Expression Project for Oncology (expO)
The mission of expO is to build on the technologies and outcomes of the Human Genome Project to accelerate improved clinical management of cancer patients. IGC's Expression Project for Oncology (expO) seeks to integrate longitudinal clinical annotation with gene expression data for a unique and powerful portrait of human malignancies, providing critical perspective on diagnostic markers, prognostic indicators, and therapeutic targets. The goal of expO and its consortium supporters is to procur...
Provenance — who produced it, who reused it
Linked to 130 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- The consensus molecular subtypes of colorectal cancer 2015 · 5,246 cites
- The splicing factor SRSF1 regulates apoptosis and proliferation... 2012 · 467 cites
- Breast cancer signatures for invasiveness and prognosis defined... 2012 · 363 cites
- LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor... 2019 · 338 cites
- A Three-Gene Model to Robustly Identify Breast Cancer Molecular... 2012 · 328 cites
- TNBCtype: A Subtyping Tool for Triple-Negative Breast Cancer 2012 · 303 cites
- Subtypes of primary colorectal tumors correlate with response to... 2012 · 257 cites
- DeepCC: a novel deep learning-based framework for cancer molecul... 2019 · 234 cites
- Epigenetic expansion of VHL-HIF signal output drives multiorgan... 2012 · 219 cites
- Critical role for lysyl oxidase in mesenchymal stem cell-driven... 2012 · 218 cites
- curatedOvarianData: clinically annotated data for the ovarian ca... 2013 · 213 cites
- Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Ta... 2012 · 202 cites
- Actin stress fiber organization promotes cell stiffening and pro... 2017 · 182 cites
- Chronic acidosis in the tumour microenvironment selects for over... 2015 · 180 cites
- EMT is associated with an epigenetic signature of ECM remodeling... 2019 · 148 cites
- Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate T... 2013 · 148 cites
- Random generalized linear model: a highly accurate and interpret... 2013 · 145 cites
- A palmitate-rich metastatic niche enables metastasis growth via... 2023 · 140 cites
- Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and In... 2013 · 137 cites
- MERAV: a tool for comparing gene expression across human tissues... 2015 · 135 cites
- Prognostic genome and transcriptome signatures in colorectal can... 2024 · 134 cites
- Notch1 counteracts WNT/β-catenin signaling through chromatin mod... 2012 · 133 cites
- A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF... 2016 · 109 cites
- <i>Helicobacter pylori</i> ‐induced miR‐135b‐5p promotes cisplat... 2018 · 109 cites
- Differential Functions of Splicing Factors in Mammary Transforma... 2019 · 102 cites
- Metastasis-suppressor transcript destabilization through TARBP2... 2014 · 101 cites
- TAGLN mediated stiffness-regulated ovarian cancer progression vi... 2021 · 98 cites
- The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to... 2019 · 92 cites
- A distinct p53 target gene set predicts for response to the sele... 2015 · 87 cites
- The cell cycle regulator 14-3-3σ opposes and reverses cancer met... 2015 · 87 cites
- Activation of GATA binding protein 6 ( <i>GATA6</i> ) sustains o... 2012 · 83 cites
- ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal... 2015 · 82 cites
- Relating hepatocellular carcinoma tumor samples and cell lines u... 2015 · 82 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
- The HDL receptor SR-BI is associated with human prostate cancer... 2015 · 79 cites
- Endocrine Fibroblast Growth Factor FGF19 Promotes Prostate Cance... 2013 · 79 cites
- DNA hypomethylation-mediated activation of<i>Cancer/Testis Antig... 2015 · 78 cites
- Molecular portraits and trastuzumab responsiveness of estrogen r... 2019 · 76 cites
- Translating bioinformatics in oncology: guilt-by-profiling analy... 2014 · 75 cites
- CSN6 drives carcinogenesis by positively regulating Myc stabilit... 2014 · 71 cites
40 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.