2022 · PMID 35715807
  not yet assessed
• Blood miRNAs Are Linked to Frequent Asthma Exacerbations in Childhood Asthma and Adult COPD ↗

  Non-Coding RNA · 2022 · PMID 35447890
  not yet assessed
• A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables ↗

  PLoS Genetics · 2022 · PMID 36383614
  not yet assessed
• Recent advancements in understanding the genetic involvement of alpha-1 antitrypsin deficiency associated lung disease: a look at future precision medicine approaches ↗

  Expert Review of Respiratory Medicine · 2022 · PMID 35025710
  not yet assessed
• Genetic Association Study Advances Idiopathic Pulmonary Fibrosis Pathophysiology and Health Equity ↗

  American Journal of Respiratory and Critical Care Medicine · 2022 · PMID 35504013
  not yet assessed
• Multi-ancestry genome-wide association study improves resolution of genes, pathways and pleiotropy for lung function and chronic obstructive pulmonary disease ↗

  medRxiv · 2022
  not yet assessed
• X Chromosome Associations with Chronic Obstructive Pulmonary Disease and Related Phenotypes: An X Chromosome-wide Association Study ↗

  Research Square · 2022
  not yet assessed
• Leveraging deep-learning on raw spirograms to improve genetic understanding and risk scoring of COPD despite noisy labels ↗

  medRxiv · 2022
  not yet assessed
• Novel privacy considerations for large scale proteomics ↗

  2022
  not yet assessed
• Blood Gene Expression Risk Profiles and Interstitial Lung Abnormalities: COPDGene and ECLIPSE cohort studies ↗

  medRxiv · 2022
  not yet assessed
• Novel Privacy Considerations for Large Scale Proteomics ↗

  medRxiv · 2022
  not yet assessed
• Lung Tissue Gene Expression Profile of Eosinophilic Chronic Obstructive Pulmonary Disease ↗

  2022
  not yet assessed
• The Association of Asthma and COPD Polygenic Risk Scores with Asthma-COPD Overlap and Related Outcomes ↗

  2022
  not yet assessed
• Identifying Chronic Obstructive Pulmonary Disease from Integrative Omics and Clustering in Lung Tissue ↗

  Research Square · 2022
  not yet assessed
• Lung transcriptomics of radiologic emphysema reveal barrier function impairment and macrophage M1-M2 imbalance ↗

  medRxiv · 2022
  not yet assessed
• Novel Privacy Considerations for Large Scale Proteomics ↗

  Research Square · 2022
  not yet assessed
• Additional file 2 of Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis ↗

  Open MIND · 2022
  not yet assessed
• Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program ↗

  Nature · 2021 · PMID 33568819
  not yet assessed
• A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response ↗

  Nature Genetics · 2021 · PMID 34611364
  not yet assessed
• Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors ↗

  BMC Pulmonary Medicine · 2021 · PMID 34261472
  not yet assessed
• Pulmonary Arterial Pruning and Longitudinal Change in Percent Emphysema and Lung Function ↗

  CHEST Journal · 2021 · PMID 33607083
  not yet assessed
• Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program ↗

  The American Journal of Human Genetics · 2021 · PMID 33887194
  not yet assessed
• Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease ↗

  American Journal of Respiratory and Critical Care Medicine · 2021 · PMID 34739356
  not yet assessed
• A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease ↗

  American Journal of Physiology-Lung Cellular and Molecular Physiology · 2021 · PMID 33909500
  not yet assessed
• Genome sequencing unveils a regulatory landscape of platelet reactivity ↗

  Nature Communications · 2021 · PMID 34131117
  not yet assessed
• Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers ↗

  CHEST Journal · 2021 · PMID 34785234
  not yet assessed
• Interaction of Cigarette Smoking and Polygenic Risk Score on Reduced Lung Function ↗

  JAMA Network Open · 2021 · PMID 34913977
  not yet assessed
• Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease ↗

  American Journal of Respiratory and Critical Care Medicine · 2021 · PMID 34762809
  not yet assessed
• Associations of Monocyte Count and Other Immune Cell Types with Interstitial Lung Abnormalities ↗

  American Journal of Respiratory and Critical Care Medicine · 2021 · PMID 34929108
  not yet assessed
• Heterozygosity of the Alpha 1‐Antitrypsin Pi*Z Allele and Risk of Liver Disease ↗

  Hepatology Communications · 2021 · PMID 34430780
  not yet assessed
• Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program ↗

  The American Journal of Human Genetics · 2021 · PMID 34582791
  not yet assessed
• Identifying miRNA-mRNA Networks Associated With COPD Phenotypes ↗

  Frontiers in Genetics · 2021 · PMID 34777474
  not yet assessed
• The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers ↗

  CHEST Journal · 2021 · PMID 33971144
  not yet assessed
• Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort ↗

  CHEST Journal · 2021 · PMID 34029566
  not yet assessed
• Variant-specific inflation factors for assessing population stratification at the phenotypic variance level ↗

  Nature Communications · 2021 · PMID 34108454
  not yet assessed
• Genetic Variation in the Mitochondrial Glycerol‐3‐Phosphate Acyltransferase Is Associated With Liver Injury ↗

  Hepatology · 2021 · PMID 34216018
  not yet assessed
• Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative ↗

  Human Molecular Genetics · 2021 · PMID 34553764
  not yet assessed
• Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease ↗

  Journal of Cachexia Sarcopenia and Muscle · 2021 · PMID 34523824
  not yet assessed
• Relationship Between Rheumatoid Arthritis and Pulmonary Function Measures on Spirometry in the UK Biobank ↗

  Arthritis & Rheumatology · 2021 · PMID 33982900
  not yet assessed
• Commercially Available Blocking Oligonucleotides Effectively Suppress Unwanted Hemolysis-Related miRNAs in a Large Whole-Blood RNA Cohort ↗

  Journal of Molecular Diagnostics · 2021 · PMID 33872788
  not yet assessed
• Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease ↗

  PLoS Genetics · 2021 · PMID 34784346
  not yet assessed
• Intermediate versus standard dose heparin prophylaxis in COVID-19 ICU patients: A propensity score-matched analysis ↗

  Thrombosis Research · 2021 · PMID 33940309
  not yet assessed
• Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program ↗

  The American Journal of Human Genetics · 2021
  not yet assessed
• A genome-wide association study of quantitative computed tomographic emphysema in Korean populations ↗

  Scientific Reports · 2021 · PMID 34404834
  not yet assessed
• Smoking Interaction with a Polygenic Risk Score for Reduced Lung Function ↗

  medRxiv · 2021
  not yet assessed
• Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response ↗

  Nature Genetics · 2021 · PMID 34728834
  not yet assessed
• Development of a Blood-Based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease ↗

  2021
  not yet assessed
• Metabo-Endotypes of Asthma Reveal Clinically Important Differences in Lung Function: Discovery and validation in two TOPMed Cohorts ↗

  Research Square · 2021
  not yet assessed
• A Polygenic Risk Score and Underdiagnosis of Chronic Obstructive Pulmonary Disease ↗

  2021
  not yet assessed
• Lung Tissue and Blood Co-Methylation Networks Reveal Local and Systemic Signatures of IPF and COPD with Similar and Divergent Effects ↗

  2021
  not yet assessed
• A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2021
  not yet assessed
• Metabo-Endotypes of Asthma Reveal Clinically Important Differences in Lung Function ↗

  2021
  not yet assessed
• Lung and Blood DNA Methylation in COPD and IPF Reveal Transcription Factor Perturbations ↗

  2021
  not yet assessed
• Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts ↗

  American Journal of Respiratory and Critical Care Medicine · 2021 · PMID 34767496
  not yet assessed
• Inherited causes of clonal haematopoiesis in 97,691 whole genomes ↗

  Nature · 2020 · PMID 33057201
  not yet assessed
• Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale ↗

  Nature Genetics · 2020 · PMID 32839606
  not yet assessed
• Machine Learning and Prediction of All-Cause Mortality in COPD ↗

  CHEST Journal · 2020 · PMID 32353417
  not yet assessed
• Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts ↗

  The Lancet Respiratory Medicine · 2020 · PMID 32649918
  not yet assessed
• De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population ↗

  Proceedings of the National Academy of Sciences · 2020 · PMID 31964835
  not yet assessed
• A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19 ↗

  EBioMedicine · 2020 · PMID 33039714
  not yet assessed
• Genome-Wide Gene-by-Smoking Interaction Study of Chronic Obstructive Pulmonary Disease ↗

  American Journal of Epidemiology · 2020 · PMID 33106845
  not yet assessed
• Clarifying the Risk of Lung Disease in SZ Alpha-1 Antitrypsin Deficiency ↗

  American Journal of Respiratory and Critical Care Medicine · 2020 · PMID 32197047
  not yet assessed
• Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules ↗

  Network and Systems Medicine · 2020 · PMID 33987620
  not yet assessed
• Consequences of Abrupt Cessation of Alpha ₁ -Antitrypsin Replacement Therapy ↗

  New England Journal of Medicine · 2020 · PMID 32268034
  not yet assessed
• Relative contributions of family history and a polygenic risk score on COPD and related outcomes: COPDGene and ECLIPSE studies ↗

  BMJ Open Respiratory Research · 2020 · PMID 33239407
  not yet assessed
• Trait Insights Gained by Comparing Genome-Wide Association Study Results using Different Chronic Obstructive Pulmonary Disease Definitions. ↗

  PubMed · 2020 · PMID 32477647
  not yet assessed
• Why is Disease Penetration So Variable? Role of Genetic Modifiers of Lung Function in Alpha-1 Antitrypsin Deficiency ↗

  Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation · 2020 · PMID 32621460
  not yet assessed
• Comorbidity-Based Clusters Contain Chaos in COPD ↗

  CHEST Journal · 2020 · PMID 32654700
  not yet assessed
• Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program ↗

  medRxiv · 2020
  not yet assessed
• Relative Contributions of Family History and a Polygenic Risk Score on COPD and Related Outcomes: COPDGene and ECLIPSE studies ↗

  medRxiv · 2020
  not yet assessed
• Corrigendum to ‘A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19’ ↗

  EBioMedicine · 2020 · PMID 33181463
  not yet assessed
• Connecting Past with Future - Circulating Micrornas Can Mediate Asthma Exacerbations in the Childhood Asthma Management Program (CAMP) ↗

  2020
  not yet assessed
• Genome-Wide Association Study of Asthma-COPD Overlap (ACO) Among UK Biobank Participants Provides Insights into Its Genetic Risk Factors ↗

  2020
  not yet assessed
• Risk Factors for Polycythemia and Increased Hematocrit in Smokers with and Without Chronic Obstructive Pulmonary Disease ↗

  2020
  not yet assessed
• Polygenic Risk Scores in Chronic Obstructive Pulmonary Disease and Related Phenotypes ↗

  2020
  not yet assessed
• Genome-Wide Discovery of Modifiers of Lung Function in Severe Alpha-1 Antitrypsin Deficiency ↗

  2020
  not yet assessed
• Integrating Genetics and Omics to Understand Chronic Obstructive Pulmonary Disease ↗

  Barcelona Respiratory Network · 2020
  not yet assessed
• Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis ↗

  UNC Libraries · 2020
  not yet assessed
• New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries ↗

  Nature Genetics · 2019 · PMID 30804560
  not yet assessed
• Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations ↗

  Nature Genetics · 2019 · PMID 30804561
  not yet assessed
• Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis ↗

  American Journal of Respiratory and Critical Care Medicine · 2019 · PMID 31710517
  not yet assessed
• COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease ↗

  Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation · 2019 · PMID 31710793
  not yet assessed
• Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis ↗

  Respiratory Research · 2019 · PMID 30940143
  not yet assessed
• Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis ↗

  American Journal of Respiratory and Critical Care Medicine · 2019 · PMID 31339356
  not yet assessed
• Subtyping COPD by Using Visual and Quantitative CT Imaging Features ↗

  CHEST Journal · 2019 · PMID 31283919
  not yet assessed
• Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene ↗

  American Journal of Respiratory and Critical Care Medicine · 2019 · PMID 30908940
  not yet assessed
• Machine Learning Characterization of COPD Subtypes ↗

  CHEST Journal · 2019 · PMID 31887283
  not yet assessed
• The St. George’s Respiratory Questionnaire Definition of Chronic Bronchitis May Be a Better Predictor of COPD Exacerbations Compared With the Classic Definition ↗

  CHEST Journal · 2019 · PMID 31047955
  not yet assessed
• Unsupervised discovery of phenotype-specific multi-omics networks ↗

  Bioinformatics · 2019 · PMID 30957844
  not yet assessed
• MicroRNAs in COPD: small molecules with big potential ↗

  European Respiratory Journal · 2019 · PMID 31023868
  not yet assessed
• Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene ↗

  PLoS Genetics · 2019 · PMID 31269066
  not yet assessed
• Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene ↗

  European Respiratory Journal · 2019 · PMID 31772001
  not yet assessed
• Exploring the cross-phenotype network region of disease modules reveals concordant and discordant pathways between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis ↗

  Human Molecular Genetics · 2019 · PMID 30997486
  not yet assessed
• Assessing pleiotropy and mediation in genetic loci associated with chronic obstructive pulmonary disease ↗

  Genetic Epidemiology · 2019 · PMID 30740764
  not yet assessed
• Genetics and epidemiology of AATD ↗

  European Respiratory Society eBooks · 2019
  not yet assessed
• Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations ↗

  Zurich Open Repository and Archive (University of Zurich) · 2019
  not yet assessed
• Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries ↗

  Nature Genetics · 2019 · PMID 31110354
  not yet assessed
• Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• Improved COPD Mortality Prediction Using Machine Learning in the COPDGene and ECLIPSE Studies ↗

  2019
  not yet assessed
• Genetic Overlap of Chronic Obstructive Pulmonary Disease and Cardiovascular Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis ↗

  2019
  not yet assessed
• Integrative Omics to Discover Novel Subtypes in a Chronic Obstructive Pulmonary Disease Lung Tissue Cohort ↗

  2019
  not yet assessed
• Genome-Wide Association Study of Parametric Response Mapping in the COPDGene Study Dissects Genetic Contributions to Emphysema and Functional Small Airway Disease ↗

  2019
  not yet assessed
• Exploring the Shared Molecular Networks of COPD and Idiopathic Pulmonary Fibrosis Reveals Concordant and Discordant Pathways in the Interactome ↗

  2019
  not yet assessed
• New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. ↗

  INDIGO (University of Illinois at Chicago) · 2019
  not yet assessed
• Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease ↗

  Journal of Allergy and Clinical Immunology · 2018 · PMID 29709670
  not yet assessed
• Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function ↗

  Nature Communications · 2018 · PMID 30061609
  not yet assessed
• Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations ↗

  Human Molecular Genetics · 2018 · PMID 29547942
  not yet assessed
• Whole exome sequencing analysis in severe chronic obstructive pulmonary disease ↗

  Human Molecular Genetics · 2018 · PMID 30060175
  not yet assessed
• Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls ↗

  Nicotine & Tobacco Research · 2018 · PMID 29767774
  not yet assessed
• A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants ↗

  Frontiers in Genetics · 2018 · PMID 29725345
  not yet assessed
• Genetic variants predicting aerobic capacity response to training are also associated with skeletal muscle oxidative capacity in moderate-to-severe COPD ↗

  Physiological Genomics · 2018 · PMID 29799805
  not yet assessed
• Crowdclustering with Partition Labels

  International Conference on Artificial Intelligence and Statistics · 2018
  not yet assessed
• Dissecting respiratory disease heterogeneity through the genetics of diffusing capacity ↗

  European Respiratory Journal · 2018 · PMID 30219754
  not yet assessed
• New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• A weighted genetic risk score based on 279 signals of association with lung function predicts Chronic Obstructive Pulmonary Disease ↗

  Genes and Environment · 2018
  not yet assessed
• Expanded genetic landscape of chronic obstructive pulmonary disease reveals heterogeneous cell type and phenotype associations ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• A Genome-Wide Association Study of > 250,000 Subjects Identifies Novel Risk Loci for COPD

  American Journal of Respiratory and Critical Care Medicine · 2018
  not yet assessed
• Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis ↗

  Nature Genetics · 2017 · PMID 28166215
  not yet assessed
• Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets ↗

  Nature Genetics · 2017 · PMID 28166213
  not yet assessed
• Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects ↗

  American Journal of Respiratory Cell and Molecular Biology · 2017 · PMID 28170284
  not yet assessed
• Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation ↗

  European Respiratory Journal · 2017 · PMID 29191953
  not yet assessed
• Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression ↗

  CHEST Journal · 2017 · PMID 28943279
  not yet assessed
• Gene‐based segregation method for identifying rare variants in family‐based sequencing studies ↗

  Genetic Epidemiology · 2017 · PMID 28191685
  not yet assessed
• Asthma Is a Risk Factor for Respiratory Exacerbations Without Increased Rate of Lung Function Decline ↗

  CHEST Journal · 2017 · PMID 29248621
  not yet assessed
• Multiethnic meta-analysis identifies new loci for pulmonary function ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Genetic variants predicting the response to endurance exercise training are also associated with skeletal muscle oxidative capacity in COPD ↗

  2017
  not yet assessed
• Whole Exome Sequencing Analysis Of Severe COPD

  Data Archiving and Networked Services (DANS) · 2017
  not yet assessed
• Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Exome Array Analysis Identifies a Common Variant in <i>IL27</i> Associated with Chronic Obstructive Pulmonary Disease ↗

  American Journal of Respiratory and Critical Care Medicine · 2016 · PMID 26771213
  not yet assessed
• Interpretable Clustering via Discriminative Rectangle Mixture Model ↗

  2016
  not yet assessed
• A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes ↗

  American Journal of Respiratory and Critical Care Medicine · 2015 · PMID 26030696
  not yet assessed
• Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study ↗

  Respiratory Research · 2015 · PMID 26392057
  not yet assessed
• A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease ↗

  The Pharmacogenomics Journal · 2015 · PMID 26503814
  not yet assessed
• Exome Array Analysis of Chronic Obstructive Pulmonary Disease

  Digital Access to Scholarship at Harvard (DASH) (Harvard University) · 2015
  not yet assessed
• Additional file 1: Table S1. of Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study ↗

  INDIGO (University of Illinois at Chicago) · 2015
  not yet assessed
• Pneumothorax Risk Factors in Smokers with and without Chronic Obstructive Pulmonary Disease ↗

  Annals of the American Thoracic Society · 2014 · PMID 25295410
  not yet assessed
• Integrative genomics of chronic obstructive pulmonary disease ↗

  Biochemical and Biophysical Research Communications · 2014 · PMID 25078622
  not yet assessed
• Incidentally Detected Lung Nodules ↗

  Journal of Computer Assisted Tomography · 2014 · PMID 24424558
  not yet assessed