Timothy M. Frayling

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

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How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.
  2021 L1 100/100

1 assessed by us (1 reproduced) · 666 not yet assessed — every PubMed paper on record, linked below.

• Genetic and epidemiological evidence linking respiratory and musculoskeletal diseases: shared risk factors and intervention windows ↗

  Respiratory Research · 2026 · PMID 42260503
  not yet assessed
• Polygenic prediction of body mass index and obesity through the life course and across ancestries ↗

  Nature Medicine · 2025 · PMID 40691366
  not yet assessed
• Whole-genome sequencing analysis identifies rare, large-effect noncoding variants and regulatory regions associated with circulating protein levels ↗

  Nature Genetics · 2025 · PMID 39994471
  not yet assessed
• Clinical utility of self-reported sleep duration and insomnia symptoms in type 2 diabetes prediction ↗

  Diabetologia · 2025 · PMID 40753283
  not yet assessed
• Weight Management in a Patient With Smith-Magenis Syndrome: The Role of GLP-1 Receptor Agonists ↗

  JCEM Case Reports · 2025 · PMID 40443456
  not yet assessed
• Effects of childhood and adult height on later life cardiovascular disease risk estimated through Mendelian randomization ↗

  European Journal of Epidemiology · 2025 · PMID 40106116
  not yet assessed
• Whole-genome sequencing analysis of anthropometric traits in 672,976 individuals reveals convergence between rare and common genetic associations ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• Genome-wide association studies identify shared mechanisms between hypertension and type 2 diabetes independent of adiposity ↗

  medRxiv · 2025
  not yet assessed
• Genotype-level quality control substantially reduces error rates in population-scale whole-genome sequencing ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• Subclassification of obesity for precision prediction of cardiometabolic diseases ↗

  Nature Medicine · 2024 · PMID 39448862
  not yet assessed
• Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height ↗

  Nature Communications · 2024 · PMID 39362880
  not yet assessed
• Hyperglycaemia is a causal risk factor for upper limb pathologies ↗

  International Journal of Epidemiology · 2024 · PMID 38205890
  not yet assessed
• Blood‐based multivariate methylation risk score for cognitive impairment and dementia ↗

  Alzheimer s & Dementia · 2024 · PMID 39193899
  not yet assessed
• Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor ↗

  Genetic Epidemiology · 2024 · PMID 39138631
  not yet assessed
• SMIM1 absence is associated with reduced energy expenditure and excess weight ↗

  Med · 2024 · PMID 38906141
  not yet assessed
• A Federated Database for Obesity Research: An IMI-SOPHIA Study ↗

  Life · 2024 · PMID 38398771
  not yet assessed
• The power of genetic diversity in genome-wide association studies of lipids ↗

  UNC Libraries · 2024
  not yet assessed
• A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data ↗

  medRxiv · 2024
  not yet assessed
• Author Correction: Subclassification of obesity for precision prediction of cardiometabolic diseases ↗

  Nature Medicine · 2024 · PMID 39572748
  not yet assessed
• Subclassification of obesity for precision prediction of cardiometabolic diseases: an IMI SOPHIA study ↗

  Research Square · 2024
  not yet assessed
• 277-OR: Whole-Genome Sequencing Identifies a Rare Noncoding Variant Proximal to METRN Associated with HbA1c Levels ↗

  Diabetes · 2024
  not yet assessed
• Author Correction: The power of genetic diversity in genome-wide association studies of lipids ↗

  RePEc: Research Papers in Economics · 2024
  not yet assessed
• The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits ↗

  Cell Metabolism · 2023 · PMID 36963395
  not yet assessed
• Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake ↗

  Nature Genetics · 2023 · PMID 37291194
  not yet assessed
• OTTERS: a powerful TWAS framework leveraging summary-level reference data ↗

  Nature Communications · 2023 · PMID 36882394
  not yet assessed
• Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review ↗

  European Journal of Epidemiology · 2023 · PMID 37938447
  not yet assessed
• Loci for insulin processing and secretion provide insight into type 2 diabetes risk ↗

  The American Journal of Human Genetics · 2023 · PMID 36693378
  not yet assessed
• Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood ↗

  Diabetologia · 2023 · PMID 37280435
  not yet assessed
• Genetic variants associated with weight loss and metabolic outcomes after bariatric surgery: A systematic review ↗

  Obesity Reviews · 2023 · PMID 37632325
  not yet assessed
• Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study ↗

  European Journal of Epidemiology · 2023 · PMID 37133737
  not yet assessed
• Identification and analysis of individuals who deviate from their genetically-predicted phenotype ↗

  PLoS Genetics · 2023 · PMID 37733769
  not yet assessed
• Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records ↗

  BMC Medical Genomics · 2023 · PMID 37784116
  not yet assessed
• Genetic predisposition to metabolically unfavourable adiposity and prostate cancer risk: A Mendelian randomization analysis ↗

  Cancer Medicine · 2023 · PMID 37305903
  not yet assessed
• Mediation and moderation of genetic risk of obesity through eating behaviours in two UK cohorts ↗

  International Journal of Epidemiology · 2023 · PMID 37410385
  not yet assessed
• Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications ↗

  medRxiv · 2023 · PMID 37034649
  not yet assessed
• Author Correction: The power of genetic diversity in genome-wide association studies of lipids ↗

  Nature · 2023 · PMID 37237109
  not yet assessed
• Whole genome association testing in 333,100 individuals across three biobanks identifies rare non-coding single variant and genomic aggregate associations with height ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2023
  not yet assessed
• A systematic literature review of methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology ↗

  medRxiv · 2023
  not yet assessed
• Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity ↗

  medRxiv · 2023
  not yet assessed
• Blood-based multivariate methylation risk score for cognitive impairment and dementia ↗

  medRxiv · 2023
  not yet assessed
• Whole genome sequencing analysis identifies rare, large-effect non-coding variants and regions associated with circulating protein levels ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2023
  not yet assessed
• Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion ↗

  medRxiv · 2023 · PMID 36798216
  not yet assessed
• Identification and analysis of individuals who deviate from their genetically-predicted phenotype ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 36798175
  not yet assessed
• Effects of childhood and adult height on later life cardiovascular disease risk estimated through Mendelian randomization ↗

  medRxiv · 2023
  not yet assessed
• Genetic susceptibility to obesity is partly mediated by emotional overeating during adolescence ↗

  Appetite · 2023
  not yet assessed
• Additional file 28 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 21 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 25 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 18 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 27 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 10 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 29 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 19 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (UWA) · 2023
  not yet assessed
• Additional file 4 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 17 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 2 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 33 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 32 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 5 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 30 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 7 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 8 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 20 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 22 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Discovery Research Portal (University of Dundee) · 2023
  not yet assessed
• Additional file 23 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 1 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Additional file 12 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  UWA Profiles and Research Repository (University of Western Australia) · 2023
  not yet assessed
• Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis ↗

  JNCI Journal of the National Cancer Institute · 2022 · PMID 35048991
  not yet assessed
• Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis ↗

  BMC Medicine · 2022 · PMID 35436960
  not yet assessed
• Rare genetic variants in genes and loci linked to dominant monogenic developmental disorders cause milder related phenotypes in the general population ↗

  The American Journal of Human Genetics · 2022 · PMID 35700724
  not yet assessed
• A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids ↗

  The American Journal of Human Genetics · 2022 · PMID 35931049
  not yet assessed
• Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  Genome biology · 2022 · PMID 36575460
  not yet assessed
• Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study ↗

  Diabetes Care · 2022 · PMID 35349659
  not yet assessed
• Detection and characterization of male sex chromosome abnormalities in the UK Biobank study ↗

  Genetics in Medicine · 2022 · PMID 35687092
  not yet assessed
• Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study ↗

  PLoS Genetics · 2022 · PMID 35061662
  not yet assessed
• <i>PLIN1</i> Haploinsufficiency Causes a Favorable Metabolic Profile ↗

  The Journal of Clinical Endocrinology & Metabolism · 2022 · PMID 35235652
  not yet assessed
• Understanding the complex genetic architecture connecting rheumatoid arthritis, osteoporosis and inflammation: discovering causal pathways ↗

  Human Molecular Genetics · 2022 · PMID 35349660
  not yet assessed
• Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns ↗

  Diabetes · 2022 · PMID 35061033
  not yet assessed
• Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies ↗

  The American Journal of Human Genetics · 2022 · PMID 36055212
  not yet assessed
• Genomics and multimorbidity ↗

  Age and Ageing · 2022 · PMID 36469092
  not yet assessed
• The impact of Mendelian sleep and circadian genetic variants in a population setting ↗

  PLoS Genetics · 2022 · PMID 36137075
  not yet assessed
• Simulated distributions from negative experiments highlight the importance of the body mass index distribution in explaining depression–body mass index genetic risk score interactions ↗

  International Journal of Epidemiology · 2022 · PMID 35388897
  not yet assessed
• 130  Does visual imagery vividness have a genetic basis? A genome-wide associa- tion study of 1019 individuals ↗

  Journal of Neurology Neurosurgery & Psychiatry · 2022
  not yet assessed
• A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Correction: Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation ↗

  eLife · 2022 · PMID 35583923
  not yet assessed
• The impact of Mendelian sleep and circadian genetic variants in a population setting ↗

  medRxiv · 2022
  not yet assessed
• Corrigendum to: A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin–creatinine ratio ↗

  Human Molecular Genetics · 2022 · PMID 35246685
  not yet assessed
• Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study ↗

  2022
  not yet assessed
• The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study ↗

  medRxiv · 2022
  not yet assessed
• Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns ↗

  2022
  not yet assessed
• Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns ↗

  2022
  not yet assessed
• Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study ↗

  2022
  not yet assessed
• Genomic insights into the mechanism of NK3R antagonists for treatment of menopausal vasomotor symptoms ↗

  medRxiv · 2022
  not yet assessed
• Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk ↗

  Human Molecular Genetics · 2022 · PMID 36048866
  not yet assessed
• Decision letter: Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis ↗

  2022
  not yet assessed
• Additional file 2 of Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis ↗

  Open MIND · 2022
  not yet assessed
• Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression ↗

  Nature Genetics · 2021 · PMID 34475573
  not yet assessed
• The power of genetic diversity in genome-wide association studies of lipids ↗

  Nature · 2021 · PMID 34887591
  not yet assessed
• The trans-ancestral genomic architecture of glycemic traits ↗

  Nature Genetics · 2021 · PMID 34059833
  not yet assessed
• Genetic insights into biological mechanisms governing human ovarian ageing ↗

  Nature · 2021 · PMID 34349265
  not yet assessed
• Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ↗

  Nature Communications · 2021 · PMID 33402679
  not yet assessed
• Genetic predictors of participation in optional components of UK Biobank ↗

  Nature Communications · 2021 · PMID 33563987
  not yet assessed
• Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour ↗

  Nature Human Behaviour · 2021 · PMID 34211149
  not yet assessed
• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

  Nature Communications · 2021 · PMID 34561431
  L1 100/100
• Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease ↗

  Diabetes · 2021 · PMID 33980691
  not yet assessed
• Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives ↗

  The Lancet Healthy Longevity · 2021 · PMID 34729547
  not yet assessed
• Higher adiposity and mental health: causal inference using Mendelian randomization ↗

  Human Molecular Genetics · 2021 · PMID 34270736
  not yet assessed
• A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor ↗

  PLoS Genetics · 2021 · PMID 34111113
  not yet assessed
• Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation ↗

  eLife · 2021 · PMID 35074047
  not yet assessed
• Mendelian Randomization Analyses Suggest Childhood Body Size Indirectly Influences End Points From Across the Cardiovascular Disease Spectrum Through Adult Body Size ↗

  Journal of the American Heart Association · 2021 · PMID 34465205
  not yet assessed
• Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile ↗

  Diabetologia · 2021 · PMID 34542646
  not yet assessed
• Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R ↗

  Cell · 2021 · PMID 33798434
  not yet assessed
• Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight ↗

  Human Molecular Genetics · 2021 · PMID 34897462
  not yet assessed
• Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile ↗

  Diabetic Medicine · 2021 · PMID 33501652
  not yet assessed
• 188-LB: Type 2 Diabetes Is Genetically Correlated with Multiple Long-Term Conditions but These Correlations Are Only Partly Explained by BMI ↗

  Diabetes · 2021
  not yet assessed
• Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

  Figshare · 2021
  not yet assessed
• Genetic insights into the biological mechanisms governing human ovarian ageing ↗

  medRxiv · 2021
  not yet assessed
• Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ↗

  medRxiv · 2021
  not yet assessed
• Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ↗

  Nature Communications · 2021 · PMID 33558525
  not yet assessed
• Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study ↗

  medRxiv · 2021
  not yet assessed
• A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2021
  not yet assessed
• Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis ↗

  medRxiv · 2021
  not yet assessed
• Age-specific effects of body size on fracture risk in later life: A lifecourse Mendelian randomization study ↗

  medRxiv · 2021
  not yet assessed
• Genetic Evidence for Different Adiposity Phenotypes and their Opposing Influence on Ectopic Fat and Risk of Cardiometabolic Disease ↗

  2021
  not yet assessed
• Associations of genetic scores for birth weight with newborn size and later anthropometric traits and cardiometabolic risk markers in South Asians ↗

  Research Square · 2021
  not yet assessed
• Rare genetic variants in dominant developmental disorder loci cause milder related phenotypes in the general population ↗

  medRxiv · 2021
  not yet assessed
• The trans-ancestral genomic architecture of glycemic traits. ↗

  UCL Discovery (University College London) · 2021
  not yet assessed
• Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease. ↗

  Research Square · 2021
  not yet assessed
• 189-LB: Using Genetics to Separate Childhood from Adult BMI Shows That Higher Childhood BMI Has No Direct Effect on Reduced Insulin Secretion or Sensitivity in Later Life ↗

  Diabetes · 2021
  not yet assessed
• 190-LB: Using Genetics to Uncouple Higher Adiposity from Its Adverse Metabolic Effects ↗

  Diabetes · 2021
  not yet assessed
• Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior ↗

  Nature Human Behaviour · 2021 · PMID 34321615
  not yet assessed
• Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile

  e-space (Manchester Metropolitan University) · 2021
  not yet assessed
• Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a mendelian randomization analysis using outcomes in first-degree relatives ↗

  Yearbook of pediatric endocrinology · 2021
  not yet assessed
• Author response: Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation ↗

  2021
  not yet assessed
• Genetic Evidence for Different Adiposity Phenotypes and their Opposing Influence on Ectopic Fat and Risk of Cardiometabolic Disease ↗

  2021
  not yet assessed
• Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease. ↗

  Research Square · 2021
  not yet assessed
• Associations of genetic scores for birth weight with newborn size and later Anthropometric traits and cardiometabolic risk markers in South Asians ↗

  medRxiv · 2021
  not yet assessed
• Using human genetics to understand the disease impacts of testosterone in men and women ↗

  Nature Medicine · 2020 · PMID 32042192
  not yet assessed
• Phantasia–The psychological significance of lifelong visual imagery vividness extremes ↗

  Cortex · 2020 · PMID 32446532
  not yet assessed
• Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes ↗

  Circulation Genomic and Precision Medicine · 2020 · PMID 32397738
  not yet assessed
• Quantification of the overall contribution of gene-environment interaction for obesity-related traits ↗

  Nature Communications · 2020 · PMID 32170055
  not yet assessed
• Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity ↗

  Diabetes · 2020 · PMID 32917775
  not yet assessed
• Is disrupted sleep a risk factor for Alzheimer’s disease? Evidence from a two-sample Mendelian randomization analysis ↗

  International Journal of Epidemiology · 2020 · PMID 33150399
  not yet assessed
• Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits ↗

  PLoS Computational Biology · 2020 · PMID 32797044
  not yet assessed
• Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study ↗

  International Journal of Epidemiology · 2020 · PMID 32588049
  not yet assessed
• Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies ↗

  Biological Psychiatry · 2020 · PMID 32684367
  not yet assessed
• A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function ↗

  Diabetes · 2020 · PMID 31915152
  not yet assessed
• A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease ↗

  UNC Libraries · 2020
  not yet assessed
• Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity ↗

  The Journal of Clinical Endocrinology & Metabolism · 2020 · PMID 32944759
  not yet assessed
• A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape ↗

  UNC Libraries · 2020
  not yet assessed
• Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index ↗

  UNC Libraries · 2020
  not yet assessed
• Large Copy-Number Variants in UK Biobank Caused by Clonal Hematopoiesis May Confound Penetrance Estimates ↗

  The American Journal of Human Genetics · 2020 · PMID 32574563
  not yet assessed
• Genetic Evidence for a Normal-Weight "Metabolically Obese" Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes ↗

  UNC Libraries · 2020
  not yet assessed
• Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci ↗

  Oxford University Research Archive (ORA) (University of Oxford) · 2020
  not yet assessed
• The genetic architecture of type 2 diabetes ↗

  UNC Libraries · 2020
  not yet assessed
• Phantasia - the psychological significance of lifelong visual imagery vividness extremes ↗

  2020
  not yet assessed
• Genetic predictors of participation in optional components of UK Biobank ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ↗

  medRxiv · 2020
  not yet assessed
• The Trans-Ancestral Genomic Architecture of Glycaemic Traits ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome ↗

  medRxiv · 2020
  not yet assessed
• Assessing the causal role of sleep traits on glycated haemoglobin: a Mendelian randomization study ↗

  medRxiv · 2020
  not yet assessed
• Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity ↗

  2020
  not yet assessed
• Genome-wide associations for birth weight and correlations with adult disease ↗

  UNC Libraries · 2020
  not yet assessed
• 1907-P: Using Human Genetics to Test the Disease Consequences of Varying Testosterone Levels in Men and Women ↗

  Diabetes · 2020
  not yet assessed
• Decision letter: Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian randomisation ↗

  2020
  not yet assessed
• Genetic risk for obesity is partially mediated by individual eating behaviours disinhibition and hunger, but not restraint ↗

  Appetite · 2020
  not yet assessed
• A genome wide association study of frozen shoulder identifies a common variant of <i>WNT7B</i> and diabetes as causal risk factors ↗

  medRxiv · 2020
  not yet assessed
• Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives ↗

  medRxiv · 2020
  not yet assessed
• Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity ↗

  2020
  not yet assessed
• Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity ↗

  2020
  not yet assessed
• Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes ↗

  UNC Libraries · 2020
  not yet assessed
• Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ↗

  UNC Libraries · 2020
  not yet assessed
• An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans ↗

  UNC Libraries · 2020
  not yet assessed
• A reference panel of 64,976 haplotypes for genotype imputation ↗

  UNC Libraries · 2020
  not yet assessed
• Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits ↗

  Digital Commons@Becker (Washington University School of Medicine) · 2020
  not yet assessed
• Genome-wide meta-analysis of common variant differences between men and women ↗

  UNC Libraries · 2020
  not yet assessed
• Testing the role of predicted gene knockouts in human anthropometric trait variation ↗

  UNC Libraries · 2020
  not yet assessed
• Across-cohort QC analyses of GWAS summary statistics from complex traits ↗

  UNC Libraries · 2020
  not yet assessed
• Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms ↗

  Nature Communications · 2019 · PMID 30696823
  not yet assessed
• Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates ↗

  Nature Communications · 2019 · PMID 30846698
  not yet assessed
• Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors ↗

  Nature Genetics · 2019 · PMID 31043758
  not yet assessed
• Biological and clinical insights from genetics of insomnia symptoms ↗

  Nature Genetics · 2019 · PMID 30804566
  not yet assessed
• Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits ↗

  Nature Communications · 2019 · PMID 31341166
  not yet assessed
• Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour ↗

  Nature Communications · 2019 · PMID 30952852
  not yet assessed
• Genetic correlates of social stratification in Great Britain ↗

  Nature Human Behaviour · 2019 · PMID 31636407
  not yet assessed
• Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study ↗

  PLoS Medicine · 2019 · PMID 30703100
  not yet assessed
• Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes ↗

  Nature Communications · 2019 · PMID 31409809
  not yet assessed
• Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting ↗

  The American Journal of Human Genetics · 2019 · PMID 30665703
  not yet assessed
• Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study ↗

  BMJ · 2019 · PMID 31243001
  not yet assessed
• GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI ↗

  Science Advances · 2019 · PMID 31840077
  not yet assessed
• Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci ↗

  Molecular Psychiatry · 2019 · PMID 30617275
  not yet assessed
• Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ↗

  Nature Genetics · 2019 · PMID 30778226
  not yet assessed
• Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data ↗

  Scientific Reports · 2019 · PMID 31316157
  not yet assessed
• Effects of body mass index on relationship status, social contact and socio-economic position: Mendelian randomization and within-sibling study in UK Biobank ↗

  International Journal of Epidemiology · 2019 · PMID 31800047
  not yet assessed
• Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans ↗

  Scientific Reports · 2019 · PMID 30926824
  not yet assessed
• Genome-wide association analyses of chronotype in 697, 828 individuals provides insights into circadian rhythms ↗

  Yearbook of pediatric endocrinology · 2019
  not yet assessed
• Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology ↗

  The American Journal of Human Genetics · 2019 · PMID 31178129
  not yet assessed
• A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin–creatinine ratio ↗

  Human Molecular Genetics · 2019 · PMID 31630189
  not yet assessed
• Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes ↗

  Sleep Medicine · 2019
  not yet assessed
• GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. ↗

  Apollo (University of Cambridge) · 2019
  not yet assessed
• Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

  Kölner Universitäts PublikationsServer (Universität zu Köln) · 2019
  not yet assessed
• Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ↗

  Nature Genetics · 2019
  not yet assessed
• Is disrupted sleep a risk factor for Alzheimer’s disease? Evidence from a two-sample Mendelian randomization analysis ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• Correction: Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

  Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) · 2019
  not yet assessed
• Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• Machine Learning based histology phenotyping to investigate epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• 0824 Using Mendelian Randomization To Understand How Chronotype Influences Breast Cancer Risk ↗

  SLEEP · 2019
  not yet assessed
• Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology ↗

  The American Journal of Human Genetics · 2019
  not yet assessed
• 2DOES HIGH BMI IN THE ABSENCE OF METABOLIC CONSEQUENCES CAUSE DEPRESSION? ↗

  European Neuropsychopharmacology · 2019
  not yet assessed
• Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

  Data Archiving and Networked Services (DANS) · 2019
  not yet assessed
• GENOME-WIDE ASSOCIATION ANALYSIS OF SELF-REPORTED DAYTIME SLEEPINESS IDENTIFIES 42 LOCI THAT SUGGEST BIOLOGICAL SUBTYPES

  STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) · 2019
  not yet assessed
• Does eating behaviour mediate genetic susceptibility to a higher BMI among young adults? ↗

  Obesity Abstracts · 2019
  not yet assessed
• M38 USING GENETICS TO UNDERSTAND THE CAUSAL EFFECT OF DYSLIPIDAEMIA ON DEPRESSION ↗

  European Neuropsychopharmacology · 2019
  not yet assessed
• GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

  UEF eRepo (University of Eastern Finland) · 2019
  not yet assessed
• PTU-050 Modifiable risk factors for gastro-oesophagal reflux disease: a mendelian randomisation study ↗

  2019
  not yet assessed
• Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics ↗

  publish.UP (University of Potsdam) · 2019
  not yet assessed
• Coding Variant In&amp;nbsp; &lt;i&gt;LEP&lt;/i&gt;&amp;nbsp;Associated with Lower Leptin Concentrations Implicates Leptin in the Regulation of Early Adiposity ↗

  SSRN Electronic Journal · 2019
  not yet assessed
• Contributors ↗

  Elsevier eBooks · 2019
  not yet assessed
• Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry ↗

  Human Molecular Genetics · 2018 · PMID 30124842
  not yet assessed
• Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps ↗

  Nature Genetics · 2018 · PMID 30297969
  not yet assessed
• Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry ↗

  Human Molecular Genetics · 2018 · PMID 30239722
  not yet assessed
• Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes ↗

  Nature Communications · 2018 · PMID 30054458
  not yet assessed
• Estimating sleep parameters using an accelerometer without sleep diary ↗

  Scientific Reports · 2018 · PMID 30154500
  not yet assessed
• Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood ↗

  Nature Communications · 2018 · PMID 29891976
  not yet assessed
• Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes ↗

  Nature Genetics · 2018 · PMID 29632382
  not yet assessed
• Genome Analyses of &gt;200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders ↗

  The American Journal of Human Genetics · 2018 · PMID 30388399
  not yet assessed
• Using genetics to understand the causal influence of higher BMI on depression ↗

  International Journal of Epidemiology · 2018 · PMID 30423117
  not yet assessed
• Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics ↗

  Human Molecular Genetics · 2018 · PMID 29309628
  not yet assessed
• A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes ↗

  Diabetes · 2018 · PMID 29703844
  not yet assessed
• Mosaic Turner syndrome shows reduced penetrance in an adult population study ↗

  Genetics in Medicine · 2018 · PMID 30181606
  not yet assessed
• Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension ↗

  Diabetes · 2018 · PMID 30352878
  not yet assessed
• A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure ↗

  Cell Reports · 2018 · PMID 29641994
  not yet assessed
• Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use ↗

  Biological Psychiatry · 2018 · PMID 30679032
  not yet assessed
• Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference ↗

  Nature Communications · 2018 · PMID 29459775
  not yet assessed
• Mendelian randomisation in type 2 diabetes and coronary artery disease ↗

  Current Opinion in Genetics & Development · 2018 · PMID 29935421
  not yet assessed
• Response to Prakash et al. ↗

  Genetics in Medicine · 2018 · PMID 30573795
  not yet assessed
• Physical Inactivity and Sleep Inefficiency Accentuate the Genetic Risk of Obesity ↗

  Diabetes · 2018
  not yet assessed
• Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Meta-analysis of genome-wide association studies for height and body mass index in ∼700,000 individuals of European ancestry ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Estimating sleep parameters using an accelerometer without sleep diary ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• 0015 Biological And Clinical Insights from Genetics of Insomnia Symptoms ↗

  SLEEP · 2018
  not yet assessed
• Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Protein-Coding Variants Implicate Novel Genes Related to Lipid Homeostasis Contributing to Body Fat Distribution ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Genetic Consequences of Social Stratification in Great Britain ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ↗

  Nature Genetics · 2018 · PMID 29549329
  not yet assessed
• Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ↗

  Nature Genetics · 2018 · PMID 29549330
  not yet assessed
• Biological and clinical insights from genetics of insomnia symptoms ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Assessing the pathogenicity, penetrance and expressivity of putative disease-causing variants in a population setting ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls ↗

  Scientific Data · 2018
  not yet assessed
• Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• 432 Investigating a causal relationship between body mass index and inflammatory skin disease using mendelian randomisation ↗

  Journal of Investigative Dermatology · 2018
  not yet assessed
• 0013 Genome-wide Association Analysis Identifies &gt;75 Genetic Loci Associated With Sleep Duration In UK Biobank Participants ↗

  SLEEP · 2018
  not yet assessed
• 0014 Genome-wide Association Analysis Of Excessive Daytime Sleepiness In The Uk Biobank Identifies 42 Novel Loci ↗

  SLEEP · 2018
  not yet assessed
• 0055 Genome-Wide Association Analysis of Accelerometer-Derived Traits Reveals Novel Genetic Loci Associated with Rest-Activity Patterns in the UK Biobank ↗

  SLEEP · 2018
  not yet assessed
• Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. ↗

  Kölner Universitäts PublikationsServer (Universität zu Köln) · 2018
  not yet assessed
• Genome-Wide and Abdominal Imaging Data Characterizes Common Alleles Associated with Higher BMI and Subcutaneous Fat but Less Liver Fat and Lower Risk of Type 2 Diabetes ↗

  Diabetes · 2018
  not yet assessed
• Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans ↗

  Diabetes · 2017 · PMID 28566273
  not yet assessed
• Rare and low-frequency coding variants alter human adult height ↗

  Nature · 2017 · PMID 28146470
  not yet assessed
• Exome-wide association study of plasma lipids in &gt;300,000 individuals ↗

  Nature Genetics · 2017 · PMID 29083408
  not yet assessed
• Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity ↗

  Nature Genetics · 2017 · PMID 29273807
  not yet assessed
• Genetic evidence of assortative mating in humans ↗

  Nature Human Behaviour · 2017
  not yet assessed
• Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ↗

  PLoS Genetics · 2017 · PMID 28448500
  not yet assessed
• Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits ↗

  Nature Communications · 2017 · PMID 28443625
  not yet assessed
• Rare and low-frequency coding variants alter human adult height ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2017
  not yet assessed
• A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants ↗

  Diabetes · 2017 · PMID 28490609
  not yet assessed
• Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease ↗

  Journal of the American Heart Association · 2017 · PMID 28550093
  not yet assessed
• Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development ↗

  The American Journal of Human Genetics · 2017 · PMID 29290336
  not yet assessed
• CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ↗

  Nature Communications · 2017 · PMID 28963451
  not yet assessed
• Exome-wide association study of plasma lipids in > 300,000 individuals

  Figshare · 2017
  not yet assessed
• Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers ↗

  PLoS ONE · 2017 · PMID 28957414
  not yet assessed
• A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk ↗

  Diabetes · 2017 · PMID 28341696
  not yet assessed
• Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees ↗

  Proceedings of the National Academy of Sciences · 2017 · PMID 29279374
  not yet assessed
• Influence of cell distribution and diabetes status on the association between mitochondrial <scp>DNA</scp> copy number and aging phenotypes in the In<scp>CHIANTI</scp> study ↗

  Aging Cell · 2017 · PMID 29047204
  not yet assessed
• A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk ↗

  University of Southern Denmark Research Portal (University of Southern Denmark) · 2017
  not yet assessed
• Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits ↗

  Tampere University Institutional Repository (Tampere University) · 2017
  not yet assessed
• Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. ↗

  Duo Research Archive (University of Oslo) · 2017
  not yet assessed
• Rare and low-frequency coding variants alter human adult height ↗

  Apollo (University of Cambridge) · 2017
  not yet assessed
• Sequence data and association statistics from 12,940 type 2 diabetes cases and controls ↗

  Scientific Data · 2017 · PMID 29257133
  not yet assessed
• Erratum: Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance ↗

  Nature Genetics · 2017
  not yet assessed
• Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults ↗

  PLoS Genetics · 2017 · PMID 28832619
  not yet assessed
• Mosaic Turner syndrome shows reduced phenotypic penetrance in an adult population study compared to clinically ascertained cases ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Phenotypes associated with female X chromosome aneuploidy in UK Biobank: an unselected, adult, population-based cohort

  2017
  not yet assessed
• Causal analyses, statistical efficiency and phenotypic precision through Recall-by-Genotype study design ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Narrow-sense heritability estimation of complex traits using identity-by-descent information ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• Emotional and external eating and eating architecture in the UK ↗

  Proceedings of The Nutrition Society · 2017
  not yet assessed
• Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2017
  not yet assessed
• A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2017
  not yet assessed
• Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. ↗

  Apollo (University of Cambridge) · 2017
  not yet assessed
• An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2017
  not yet assessed
• Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers: Genetic influences on Red Blood Cell variation

  2017
  not yet assessed
• The genetic architecture of type 2 diabetes ↗

  Nature · 2016 · PMID 27398621
  not yet assessed
• Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance ↗

  Nature Genetics · 2016 · PMID 27841877
  not yet assessed
• Genome-wide associations for birth weight and correlations with adult disease ↗

  Nature · 2016 · PMID 27680694
  not yet assessed
• Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function ↗

  Nature Communications · 2016 · PMID 26831199
  not yet assessed
• Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci ↗

  PLoS Genetics · 2016 · PMID 27494321
  not yet assessed
• Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank ↗

  BMJ · 2016 · PMID 26956984
  not yet assessed
• Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight ↗

  JAMA · 2016 · PMID 26978208
  not yet assessed
• Gene–obesogenic environment interactions in the UK Biobank study ↗

  International Journal of Epidemiology · 2016 · PMID 28073954
  not yet assessed
• Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels ↗

  Nature Communications · 2016 · PMID 26833098
  not yet assessed
• Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease ↗

  Diabetes · 2016 · PMID 27207519
  not yet assessed
• Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants ↗

  Aging · 2016 · PMID 27015805
  not yet assessed
• A genomic approach to therapeutic target validation identifies a glucose-lowering <i>GLP1R</i> variant protective for coronary heart disease ↗

  Science Translational Medicine · 2016 · PMID 27252175
  not yet assessed
• Prosaposin is a regulator of progranulin levels and oligomerization ↗

  Nature Communications · 2016 · PMID 27356620
  not yet assessed
• Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies <i>BCL2</i> and <i>FAM19A2</i> as Novel Insulin Sensitivity Loci ↗

  Diabetes · 2016 · PMID 27416945
  not yet assessed
• Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index ↗

  Molecular Psychiatry · 2016 · PMID 27184124
  not yet assessed
• A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape ↗

  Nature Communications · 2016 · PMID 27876822
  not yet assessed
• Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively ↗

  Diabetologia · 2016 · PMID 26961502
  not yet assessed
• Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health ↗

  Human Reproduction · 2016 · PMID 26732621
  not yet assessed
• Quantifying the extent to which index event biases influence large genetic association studies ↗

  Human Molecular Genetics · 2016 · PMID 28040731
  not yet assessed
• Across-cohort QC analyses of GWAS summary statistics from complex traits ↗

  European Journal of Human Genetics · 2016 · PMID 27552965
  not yet assessed
• A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies ↗

  The American Journal of Human Genetics · 2016 · PMID 27087321
  not yet assessed
• International cancer seminars: a focus on kidney cancer ↗

  Annals of Oncology · 2016 · PMID 27130845
  not yet assessed
• Analysis with the exome array identifies multiple new independent variants in lipid loci ↗

  Human Molecular Genetics · 2016 · PMID 27466198
  not yet assessed
• Functional characterisation of ADIPOQ variants using individuals recruited by genotype ↗

  Molecular and Cellular Endocrinology · 2016 · PMID 26996131
  not yet assessed
• Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene ↗

  Journal of Clinical Investigation · 2016
  not yet assessed
• Testing the role of predicted gene knockouts in human anthropometric trait variation ↗

  Human Molecular Genetics · 2016 · PMID 26908616
  not yet assessed
• Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2016
  not yet assessed
• Independent test assessment using the extreme value distribution theory ↗

  BMC Proceedings · 2016 · PMID 27980644
  not yet assessed
• Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight ↗

  Obstetrical & Gynecological Survey · 2016
  not yet assessed
• Human Longevity is Influenced by Many Genetic Variants: Evidence from 75,000 UK Biobank Participants ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2016
  not yet assessed
• Genome-wide association analyses in &gt; 119,000 individuals identifies thirteen morningness and two sleep duration loci ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2016
  not yet assessed
• Quantifying the extent to which index event biases influence large genetic association studies ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2016
  not yet assessed
• Evidence that lower socioeconomic position accentuates genetic susceptibility to obesity ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2016
  not yet assessed
• Authors’ reply to Toth ↗

  BMJ · 2016 · PMID 27048594
  not yet assessed
• Diabetes tipo MODY La contribución de la diabetes tipo MODY a nuestros conocimientos sobre los mecanismos moleculares que intervienen en la diabetes tipo 2

  2016
  not yet assessed
• Causal Inference in Medicine via Mendelian Randomization ↗

  2016
  not yet assessed
• Strategies for improving statistical power for detailed physiological characterisation of individuals with type 2 diabetes-associated variants

  Diabetologia · 2016
  not yet assessed
• Causal Relationship between Obesity and Vitamin D Status

  2016
  not yet assessed
• Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels ↗

  University of Southern Denmark Research Portal (University of Southern Denmark) · 2016
  not yet assessed
• The genetic architecture of type 2 diabetes. ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2016
  not yet assessed
• Abstract MP83: Exomechip Meta-analysis of 526,508 Individuals From Five Ancestries Identifies Coding Variation in <i>MC4R</i> and <i>KSR2</i> Associated with Body Mass Index ↗

  Circulation · 2016
  not yet assessed
• Why life is tougher for short men and overweight women ↗

  2016
  not yet assessed
• Genetic studies of body mass index yield new insights for obesity biology ↗

  Nature · 2015 · PMID 25673413
  not yet assessed
• New genetic loci link adipose and insulin biology to body fat distribution ↗

  Nature · 2015 · PMID 25673412
  not yet assessed
• Biological interpretation of genome-wide association studies using predicted gene functions ↗

  Nature Communications · 2015 · PMID 25597830
  not yet assessed
• Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci ↗

  Nature Genetics · 2015 · PMID 26551672
  not yet assessed
• Population genetic differentiation of height and body mass index across Europe ↗

  Nature Genetics · 2015 · PMID 26366552
  not yet assessed
• Directional dominance on stature and cognition in diverse human populations ↗

  Nature · 2015 · PMID 26131930
  not yet assessed
• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility ↗

  Nature Communications · 2015 · PMID 25631608
  not yet assessed
• Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene ↗

  Journal of Clinical Investigation · 2015 · PMID 25798622
  not yet assessed
• Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity ↗

  Nature Genetics · 2015 · PMID 26098870
  not yet assessed
• Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes ↗

  Diabetes · 2015 · PMID 25948681
  not yet assessed
• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2015
  not yet assessed
• Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals ↗

  Human Molecular Genetics · 2015 · PMID 25784503
  not yet assessed
• Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at <i>CCND2</i> Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion ↗

  Diabetes · 2015 · PMID 25605810
  not yet assessed
• An Ant Colony Optimization and Tabu List Approach to the Detection of Gene-Gene Interactions in Genome-Wide Association Studies [Research Frontier] ↗

  IEEE Computational Intelligence Magazine · 2015
  not yet assessed
• Ant colony optimisation of decision tree and contingency table models for the discovery of gene–gene interactions ↗

  IET Systems Biology · 2015 · PMID 26577156
  not yet assessed
• Across-cohort QC analyses of genome-wide association study summary statistics from complex traits ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2015
  not yet assessed
• Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause, and impact reproductive health: a UK Biobank study ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2015
  not yet assessed
• A reference panel of 64,976 haplotypes for genotype imputation ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2015
  not yet assessed
• Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2015
  not yet assessed
• The Hunt for Low-Frequency Alleles Predisposing to Type 2 Diabetes and Related Cardiovascular Risk Factors ↗

  Current Cardiovascular Risk Reports · 2015
  not yet assessed
• and type 2 diabetes respectively

  2015
  not yet assessed
• Directional dominance on stature and cognition in diverse human populations ↗

  Archive ouverte UNIGE (University of Geneva) · 2015
  not yet assessed
• at menopause, and impact reproductive health: a UK Biobank study

  2015
  not yet assessed
• Variants in the <i>FTO</i> and <i>CDKAL1</i> loci have recessive effects on risk of obesity and type 2 diabetes respectively ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2015
  not yet assessed
• Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2015
  not yet assessed
• LD relationship for &lt;i&gt;FTO&lt;/i&gt; Association SNPs and rs7202116. ↗

  INDIGO (University of Illinois at Chicago) · 2015
  not yet assessed
• Defining the role of common variation in the genomic and biological architecture of adult human height ↗

  Nature Genetics · 2014
  not yet assessed
• Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility ↗

  Nature Genetics · 2014 · PMID 24509480
  not yet assessed
• Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study ↗

  The Lancet Diabetes & Endocrinology · 2014 · PMID 24974252
  not yet assessed
• Differences in smoking associated DNA methylation patterns in South Asians and Europeans ↗

  Clinical Epigenetics · 2014 · PMID 24485148
  not yet assessed
• Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes ↗

  Diabetes · 2014 · PMID 25048195
  not yet assessed
• Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease ↗

  PLoS Genetics · 2014 · PMID 24586183
  not yet assessed
• A Central Role for GRB10 in Regulation of Islet Function in Man ↗

  PLoS Genetics · 2014 · PMID 24699409
  not yet assessed
• Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity ↗

  Diabetes · 2014 · PMID 24947364
  not yet assessed
• Rare variants in <i>PPARG</i> with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes ↗

  Proceedings of the National Academy of Sciences · 2014 · PMID 25157153
  not yet assessed
• A novel common variant in DCST2 is associated with length in early life and height in adulthood ↗

  Human Molecular Genetics · 2014 · PMID 25281659
  not yet assessed
• Another explanation for apparent epistasis ↗

  Nature · 2014 · PMID 25279928
  not yet assessed
• Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms ↗

  Cell · 2014 · PMID 24439387
  not yet assessed
• Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers ↗

  PLoS Genetics · 2014 · PMID 25474695
  not yet assessed
• A Genetic Variant in the Seed Region of miR-4513 Shows Pleiotropic Effects on Lipid and Glucose Homeostasis, Blood Pressure, and Coronary Artery Disease ↗

  Human Mutation · 2014 · PMID 25256095
  not yet assessed
• Statins and type 2 diabetes: genetic studies on target ↗

  The Lancet · 2014 · PMID 25262342
  not yet assessed
• Simulation of Finnish Population History, Guided by Empirical Genetic Data, to Assess Power of Rare-Variant Tests in Finland ↗

  The American Journal of Human Genetics · 2014 · PMID 24768551
  not yet assessed
• Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes ↗

  Human Molecular Genetics · 2014 · PMID 25378555
  not yet assessed
• Ant colony optimisation of decision trees for the detection of gene-gene interactions ↗

  2014
  not yet assessed
• Evaluation of Common Type 2 Diabetes Risk Variants in a South Asian Population of Sri Lankan Descent ↗

  PLoS ONE · 2014 · PMID 24926958
  not yet assessed
• Physiology Helps GWAS Take a Step Closer to Mechanism ↗

  Diabetes · 2014 · PMID 24853896
  not yet assessed
• Cell specific eQTL analysis without sorting cells ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2014
  not yet assessed
• Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

  UWA Profiles and Research Repository (University of Western Australia) · 2014
  not yet assessed
• Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

  2014
  not yet assessed
• Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

  UWA Profiles and Research Repository (University of Western Australia) · 2014
  not yet assessed
• Systematic identification of trans eQTLs as putative drivers of known disease associations ↗

  Nature Genetics · 2013 · PMID 24013639
  not yet assessed
• Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture ↗

  Nature Genetics · 2013 · PMID 23563607
  not yet assessed
• Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits ↗

  PLoS Genetics · 2013 · PMID 23754948
  not yet assessed
• Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach ↗

  Diabetes · 2013 · PMID 23884885
  not yet assessed
• A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function ↗

  PLoS Genetics · 2013 · PMID 23408906
  not yet assessed
• Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes ↗

  Diabetes · 2013 · PMID 23835345
  not yet assessed
• Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes ↗

  Diabetes · 2013 · PMID 23378610
  not yet assessed
• Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study ↗

  International Journal of Epidemiology · 2013 · PMID 24336895
  not yet assessed
• Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation ↗

  PLoS ONE · 2013 · PMID 23696881
  not yet assessed
• Genetic variation associated with circulating monocyte count in the eMERGE Network ↗

  Human Molecular Genetics · 2013 · PMID 23314186
  not yet assessed
• The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts ↗

  BMC Genomics · 2013 · PMID 24044605
  not yet assessed
• Recent progress in the use of genetics to understand links between type 2 diabetes and related metabolic traits ↗

  Genome biology · 2013 · PMID 23548046
  not yet assessed
• Subset-based ant colony optimisation for the discovery of gene-gene interactions in genome wide association studies ↗

  2013
  not yet assessed
• Ant Colony Optimisation for Exploring Logical Gene-Gene Associations in Genome Wide Association Studies.

  Open Research Exeter (University of Exeter) · 2013
  not yet assessed
• Genetic and Functional Analyses Identify NAT2 as a Human Insulin Sensitivity Gene

  Circulation · 2013
  not yet assessed
• DNA methylation, cardio metabolic risk and type 2 diabetes in south Asians and Europeans

  Bristol Research (University of Bristol) · 2013
  not yet assessed
• Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits ↗

  Tampere University Institutional Repository (Tampere University) · 2013
  not yet assessed
• Correction: The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits ↗

  PLoS Genetics · 2013
  not yet assessed
• Supplementary Material 15

  2013
  not yet assessed
• Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes ↗

  Nature Genetics · 2012 · PMID 22885922
  not yet assessed
• Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits ↗

  Nature Genetics · 2012 · PMID 22426310
  not yet assessed
• Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals ↗

  PLoS Genetics · 2012 · PMID 22479202
  not yet assessed
• The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits ↗

  PLoS Genetics · 2012 · PMID 22876189
  not yet assessed
• FTO genotype is associated with phenotypic variability of body mass index ↗

  Nature · 2012 · PMID 22982992
  not yet assessed
• Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases ↗

  PLoS Genetics · 2012 · PMID 22693455
  not yet assessed
• A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation ↗

  PLoS Genetics · 2012 · PMID 22829776
  not yet assessed
• Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes ↗

  Diabetologia · 2012 · PMID 23160641
  not yet assessed
• Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight ↗

  Human Molecular Genetics · 2012 · PMID 22956269
  not yet assessed
• Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis ↗

  The American Journal of Human Genetics · 2012 · PMID 23022100
  not yet assessed
• Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M Variant ↗

  PLoS ONE · 2012 · PMID 22724004
  not yet assessed
• Genome-wide meta-analysis of common variant differences between men and women ↗

  Human Molecular Genetics · 2012 · PMID 22843499
  not yet assessed
• Deep Resequencing Unveils Genetic Architecture of <i>ADIPOQ</i> and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation ↗

  Diabetes · 2012 · PMID 22403302
  not yet assessed
• Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis ↗

  Diabetologia · 2012 · PMID 22538361
  not yet assessed
• Are the causes of obesity primarily environmental? No ↗

  BMJ · 2012 · PMID 22968529
  not yet assessed
• Preterm Birth Genome Project (PGP) – validation of resources for preterm birth genome-wide studies ↗

  Journal of Perinatal Medicine · 2012 · PMID 23096097
  not yet assessed
• Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2012
  not yet assessed
• Genome-Wide Association Study to Identify Common Variants Associated with Brachial Circumference: A Meta-Analysis of 14 Cohorts ↗

  PLoS ONE · 2012 · PMID 22479309
  not yet assessed
• P128 Identification de nouveaux polymorphismes génétiques associés au risque de diabète de type 2 chez les obèses et non obèses européens ↗

  Diabetes & Metabolism · 2012
  not yet assessed
• Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

  Digital Access to Scholarship at Harvard (DASH) (Harvard University) · 2012
  not yet assessed
• Genome-wide meta-analysis of common variant differences between men and women ↗

  University of Regensburg Publication Server (University of Regensburg) · 2012
  not yet assessed
• A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone-Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation

  Tampere University Institutional Repository (Tampere University) · 2012
  not yet assessed
• Common variants at 12q15 and 12q24 are associated with infant head circumference ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2012
  not yet assessed
• FTO genotype is associated with phenotypic variability of body mass index

  University of Regensburg Publication Server (University of Regensburg) · 2012
  not yet assessed
• A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple loci implicated in s

  2012
  not yet assessed
• Abstract 10916: Mendelian Randomization Studies Do Not Support a Causal Effect of Plasma Lipids on Insulin Sensitivity

  Circulation · 2012
  not yet assessed
• Genomic inflation factors under polygenic inheritance ↗

  European Journal of Human Genetics · 2011 · PMID 21407268
  not yet assessed
• Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci ↗

  Nature Genetics · 2011 · PMID 21874001
  not yet assessed
• Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes ↗

  Diabetes · 2011 · PMID 21873549
  not yet assessed
• Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing ↗

  Aging Cell · 2011 · PMID 21668623
  not yet assessed
• Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study ↗

  Human Molecular Genetics · 2011 · PMID 21378095
  not yet assessed
• People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population ↗

  European Journal of Human Genetics · 2011 · PMID 21829225
  not yet assessed
• Multiple Loci Are Associated with White Blood Cell Phenotypes ↗

  PLoS Genetics · 2011 · PMID 21738480
  not yet assessed
• Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index ↗

  International Journal of Epidemiology · 2011 · PMID 21593077
  not yet assessed
• Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance ↗

  Diabetes · 2011 · PMID 21282362
  not yet assessed
• Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms ↗

  PLoS Genetics · 2011 · PMID 21533175
  not yet assessed
• An <i>FTO</i> variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference ↗

  Diabetic Medicine · 2011 · PMID 21294771
  not yet assessed
• Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association ↗

  Human Molecular Genetics · 2011 · PMID 21798870
  not yet assessed
• Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals ↗

  PLoS Genetics · 2011 · PMID 22242009
  not yet assessed
• Adult height variants affect birth length and growth rate in children ↗

  Human Molecular Genetics · 2011 · PMID 21757498
  not yet assessed
• A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement ↗

  European Journal of Endocrinology · 2011 · PMID 21317282
  not yet assessed
• Piecing together the FTO jigsaw ↗

  Genome biology · 2011 · PMID 21349207
  not yet assessed
• Sequencing <i>PDX1</i> (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes ↗

  Diabetic Medicine · 2011 · PMID 21569088
  not yet assessed
• Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution ↗

  Nature Genetics · 2011
  not yet assessed
• Erratum: Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis ↗

  Nature Genetics · 2011
  not yet assessed
• Recent Progress in Identifying Genes Contributing to Type 2 Diabetes and Metabolic Syndrome ↗

  2011
  not yet assessed
• Identifying likely causal connections between gene expression levels using a Mendelian randomization approach ↗

  Clinical Biochemistry · 2011
  not yet assessed
• Genomic inflation factors under polygenic inheritance

  Queensland's institutional digital repository (The University of Queensland) · 2011
  not yet assessed
• EIGHT COMMON GENETIC VARIANTS ASSOCIATED WITH SERUM DHEAS LEVELS SUGGESTS A KEY ROLE IN AGEING MECHANISMS

  Research Portal (King's College London) · 2011
  not yet assessed
• PREDICTING 5-AMINOSALICYLATE NEPHROTOXICITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE.

  2011
  not yet assessed
• Genetic Basis for Gestation Length

  Oxford University Research Archive (ORA) (University of Oxford) · 2011
  not yet assessed
• Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ↗

  Nature Genetics · 2010 · PMID 20935630
  not yet assessed
• Hundreds of variants clustered in genomic loci and biological pathways affect human height ↗

  Nature · 2010 · PMID 20881960
  not yet assessed
• Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis ↗

  Nature Genetics · 2010 · PMID 20581827
  not yet assessed
• Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution ↗

  Nature Genetics · 2010
  not yet assessed
• Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls ↗

  Nature · 2010 · PMID 20360734
  not yet assessed
• Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2010
  not yet assessed
• C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization ↗

  International Journal of Obesity · 2010 · PMID 20714329
  not yet assessed
• Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight ↗

  Nature Genetics · 2010 · PMID 20372150
  not yet assessed
• Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus ↗

  PLoS ONE · 2010 · PMID 21124985
  not yet assessed
• Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Common Genetic Variants in <i>GCK</i> and <i>TCF7L2</i> Are Associated With Fasting and Postchallenge Glucose Levels in Pregnancy and With the New Consensus Definition of Gestational Diabetes Mellitus From the International Association of Diabetes and Pregnancy Study Groups ↗

  Diabetes · 2010 · PMID 20682688
  not yet assessed
• Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes ↗

  BMC Medical Genetics · 2010 · PMID 20459604
  not yet assessed
• Genome-Wide Association Scan Allowing for Epistasis in Type 2 Diabetes ↗

  Annals of Human Genetics · 2010 · PMID 21133856
  not yet assessed
• Ant colony optimisation to identify genetic variant association with type 2 diabetes ↗

  Information Sciences · 2010
  not yet assessed
• A role for coding functional variants in HNF4A in type 2 diabetes susceptibility ↗

  Diabetologia · 2010 · PMID 20878384
  not yet assessed
• Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits ↗

  Current Opinion in Lipidology · 2010 · PMID 19956073
  not yet assessed
• Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus ↗

  Clinical & Experimental Immunology · 2010 · PMID 20528885
  not yet assessed
• The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI ↗

  BMC Medical Genetics · 2010 · PMID 20929593
  not yet assessed
• Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk ↗

  Nature Genetics · 2010
  not yet assessed
• Hundreds of variants clustered in genomic loci and biological pathways affect human height

  UWA Profiles and Research Repository (University of Western Australia) · 2010
  not yet assessed
• Role of low frequency variants in HNF1A exons 8-10 encoding hepatocyte nuclear factor-1 alpha isoform A to susceptibility to Type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2010
  not yet assessed
• Common Variation in the DIO2 Gene Predicts Baseline Psychological Well-Being and Response to Combination Thyroxine Plus Triiodothyronine Therapy in Hypothyroid Patients ↗

  The Journal of Clinical Endocrinology & Metabolism · 2009 · PMID 19190113
  not yet assessed
• Common Variation in the β-Carotene 15,15′-Monooxygenase 1 Gene Affects Circulating Levels of Carotenoids: A Genome-wide Association Study ↗

  The American Journal of Human Genetics · 2009 · PMID 19185284
  not yet assessed
• Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes ↗

  Human Molecular Genetics · 2009 · PMID 19933169
  not yet assessed
• Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution ↗

  PLoS Genetics · 2009 · PMID 19557161
  not yet assessed
• A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels ↗

  PLoS Genetics · 2009 · PMID 20011104
  not yet assessed
• Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: Results of genome-wide association analyses including 4659 European individuals ↗

  Atherosclerosis · 2009 · PMID 20018283
  not yet assessed
• A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy ↗

  Human Molecular Genetics · 2009 · PMID 19429911
  not yet assessed
• Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth ↗

  Diabetes · 2009 · PMID 19228808
  not yet assessed
• Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach ↗

  Diabetes · 2009 · PMID 19252133
  not yet assessed
• Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants? ↗

  Diabetologia · 2009 · PMID 19526209
  not yet assessed
• FTOgene variation and measures of body mass in an African population ↗

  BMC Medical Genetics · 2009 · PMID 19265514
  not yet assessed
• The 9p21 Myocardial Infarction Risk Allele Increases Risk of Peripheral Artery Disease in Older People ↗

  Circulation Cardiovascular Genetics · 2009 · PMID 20031606
  not yet assessed
• Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response ↗

  Diabetologia · 2009 · PMID 19455304
  not yet assessed
• Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations ↗

  American Journal of Epidemiology · 2009 · PMID 19602701
  not yet assessed
• A powerful approach to sub‐phenotype analysis in population‐based genetic association studies ↗

  Genetic Epidemiology · 2009 · PMID 20039379
  not yet assessed
• Polygenic Risk Variants for Type 2 Diabetes Susceptibility Modify Age at Diagnosis in Monogenic <i>HNF1A</i> Diabetes ↗

  Diabetes · 2009 · PMID 19794065
  not yet assessed
• Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy ↗

  The Journal of Clinical Endocrinology & Metabolism · 2009 · PMID 19820008
  not yet assessed
• Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q ↗

  Diabetes · 2009 · PMID 19389826
  not yet assessed
• Circulating β-carotene levels and type 2 diabetes—cause or effect? ↗

  Diabetologia · 2009 · PMID 19662379
  not yet assessed
• The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or INCHIANTI studies ↗

  International Journal of Epidemiology · 2009 · PMID 19651761
  not yet assessed
• Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people ↗

  European Heart Journal · 2009 · PMID 19435741
  not yet assessed
• Genetic association analysis of LARS2 with type 2 diabetes ↗

  Diabetologia · 2009 · PMID 19847392
  not yet assessed
• Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy ↗

  Endocrinology · 2009
  not yet assessed
• Interleukin-18 Polymorphism and Physical Functioning in Older People: A Replication Study and Meta-Analysis ↗

  The Journals of Gerontology Series A · 2009 · PMID 19633236
  not yet assessed
• Low Frequency Variants in the Exons Only Encoding Isoform A of HNF1A Do Not Contribute to Susceptibility to Type 2 Diabetes ↗

  PLoS ONE · 2009 · PMID 19672314
  not yet assessed
• Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination T4/T3 therapy in patients on thyroid hormone replacement

  Society for Endocrinology BES 2009 · 2009
  not yet assessed
• Response to Comment On: Perry et al. (2009) Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach. Diabetes;58:1463–1467 ↗

  Diabetes · 2009
  not yet assessed
• (untitled)

  Edinburgh Research Explorer (University of Edinburgh) · 2009
  not yet assessed
• Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution ↗

  PLoS Genetics · 2009
  not yet assessed
• Commentary: A new dawn for genetic epidemiology? ↗

  International Journal of Epidemiology · 2009 · PMID 19584124
  not yet assessed
• Childhood Phenotypes Related to Adult Obesity: The Application of Genetic Risk Variants

  UCL Discovery (University College London) · 2009
  not yet assessed
• Mendelian Randomization Studies of the Role of Biomarkers in Type 2 Diabetes

  2009
  not yet assessed
• Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes ↗

  Nature Genetics · 2008 · PMID 18372903
  not yet assessed
• Common variants near MC4R are associated with fat mass, weight and risk of obesity ↗

  Nature Genetics · 2008 · PMID 18454148
  not yet assessed
• Genome-wide association analysis identifies 20 loci that influence adult height ↗

  Nature Genetics · 2008 · PMID 18391952
  not yet assessed
• A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs) ↗

  PLoS Genetics · 2008 · PMID 18464913
  not yet assessed
• Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes ↗

  The American Journal of Human Genetics · 2008 · PMID 18940312
  not yet assessed
• Common Variation in the <i>FTO</i> Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI ↗

  Diabetes · 2008 · PMID 18346983
  not yet assessed
• Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk ↗

  Diabetes · 2008 · PMID 18591388
  not yet assessed
• The fat mass–and obesity-associated locus and dietary intake in children ↗

  American Journal of Clinical Nutrition · 2008 · PMID 18842783
  not yet assessed
• FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians ↗

  Diabetologia · 2008 · PMID 19005641
  not yet assessed
• Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable ↗

  PLoS Medicine · 2008 · PMID 18336062
  not yet assessed
• A Common Variation in Deiodinase 1 Gene DIO1 Is Associated with the Relative Levels of Free Thyroxine and Triiodothyronine ↗

  The Journal of Clinical Endocrinology & Metabolism · 2008 · PMID 18492748
  not yet assessed
• Reaching new heights: insights into the genetics of human stature ↗

  Trends in Genetics · 2008 · PMID 18950892
  not yet assessed
• Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data ↗

  Diabetes · 2008 · PMID 19056611
  not yet assessed
• New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function ↗

  Current Opinion in Clinical Nutrition & Metabolic Care · 2008 · PMID 18541994
  not yet assessed
• A genetic link between type 2 diabetes and prostate cancer ↗

  Diabetologia · 2008 · PMID 18696045
  not yet assessed
• Beta cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles ↗

  Diabetologia · 2008 · PMID 18719881
  not yet assessed
• Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes ↗

  Diabetologia · 2008 · PMID 18853133
  not yet assessed
• Population-Specific Risk of Type 2 Diabetes Conferred by <i>HNF4A</i> P2 Promoter Variants ↗

  Diabetes · 2008 · PMID 18728231
  not yet assessed
• Filaggrin gene mutations are associated with asthma and eczema in later life ↗

  Journal of Allergy and Clinical Immunology · 2008 · PMID 18760831
  not yet assessed
• The association of common genetic variants in the APOA5, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits ↗

  Diabetologia · 2008 · PMID 19018513
  not yet assessed
• Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people ↗

  Neurobiology of Aging · 2008 · PMID 18848371
  not yet assessed
• Stratified analysis of the Wellcome Trust Case Control Consortium scan for type 2 diabetes reveals susceptibility loci that may affect age of diagnosis

  Oxford University Research Archive (ORA) (University of Oxford) · 2008
  not yet assessed
• Fine-mapping type 2 diabetes causal variants on chromosome 9p21 in 2000 UK cases and 3000 unselected controls

  Oxford University Research Archive (ORA) (University of Oxford) · 2008
  not yet assessed
• 365 SNPS ASSOCIATED WITH NORMAL VARIATION IN ADULT HUMAN HEIGHT ARE NOT ASSOCIATED WITH OSTEOARTHRITIS SUSCEPTIBILITY ↗

  Osteoarthritis and Cartilage · 2008
  not yet assessed
• The fat mass- and obesity-associated locus and dietary intake in children

  University of Brighton Repository (University of Brighton) · 2008
  not yet assessed
• A Mendelian randomisation study provides initial evidence that sex hormone binding globulin (SHBG) levels alter type 2 diabetes risk

  Diabetologia · 2008
  not yet assessed
• Large-scale type 2 diabetes association analysis of low-frequency nonsynonymous coding variants in the HNF4A gene including up to 17,600 individuals

  Oxford University Research Archive (ORA) (University of Oxford) · 2008
  not yet assessed
• Extended analysis of genome-wide scans provides clues about novel common and rare susceptibility loci for type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2008
  not yet assessed
• Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls ↗

  Nature · 2007 · PMID 17554300
  not yet assessed
• A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity ↗

  Science · 2007 · PMID 17434869
  not yet assessed
• Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes ↗

  Science · 2007 · PMID 17463249
  not yet assessed
• Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants ↗

  Nature Genetics · 2007 · PMID 17952073
  not yet assessed
• Genome–wide association studies provide new insights into type 2 diabetes aetiology ↗

  Nature Reviews Genetics · 2007 · PMID 17703236
  not yet assessed
• A common variant of HMGA2 is associated with adult and childhood height in the general population ↗

  Nature Genetics · 2007 · PMID 17767157
  not yet assessed
• Common variants in WFS1 confer risk of type 2 diabetes ↗

  Nature Genetics · 2007 · PMID 17603484
  not yet assessed
• Common Variants of the Novel Type 2 Diabetes Genes<i>CDKAL1</i>and<i>HHEX/IDE</i>Are Associated With Decreased Pancreatic β-Cell Function ↗

  Diabetes · 2007 · PMID 17804762
  not yet assessed
• Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes ↗

  Diabetes · 2007 · PMID 17327436
  not yet assessed
• A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects ↗

  Genes and Immunity · 2007 · PMID 17671508
  not yet assessed
• Type 2 Diabetes TCF7L2 Risk Genotypes Alter Birth Weight: A Study of 24,053 Individuals ↗

  The American Journal of Human Genetics · 2007 · PMID 17503332
  not yet assessed
• Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels ↗

  Genes and Immunity · 2007 · PMID 17443229
  not yet assessed
• A common variant of the p16INK4a genetic region is associated with physical function in older people ↗

  Mechanisms of Ageing and Development · 2007 · PMID 17459456
  not yet assessed
• An Interleukin-18 Polymorphism Is Associated With Reduced Serum Concentrations and Better Physical Functioning in Older People ↗

  The Journals of Gerontology Series A · 2007 · PMID 17301041
  not yet assessed
• The transcription factor 7‐like 2 (<i>TCF7L2</i>) gene is associated with Type 2 diabetes in UK community‐based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies ↗

  Diabetic Medicine · 2007 · PMID 17725629
  not yet assessed
• Genetic studies of diabetes following the advent of the genome-wide association study: where do we go from here? ↗

  Diabetologia · 2007 · PMID 17909877
  not yet assessed
• Genetic Variation and Human Aging: Progress and Prospects ↗

  The Journals of Gerontology Series A · 2007 · PMID 17389728
  not yet assessed
• Common Variation in the <i>LMNA</i> Gene (Encoding Lamin A/C) and Type 2 Diabetes ↗

  Diabetes · 2007 · PMID 17327460
  not yet assessed
• A new era in finding Type 2 diabetes genes—the unusual suspects ↗

  Diabetic Medicine · 2007 · PMID 17561964
  not yet assessed
• Insights on pathogenesis of type 2 diabetes from MODY genetics ↗

  Current Diabetes Reports · 2007 · PMID 17425917
  not yet assessed
• Common variation in the FTO (fused toes) gene is strongly associated with adiposity measures in the northern finnish birth cohort of 1966 ↗

  Diabetologia · 2007
  not yet assessed
• Commentary: Genetic association studies see light at the end of the tunnel ↗

  International Journal of Epidemiology · 2007 · PMID 17921192
  not yet assessed
• A common variant in the FTO gene region is associated with BMI in the general population and predisposes to adult and childhood obesity

  Oxford University Research Archive (ORA) (University of Oxford) · 2007
  not yet assessed
• Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

  Figshare · 2007
  not yet assessed
• Large-scale replication typing of modest signals from genome-wide association studies identifies additional type 2 diabetes susceptibility variants in the IGF2BP2 and VEGFA genes

  Oxford University Research Archive (ORA) (University of Oxford) · 2007
  not yet assessed
• Biological pathway analysis for type 2 diabetes using genome-wide association data

  Oxford University Research Archive (ORA) (University of Oxford) · 2007
  not yet assessed
• Genome-wide association data highlight an aetiological role for disturbances in cyclin-dependent kinase pathways in type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2007
  not yet assessed
• Genome-wide search for multiple loci in type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2007
  not yet assessed
• Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population ↗

  Diabetologia · 2006 · PMID 17093941
  not yet assessed
• Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction ↗

  PLoS Medicine · 2006 · PMID 17020404
  not yet assessed
• Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms <i>TCF7L2</i> as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk ↗

  Diabetes · 2006 · PMID 16936215
  not yet assessed
• A Common Haplotype of the Glucokinase Gene Alters Fasting Glucose and Birth Weight: Association in Six Studies and Population-Genetics Analyses ↗

  The American Journal of Human Genetics · 2006 · PMID 17186458
  not yet assessed
• Effects of the diabetes linked TCF7L2polymorphism in a representative older population ↗

  BMC Medicine · 2006 · PMID 17181866
  not yet assessed
• Triglyceride associated polymorphisms of the APOA5gene have very different allele frequencies in Pune, India compared to Europeans ↗

  BMC Medical Genetics · 2006 · PMID 17032446
  not yet assessed
• No Evidence of Association of <i>ENPP1</i> Variants With Type 2 Diabetes or Obesity in a Study of 8,089 U.K. Caucasians ↗

  Diabetes · 2006 · PMID 17065358
  not yet assessed
• Asian MODY: are we missing an important diagnosis? ↗

  Diabetic Medicine · 2006 · PMID 17054605
  not yet assessed
• The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians ↗

  BMC Medical Genetics · 2006 · PMID 16753056
  not yet assessed
• Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T&gt;C polymorphism of the Apolipoprotein AV gene ↗

  Lipids in Health and Disease · 2006 · PMID 16670016
  not yet assessed
• Epistasis Between Type 2 Diabetes Susceptibility Loci on Chromosomes 1q21‐25 and 10q23‐26 in Northern Europeans ↗

  Annals of Human Genetics · 2006 · PMID 17044847
  not yet assessed
• Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population ↗

  Diabetologia · 2006 · PMID 16601972
  not yet assessed
• Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population. ↗

  PubMed · 2006 · PMID 16685110
  not yet assessed
• Assessment of the Role of Common Genetic Variation in the Transient Neonatal Diabetes Mellitus (TNDM) Region in Type 2 Diabetes ↗

  Diabetes · 2006 · PMID 16873690
  not yet assessed
• The Impact of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on Severe Hypoglycemia in Type 2 Diabetes ↗

  The Review of Diabetic Studies · 2006 · PMID 17487330
  not yet assessed
• Chapter 1 Transcription factor genes in type 2 diabetes ↗

  Advances in molecular and cellular endocrinology · 2006
  not yet assessed
• Large scale case-control and family-based analyses of TCF7L2 variants in > 6000 UK subjects demonstrates an almost two-fold difference in relative risk between homozygote classes

  Diabetologia · 2006
  not yet assessed
• A study of association between common variation in the growth hormone-chorionic somatomammotropin hormone gene cluster and adult fasting insulin in a UK Caucasian population ↗

  Journal of Negative Results in BioMedicine · 2006 · PMID 17125497
  not yet assessed
• Erratum: Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. (Diabetes (2006) 55 (2640-2644))

  Diabetes · 2006
  not yet assessed
• Common variation in the LMNA gene increases susceptibility to type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2006
  not yet assessed
• Association of the calpain-10 gene with type 2 diabetes in Europeans: Results of pooled and meta-analyses.

  HAL (Le Centre pour la Communication Scientifique Directe) · 2006
  not yet assessed
• Genetic Regulation of Birth Weight and Fasting Glucose by a Common Polymorphism in the Islet Cell Promoter of the Glucokinase Gene ↗

  Diabetes · 2005 · PMID 15677518
  not yet assessed
• Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes ↗

  Diabetologia · 2005 · PMID 16132956
  not yet assessed
• A Large-Scale Association Analysis of Common Variation of the <i>HNF1</i>α Gene With Type 2 Diabetes in the U.K. Caucasian Population ↗

  Diabetes · 2005 · PMID 16046319
  not yet assessed
• Examining the relationships between the Pro12Ala variant in <i>PPARG</i> and Type 2 diabetes‐related traits in UK samples ↗

  Diabetic Medicine · 2005 · PMID 16401314
  not yet assessed
• Familial diabetes in Asian families; remember MODY

  2005
  not yet assessed
• Recent Progress in the Identification of Genes Predisposing to the Metabolic Syndrome ↗

  2005
  not yet assessed
• Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes ↗

  New England Journal of Medicine · 2004 · PMID 15115830
  not yet assessed
• 40th EASD Annual Meeting of the European Association for the Study of Diabetes ↗

  Diabetologia · 2004 · PMID 27770180
  not yet assessed
• Common Variants of the Hepatocyte Nuclear Factor-4α P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population ↗

  Diabetes · 2004 · PMID 15504983
  not yet assessed
• Lack of Support for a Role of the Insulin Gene Variable Number of Tandem Repeats Minisatellite (<i>INS</i>-VNTR) Locus in Fetal Growth or Type 2 Diabetes-Related Intermediate Traits in United Kingdom Populations ↗

  The Journal of Clinical Endocrinology & Metabolism · 2004 · PMID 14715866
  not yet assessed
• Association Studies of Insulin Receptor Substrate 1 Gene (<i>IRS1</i>) Variants in Type 2 Diabetes Samples Enriched for Family History and Early Age of Onset ↗

  Diabetes · 2004 · PMID 15561966
  not yet assessed
• Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism ↗

  Diabetologia · 2004 · PMID 15662557
  not yet assessed
• Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the <i>MODY3/NIDDM2</i> Locus on 12q24 ↗

  Diabetes · 2004 · PMID 14988275
  not yet assessed
• Role of the D76N polymorphism of insulin promoter factor-1 in predisposing to Type 2 diabetes ↗

  Diabetologia · 2004 · PMID 15170499
  not yet assessed
• Large-scale association studies of candidate genes and their interactions in Type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2004
  not yet assessed
• Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (<i>KCNJ11</i>) and SUR1 (<i>ABCC8</i>) Confirm That the <i>KCNJ11</i> E23K Variant Is Associated With Type 2 Diabetes ↗

  Diabetes · 2003 · PMID 12540637
  not yet assessed
• Meta-Analysis and a Large Association Study Confirm a Role for Calpain-10 Variation in Type 2 Diabetes Susceptibility ↗

  The American Journal of Human Genetics · 2003 · PMID 14574648
  not yet assessed
• Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility ↗

  Diabetes · 2003 · PMID 12716770
  not yet assessed
• A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young ↗

  Diabetes · 2003 · PMID 12606533
  not yet assessed
• Genetic Variation in the Small Heterodimer Partner Gene and Young-Onset Type 2 Diabetes, Obesity, and Birth Weight in U.K. Subjects ↗

  Diabetes · 2003 · PMID 12716764
  not yet assessed
• Young-Onset Type 2 Diabetes Families Are the Major Contributors to Genetic Loci in the Diabetes UK Warren 2 Genome Scan and Identify Putative Novel Loci on Chromosomes 8q21, 21q22, and 22q11 ↗

  Diabetes · 2003 · PMID 12829657
  not yet assessed
• Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy. ↗

  Lipids in Health and Disease · 2003 · PMID 14613578
  not yet assessed
• In silico searching of human and mouse genome data identifies known and unknown HNF1 binding sites upstream of β-cell genes ↗

  Molecular Genetics and Metabolism · 2003 · PMID 12618086
  not yet assessed
• Variants in the aromatase gene and on the Y‐chromosome are not associated with adult height or insulin resistance in a UK population ↗

  Clinical Endocrinology · 2003 · PMID 12864794
  not yet assessed
• Quantitative traits associated with the Type 2 diabetes susceptibility allele in Kir6.2 ↗

  Diabetologia · 2003 · PMID 12819904
  not yet assessed
• Combining genome and mouse knockout expression data to highlight binding sites for the transcription factor HNF1alpha. ↗

  PubMed · 2003 · PMID 12762846
  not yet assessed
• Combining Genome and Mouse Knockout Expression Data to Highlight Binding Sites for the Transcription Factor HNF1α ↗

  In Silico Biology · 2003
  not yet assessed
• Tall stories: the fundamental difficulties of genetic association studies ↗

  Clinical Endocrinology · 2003 · PMID 14678302
  not yet assessed
• Genes and growth and endocrine diseases

  2003
  not yet assessed
• A Putative Functional Polymorphism in the <i>IGF-I</i> Gene ↗

  Diabetes · 2002 · PMID 12086966
  not yet assessed
• Intrauterine Hyperglycemia Is Associated With an Earlier Diagnosis of Diabetes in HNF-1α Gene Mutation Carriers ↗

  Diabetes Care · 2002 · PMID 12453975
  not yet assessed
• Association Studies of Genetic Variation in the <i>WFS1</i> Gene and Type 2 Diabetes in U.K. Populations ↗

  Diabetes · 2002 · PMID 11916957
  not yet assessed
• Variation in the Calpain-10 Gene Affects Blood Glucose Levels in the British Population ↗

  Diabetes · 2002 · PMID 11756349
  not yet assessed
• Variation within the Type 2 Diabetes Susceptibility Gene Calpain-10 and Polycystic Ovary Syndrome ↗

  The Journal of Clinical Endocrinology & Metabolism · 2002 · PMID 12050223
  not yet assessed
• The role of transcription factors in maturity-onset diabetes of the young ↗

  Molecular Genetics and Metabolism · 2002 · PMID 12359128
  not yet assessed
• Human calcium/calmodulin-dependent protein kinase II gamma gene (CAMK2G): cloning, genomic structure and detection of variants in subjects with Type II diabetes ↗

  Diabetologia · 2002 · PMID 12032636
  not yet assessed
• The role of the HNF4α enhancer in type 2 diabetes ↗

  Molecular Genetics and Metabolism · 2002 · PMID 12083813
  not yet assessed
• Evidence for Linkage of Stature to Chromosome 3p26 in a Large U.K. Family Data Set Ascertained for Type 2 Diabetes ↗

  The American Journal of Human Genetics · 2002 · PMID 11753821
  not yet assessed
• Association of the calpain-10 gene with microvascular function ↗

  Diabetologia · 2002 · PMID 12107735
  not yet assessed
• Rare variants identified in the HNF-4α β-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes ↗

  Diabetologia · 2002 · PMID 12242469
  not yet assessed
• Conflicting results on variation in the IGFI gene highlight methodological considerations in the design of genetic association studies ↗

  Diabetologia · 2002 · PMID 12498159
  not yet assessed
• A Genomewide Scan for Loci Predisposing to Type 2 Diabetes in a U.K. Population (The Diabetes UK Warren 2 Repository): Analysis of 573 Pedigrees Provides Independent Replication of a Susceptibility Locus on Chromosome 1q ↗

  The American Journal of Human Genetics · 2001 · PMID 11484155
  not yet assessed
• Studies of Association between the Gene for Calpain-10 and Type 2 Diabetes Mellitus in the United Kingdom ↗

  The American Journal of Human Genetics · 2001 · PMID 11481585
  not yet assessed
• The role of genetic susceptibility in the association of low birth weight with type 2 diabetes ↗

  British Medical Bulletin · 2001 · PMID 11809620
  not yet assessed
• beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors. ↗

  Diabetes · 2001 · PMID 11272211
  not yet assessed
• beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations. ↗

  Diabetes · 2001 · PMID 11272165
  not yet assessed
• Clinical Consequences of Defects in β-Cell Genes ↗

  Endocrine updates · 2001
  not yet assessed
• A genome scan reveals heterogeneity among European families with maturity onset diabetes of the young

  Oxford University Research Archive (ORA) (University of Oxford) · 2001
  not yet assessed
• Calcium/calmodulin dependent protein kinase II genes: Genomic structure and screening for variants in subjects with Type 2 diabetes

  Oxford University Research Archive (ORA) (University of Oxford) · 2001
  not yet assessed
• beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations.

  HAL (Le Centre pour la Communication Scientifique Directe) · 2001
  not yet assessed
• Mutations in the human Delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis ↗

  Nature Genetics · 2000 · PMID 10742114
  not yet assessed
• Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1β1 ↗

  Kidney International · 2000 · PMID 10720943
  not yet assessed
• Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles. ↗

  Diabetes · 2000 · PMID 10615960
  not yet assessed
• Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin ↗

  Diabetologia · 2000 · PMID 11151767
  not yet assessed
• Confirmation of linkage of Duane's syndrome and refinement of the disease locus to an 8.8-cM interval on chromosome 2q31 ↗

  Human Genetics · 2000 · PMID 10942112
  not yet assessed
• Confirmation of linkage of Duane's syndrome and refinement of the disease locus to an 8.8-cM interval on chromosome 2q31 ↗

  Human Genetics · 2000
  not yet assessed
• No Evidence for Linkage at Candidate Type 2 Diabetes Susceptibility Loci on Chromosomes 12 and 20 in United Kingdom Caucasians ↗

  The Journal of Clinical Endocrinology & Metabolism · 2000 · PMID 10690901
  not yet assessed
• Proposed mechanism for a novel insertion/deletion frameshift mutation (I414G415ATCG?CCA) in the hepatocyte nuclear factor 1 alpha (HNF-1?) gene which causes maturity-onset diabetes of the young (MODY) ↗

  Human Mutation · 2000 · PMID 10980542
  not yet assessed
• No Evidence for Linkage at Candidate Type 2 Diabetes Susceptibility Loci on Chromosomes 12 and 20 in United Kingdom Caucasians ↗

  The Journal of Clinical Endocrinology & Metabolism · 2000
  not yet assessed
• Maternally inherited diabetes and deafness (MIDD) syndrome is associated with poor fetal outcome and a reduced post-natal growth ↗

  Diabetes Research and Clinical Practice · 2000
  not yet assessed
• The BDA Warren Type 2 Diabetes Sibpair Repository: Susceptibility regions identified by genome scan of 439 European families

  Oxford University Research Archive (ORA) (University of Oxford) · 2000
  not yet assessed
• Proposed mechanism for a novel insertion/deletion frameshift mutation (I414G415ATCG→CCA) in the hepatocyte nuclear factor 1 alpha (HNF-1α) gene which causes maturity-onset diabetes of the young (MODY) Communicated by: R.G.H. Cotton Online Citation: Human Mutation, Mutation in Brief #360 (2000) Online http://journals.wiley.com/1059-7794/pdf/mutation/360.pdf ↗

  Human Mutation · 2000
  not yet assessed
• Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes ↗

  Journal of Clinical Investigation · 1999 · PMID 10545530
  not yet assessed
• 35th Annual Meeting of the European Association for the Study of Diabetes ↗

  Diabetologia · 1999 · PMID 10505080
  not yet assessed
• A Gene for Autosomal Recessive Spondylocostal Dysostosis Maps to 19q13.1-q13.3 ↗

  The American Journal of Human Genetics · 1999 · PMID 10364530
  not yet assessed
• Allelic drop-out in exon 2 of the hepatocyte nuclear factor-1alpha gene hinders the identification of mutations in three families with maturity-onset diabetes of the young. ↗

  Diabetes · 1999 · PMID 10102714
  not yet assessed
• Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes. ↗

  Diabetes · 1999 · PMID 10580439
  not yet assessed
• Beta-cell genes in the pathogenesis of type 2 diabetes.

  OpenGrey (Institut de l'Information Scientifique et Technique) · 1999
  not yet assessed
• Type 2 diabetes and the human homolog of the rat insulin resistance gene, CD36: No linkage or association in Europeans

  Oxford University Research Archive (ORA) (University of Oxford) · 1999
  not yet assessed
• Mutations in hepatocyte nuclear factor 1beta are not a common cause of maturity-onset diabetes of the young in the U.K. ↗

  Diabetes · 1998
  not yet assessed
• C282Y mutation in HFE (haemochromatosis) gene and type 2 diabetes ↗

  The Lancet · 1998 · PMID 9654270
  not yet assessed
• Haemochromatosis and type 2 diabetes ↗

  The Lancet · 1998
  not yet assessed
• Mutations in the Hepatocyte Nuclear Factor–1α Gene Are a Common Cause of Maturity-Onset Diabetes of the Young in the U.K. ↗

  Diabetes · 1997 · PMID 9075818
  not yet assessed
• Mutations in the hepatocyte nuclear factor-1alpha gene are a common cause of maturity-onset diabetes of the young in the U.K ↗

  Diabetes · 1997
  not yet assessed
• A missense mutation in the hepatocyte nuclear factor 4 alpha gene in a UK pedigree with maturity-onset diabetes of the young ↗

  Diabetologia · 1997 · PMID 9243109
  not yet assessed
• A rapid screening method for hepatocyte nuclear factor 1 alpha frameshift mutations; prevalence in maturity-onset diabetes of the young and late-onset non-insulin dependent diabetes ↗

  Human Genetics · 1997 · PMID 9439666
  not yet assessed