Dario F. De Jesus
Reproducibility track record
1
assessed papers
10/100
mean reproducibility
0
reproduced (C1–C2)
1
flagged
100
total citations
flag rate:
100%
(1/1)
The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.
Authorship role
first author: 0
last author: 0
Topics
Funders
—
Frequent co-authors
Agnieszka Chryplewicz 1Ernst Lengyel 1Mark A. Eckert 1Allen Zhu 1Rohit Kulkarni 1Decheng Ren 1Chuan He 1Qi Zhang 1Zijie Zhang 1Mengjie Chen 1
Institutions
Howard Hughes Medical Institute 1University of Chicago 1Joslin Diabetes Center 1Harvard University 1
Geography (author institutions)
US 1
Co-author network
Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.
How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.
Assessed papers (1)
Complete publication record (69)
Request a reproduction →1 assessed by us (0 reproduced) · 68 not yet assessed — every PubMed paper on record, linked below.
-
Pancreatic β-cell aging in physiology and diabetes: emerging roles of m6A mRNA methylation ↗Journal of Molecular Endocrinology · 2026 · PMID 42274290not yet assessed
-
m6A mRNA methylation regulates pancreatic α-cell plasticity ↗Nature Metabolism · 2026not yet assessed
-
Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism ↗Nature Communications · 2025 · PMID 39788955not yet assessed
-
Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival ↗Nature Communications · 2025 · PMID 41093834not yet assessed
-
Regulatory Roles of IGF2R in Insulin Secretion and Adaptive β-Cell Proliferation ↗Diabetes · 2025 · PMID 41042627not yet assessed
-
m 6 A mRNA methylation decorates genes involved in fibrinogen synthesis to regulate liver regeneration in mice ↗American Journal of Physiology-Gastrointestinal and Liver Physiology · 2025 · PMID 41056353not yet assessed
-
not yet assessed
-
1614-P: Comprehensive Epitranscriptomic Analysis Reveals Novel Glucose-Responsive and Reversible Pathways in Mouse Liver ↗Diabetes · 2025not yet assessed
-
79-OR: SEC31A: A Novel Regulator of Pancreatic Alpha-Cell Survival Identified via Genome-Wide CRISPR Screen ↗Diabetes · 2025not yet assessed
-
not yet assessed
-
195-OR: The Ubiquitin-Ligase Substrate Adaptor KCTD17 Controls β-Cell Compensation to Insulin Resistance in Type 2 Diabetes ↗Diabetes · 2025not yet assessed
-
not yet assessed
-
not yet assessed
-
not yet assessed
-
Author Correction: Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes ↗Nature Cell Biology · 2025 · PMID 41249573not yet assessed
-
Corrigendum to “Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation” [Mol Metab 18 (2018) 153–163] ↗Molecular Metabolism · 2025 · PMID 41285400not yet assessed
-
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes ↗Nature Cell Biology · 2024 · PMID 38409327not yet assessed
-
SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes ↗Journal of Clinical Investigation · 2024 · PMID 38713514not yet assessed
-
m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1 ↗Cell Metabolism · 2024 · PMID 39255799not yet assessed
-
m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation ↗The EMBO Journal · 2024 · PMID 39322760not yet assessed
-
362-OR: Divergent Roles of METTL14-Mediated m6A in Regulating Brown and White Adipose Tissue Transcriptomes and Systemic Metabolism ↗Diabetes · 2024not yet assessed
-
7624 m6A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis ↗Journal of the Endocrine Society · 2024not yet assessed
-
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways ↗Cell Metabolism · 2023 · PMID 37339634not yet assessed
-
NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes ↗Cell chemical biology · 2023 · PMID 37354909not yet assessed
-
Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia ↗Journal of Biological Chemistry · 2023 · PMID 37392854not yet assessed
-
234-OR: Succinate Potentiates Insulin Secretion through SUCNR1 ↗Diabetes · 2023not yet assessed
-
Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses ↗eLife · 2023 · PMID 37732504not yet assessed
-
Redox Regulation of m 6 A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 36824909not yet assessed
-
m 6 A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37292780not yet assessed
-
m 6 A mRNA Methylation Regulates Early Pancreatic β-Cell Differentiation ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37577492not yet assessed
-
363-OR: Brown Adipose Tissue m6A mRNA Methylation Regulates Systemic Insulin Sensitivity via a Prostaglandin Interorgan Axis ↗Diabetes · 2023not yet assessed
-
83-OR: Defining the Transcriptome and Epitranscriptome of the ß-Cell Compensation to Insulin Resistance ↗Diabetes · 2023not yet assessed
-
198-OR: Pancreatic Elastase Regulates Human Beta-Cell Viability by Impairing the PAR2 Pathway ↗Diabetes · 2023not yet assessed
-
When Losing Weight Causes Type-2 Diabetes ↗Zenodo (CERN European Organization for Nuclear Research) · 2023not yet assessed
-
not yet assessed
-
Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b ↗Science Translational Medicine · 2022 · PMID 35320000not yet assessed
-
E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance ↗Cell Reports · 2022 · PMID 36198264not yet assessed
-
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice ↗Nature Communications · 2022 · PMID 36443308not yet assessed
-
247-LB: Pancreatic Elastase Regulates ß-Cell Viability by Impairing the Mechanosignaling Pathway ↗Diabetes · 2022not yet assessed
-
9-OR: ADA Presidents' Select Abstract: m6A mRNA Methylation Regulates the Innate Immune Response in Human Beta Cells ↗Diabetes · 2022not yet assessed
-
Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
-
287-OR: M6A mRNA Methylation Regulates the Innate Immune Response in Human ß-Cells ↗Diabetes · 2021not yet assessed
-
scEMC10, a novel circulating inhibitor of adipocyte thermogenesis, is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity ↗Research Square · 2021not yet assessed
-
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice ↗Journal of Clinical Investigation · 2020 · PMID 32250344not yet assessed
-
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism ↗Nature Communications · 2020 · PMID 32005828not yet assessed
-
Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway ↗Diabetologia · 2020 · PMID 31897526not yet assessed
-
More is better: combinatorial therapy to restore β-cell function in diabetes ↗Nature Metabolism · 2020 · PMID 32694691not yet assessed
-
1811-P: Induction of Hepatic Steatosis by a Methionine Choline Deficient Diet Promotes FGF21-Induced Insulin Secretion Independent of Diabetes ↗Diabetes · 2020not yet assessed
-
m6A mRNA methylation regulates human β-cell biology in physiological states and in type 2 diabetes ↗Nature Metabolism · 2019 · PMID 31867565not yet assessed
-
RADAR: differential analysis of MeRIP-seq data with a random effect model⚑Genome biology · 2019 · PMID 31870409L1 10/100 ⚑
-
Human duct cells contribute to β cell compensation in insulin resistance ↗JCI Insight · 2019 · PMID 30996131not yet assessed
-
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes ↗Nature Metabolism · 2019 · PMID 31423480not yet assessed
-
“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance ↗Molecular Metabolism · 2019 · PMID 31500830not yet assessed
-
Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes ↗Diabetes · 2019 · PMID 30833467not yet assessed
-
1874-P: A Novel Role for SerpinB1 in the Regulation of Insulin Signaling in Hepatocytes ↗Diabetes · 2019not yet assessed
-
RADAR: Differential analysis of MeRIP-seq data with a random effect model ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
-
Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation ↗Molecular Metabolism · 2018 · PMID 30316806not yet assessed
-
Beta-Cell SCHAD Deficiency Causes Hypoglycemia in Mice ↗Diabetes · 2018not yet assessed
-
not yet assessed
-
Insulin Receptor–Mediated Signaling Regulates Pluripotency Markers and Lineage Differentiation ↗Diabetes · 2018not yet assessed
-
NREP Bridges TGF-ß Signaling and Lipid Metabolism in the Epigenetic Reprogramming of NAFLD in the Offspring of Insulin-Resistant Parents ↗Diabetes · 2018not yet assessed
-
Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass ↗European Journal of Clinical Nutrition · 2017 · PMID 28294170not yet assessed
-
SerpinB1 Promotes Pancreatic β Cell Proliferation ↗Cell Metabolism · 2015 · PMID 26701651not yet assessed
-
Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics ↗Journal of Proteome Research · 2015 · PMID 26151086not yet assessed
-
Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts ↗Stem Cells Translational Medicine · 2015 · PMID 26253715not yet assessed
-
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring ↗American Journal of Physiology-Endocrinology and Metabolism · 2014 · PMID 25249504not yet assessed
-
Epigenetic modifiers of islet function and mass ↗Trends in Endocrinology and Metabolism · 2014 · PMID 25246382not yet assessed
-
Soluble Factors Secreted by T Cells Promote β-Cell Proliferation ↗Diabetes · 2013 · PMID 24089508not yet assessed
-
Soluble factors secreted by Tcells promote βcell proliferation2013not yet assessed
Full bibliography from OpenAlex; reproducibility verdicts matched by PMID.
Author attribution follows OpenAlex disambiguation, which is imperfect — a researcher's papers can be split across profiles or mixed with a namesake.
Merged across profiles sharing this ORCID where present. See every “Jesus D” paper on PubMed ↗