Sasikanth Manne

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

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How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• Vaccine-induced ICOS<sup>+</sup>CD38<sup>+</sup> circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathway
  2021 L1 88/100

1 assessed by us (1 reproduced) · 108 not yet assessed — every PubMed paper on record, linked below.

• Publisher Correction: Tissue-resident exhausted and memory CD8+ T cells have distinct ontogeny, function and roles in disease ↗

  Nature Immunology · 2026 · PMID 41530425
  not yet assessed
• Precision CRISPR annotation of the functional enhancer landscape in primary human T cells ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2026 · PMID 41659577
  not yet assessed
• Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate ↗

  Science Immunology · 2025 · PMID 40053604
  not yet assessed
• Tissue-resident exhausted and memory CD8+ T cells have distinct ontogeny, function and roles in disease ↗

  Nature Immunology · 2025 · PMID 41461986
  not yet assessed
• Deciphering the role of histone modifications in memory and exhausted CD8 T cells ↗

  Scientific Reports · 2025 · PMID 40389726
  not yet assessed
• Optimal pairing of binder and co-stimulatory domains improves dual CART cell efficacy ↗

  Molecular Therapy · 2025 · PMID 40770877
  not yet assessed
• Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8 ⁺ T cells underlies distinct functional potential ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 40832341
  not yet assessed
• Deciphering the role of histone modifications in memory and exhausted CD8 T cells ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• Divergent ontogeny of tissue resident memory and tissue resident exhausted CD8 T cells underlies distinct functional potential 4588 ↗

  The Journal of Immunology · 2025
  not yet assessed
• Tumor-specific stem-like progenitor exhausted CD8+ T cell subsets diverge into terminally exhausted cells and long-lived memory T cells 3102 ↗

  The Journal of Immunology · 2025
  not yet assessed
• LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity ↗

  Cell · 2024 · PMID 39121848
  not yet assessed
• Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells ↗

  Cancer Cell · 2024 · PMID 39214097
  not yet assessed
• LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity ↗

  Cell · 2024 · PMID 39121847
  not yet assessed
• Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment ↗

  Nature Immunology · 2024 · PMID 38267693
  not yet assessed
• Characteristics and outcomes of hospitalised adults with COVID-19 in a Global Health Research Network: A cohort study ↗

  UNC Libraries · 2024
  not yet assessed
• Fate mapping LAG3+ exhausted CD8+ T cells. ↗

  The Journal of Immunology · 2024
  not yet assessed
• Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure ↗

  Immunity · 2023 · PMID 38091951
  not yet assessed
• In vitro modeling of CD8 ⁺ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40 ↗

  Science Immunology · 2023 · PMID 37595022
  not yet assessed
• The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells ↗

  Immunity · 2023 · PMID 37315535
  not yet assessed
• Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment ↗

  Nature Immunology · 2023 · PMID 37845489
  not yet assessed
• <i>In Vitro</i> Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40 ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37131713
  not yet assessed
• Reinvigoration of Progenitor-Exhausted CD8 T Cells by anti-CTLA-4 Contributes to the Sustained Activity of Combination Checkpoint Blockade ↗

  SSRN Electronic Journal · 2023
  not yet assessed
• Supplementary Figures 1 - 5 from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Supplementary Materials and Methods from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Supplementary Figure Legends from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Supplementary Figures 1 - 5 from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Supplementary Materials and Methods from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Supplementary Figure Legends from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Supplementary Figure, Figure Legends, Tables and Material and Methods from The Codon 72 &lt;i&gt;TP53&lt;/i&gt; Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis ↗

  2023
  not yet assessed
• Supplementary Figure, Figure Legends, Tables and Material and Methods from The Codon 72 &lt;i&gt;TP53&lt;/i&gt; Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis ↗

  2023
  not yet assessed
• Data from The Codon 72 &lt;i&gt;TP53&lt;/i&gt; Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis ↗

  2023
  not yet assessed
• Tri-modal single cell (TEA-seq) profiling reveals a novel, epigenetically distinct T cell subset in children and global molecular reprogramming across age ↗

  The Journal of Immunology · 2023
  not yet assessed
• 579-C Reinvigoration of progenitor-exhausted CD8 T cells by anti-CTLA-4 contributes to the sustained activity of combination checkpoint blockade ↗

  2023
  not yet assessed
• 1016 Enforcement of exhausted T cell epigenetic fate by HMG-box transcription factor TOX ↗

  Regular and Young Investigator Award Abstracts · 2023
  not yet assessed
• Data from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Data from Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  2023
  not yet assessed
• Data from The Codon 72 &lt;i&gt;TP53&lt;/i&gt; Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis ↗

  2023
  not yet assessed
• Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics ↗

  Nature Immunology · 2022 · PMID 36271148
  not yet assessed
• Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers ↗

  Immunity · 2022 · PMID 35263570
  not yet assessed
• Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3 ↗

  Nature Immunology · 2022 · PMID 35618829
  not yet assessed
• PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine ↗

  Nature Immunology · 2022 · PMID 35902637
  not yet assessed
• Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19 ↗

  Frontiers in Immunology · 2022 · PMID 35309299
  not yet assessed
• MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection ↗

  Proceedings of the National Academy of Sciences · 2022 · PMID 35446623
  not yet assessed
• Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Longitudinal single cell transcriptional and epigenetic mapping of effector, memory, and exhausted CD8 T cells reveals shared biological circuits across distinct cell fates ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Abstract 3579: T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade ↗

  Cancer Research · 2022
  not yet assessed
• PD-1 restricts the development and effector function of tissue regulatory T cells in experimental autoimmune encephalomyelitis ↗

  The Journal of Immunology · 2022
  not yet assessed
• Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation ↗

  Nature Immunology · 2021 · PMID 34312545
  not yet assessed
• In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer ↗

  Cell · 2021 · PMID 33636129
  not yet assessed
• Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells ↗

  Cell Reports · 2021 · PMID 33979613
  not yet assessed
• Inhibitory signaling sustains a distinct early memory CD8 ⁺ T cell precursor that is resistant to DNA damage ↗

  Science Immunology · 2021 · PMID 33452106
  not yet assessed
• Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways

  Cell Reports Medicine · 2021 · PMID 34095875
  L1 88/100
• Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19 ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2021 · PMID 33972943
  not yet assessed
• Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation ↗

  Nature Immunology · 2021 · PMID 34588688
  not yet assessed
• TET2 controls differentiation of terminally exhausted CD8 T cells ↗

  The Journal of Immunology · 2021
  not yet assessed
• Abstract PO068: Distinct immune signatures predicting clinical response to PD-1 blockade therapy in gynecological cancers revealed by high-dimensional immune profiling ↗

  Cancer Immunology Research · 2021
  not yet assessed
• 253 PD1 and LAG3 converge to limit polyfunctionality and systemic immunity ↗

  Regular and Young Investigator Award Abstracts · 2021
  not yet assessed
• 310 T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade ↗

  Regular and Young Investigator Award Abstracts · 2021
  not yet assessed
• A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion ↗

  The Journal of Immunology · 2021
  not yet assessed
• Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications ↗

  Science · 2020 · PMID 32669297
  not yet assessed
• Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms ↗

  Immunity · 2020 · PMID 32396847
  not yet assessed
• Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity ↗

  Nature Immunology · 2020 · PMID 32661362
  not yet assessed
• The Identity of Human Tissue-Emigrant CD8+ T Cells ↗

  Cell · 2020 · PMID 33306960
  not yet assessed
• Therapeutic Targeting of Vasculature in the Premetastatic and Metastatic Niches Reduces Lung Metastasis ↗

  The Journal of Immunology · 2020 · PMID 31900334
  not yet assessed
• Exploration of T-Cell Diversity Using Mass Cytometry ↗

  Methods in molecular biology · 2020 · PMID 31933194
  not yet assessed
• Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020 · PMID 32511371
  not yet assessed
• The identity of human tissue-emigrant CD8 ⁺ T cells ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• <i>In vivo</i> CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Developmental relationships of four exhausted CD8 T cell subsets reveals underlying transcriptional and epigenetic control mechanisms ↗

  The Journal of Immunology · 2020
  not yet assessed
• 186 Distinct immune signatures predicting clinical response to PD-1 blockade therapy in gynecological cancers revealed by high-dimensional immune profiling ↗

  Regular and Young Investigator Award Abstracts · 2020
  not yet assessed
• Targeting TNFR2 to overcome acquired adaptive resistance to immune checkpoint blockade ↗

  The Journal of Immunology · 2020
  not yet assessed
• Mechanisms by which Obesity Dysregulates Immunometabolic State in Asthma ↗

  Journal of Allergy and Clinical Immunology · 2020
  not yet assessed
• Abstract B80: High dimensional DNA damage and repair (DDR) cytometric profiling of human T cell subsets revealed distinct DDR signatures ↗

  Cancer Immunology Research · 2020
  not yet assessed
• Abstract IA04: Overcoming immune resistance with rationally designed combination immunotherapy ↗

  Cancer Research · 2020
  not yet assessed
• &lt;i&gt;In vivo&lt;/i&gt;&amp;nbsp;CRISPR Screening Identifies Fli1 as a Transcriptional Safeguard that Restrains Effector CD8 T Cell Differentiation During Infection and Cancer ↗

  SSRN Electronic Journal · 2020
  not yet assessed
• T cell exhaustion dynamics are linked to clinical outcomes in hepatocellular carcinoma ↗

  Journal of Hepatology · 2020
  not yet assessed
• T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade ↗

  The Journal of Immunology · 2020
  not yet assessed
• PD1 and LAG3 converge to limit polyfunctionality and systemic immunity ↗

  The Journal of Immunology · 2020
  not yet assessed
• TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion ↗

  Nature · 2019 · PMID 31207603
  not yet assessed
• TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision ↗

  Immunity · 2019 · PMID 31606264
  not yet assessed
• A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma ↗

  Nature Medicine · 2019 · PMID 30804515
  not yet assessed
• The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs ↗

  Science Translational Medicine · 2019 · PMID 31189717
  not yet assessed
• T follicular helper cells in human efferent lymph retain lymphoid characteristics ↗

  Journal of Clinical Investigation · 2019 · PMID 31264971
  not yet assessed
• The Codon 72 <i>TP53</i> Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis ↗

  Molecular Cancer Research · 2019 · PMID 31088907
  not yet assessed
• Chronic viral infection promotes early germinal center exit of B cells and impaired antibody development ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• Vaccine-induced ICOS+CD38+ cTfh are sensitive biosensors of age-related changes in inflammatory pathways ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• OBESITY DYSREGULATES IMMUNOMETABOLIC STATUS IN ASTHMA AND IMPACTS VACCINE RESPONSES ↗

  Journal of Allergy and Clinical Immunology · 2019
  not yet assessed
• Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells ↗

  Immunity · 2018 · PMID 29768164
  not yet assessed
• Identification and characterization of HIV-specific resident memory CD8 ⁺ T cells in human lymphoid tissue ↗

  Science Immunology · 2018 · PMID 29858286
  not yet assessed
• Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity ↗

  Cancer Cell · 2018 · PMID 29894689
  not yet assessed
• Non-conventional Inhibitory CD4+Foxp3–PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity ↗

  Cancer Cell · 2018 · PMID 30300585
  not yet assessed
• Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155 ↗

  Cell Reports · 2018 · PMID 29768211
  not yet assessed
• Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection ↗

  Cell Reports · 2018 · PMID 29320737
  not yet assessed
• Chronic Allergen Stimulation Yields T cell Dysfunction in Obese Asthmatics ↗

  Journal of Allergy and Clinical Immunology · 2018
  not yet assessed
• Veterinary Considerations for the Theoretical Resurrection of Extinct Species ↗

  Journal of Veterinary Science and Animal Husbandry · 2018
  not yet assessed
• Modulation of TFH-like cells and anti-tumor activity of immune checkpoint blockade. ↗

  The Journal of Immunology · 2018
  not yet assessed
• T-cell invigoration to tumour burden ratio associated with anti-PD-1 response ↗

  Nature · 2017 · PMID 28397821
  not yet assessed
• miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb ↗

  Cell Reports · 2017 · PMID 28903040
  not yet assessed
• Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche ↗

  Immunity · 2017 · PMID 29031786
  not yet assessed
• Notch transactivates Rheb to maintain the multipotency of TSC-null cells ↗

  Nature Communications · 2017 · PMID 29184052
  not yet assessed
• Differentiation and Protective Capacity of Virus-Specific CD8

  The Medicine Forum · 2017
  not yet assessed
• Metabolic and Deep Immune Profiling Reveal Coordinate Effects on Immune Function in Asthma and Obesity ↗

  Journal of Allergy and Clinical Immunology · 2017
  not yet assessed
• Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade ↗

  Science · 2016 · PMID 27789795
  not yet assessed
• MiR-150 negatively regulates CD8+ T cell memory formation ↗

  The Journal of Immunology · 2016
  not yet assessed
• Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex ↗

  Oncogene · 2015 · PMID 26434588
  not yet assessed
• Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche ↗

  Cancer Research · 2014 · PMID 24786787
  not yet assessed
• Complement factor H polymorphism in age-related macular degeneration ↗

  American Journal of Ophthalmology · 2005
  not yet assessed