Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• SEAseq: a portable and cloud-based chromatin occupancy analysis suite.

  PMID 35193506 · PMC8864840 · BMC bioinformatics · 2022 · 7 claims · 2 setups

  Has reproduction · 94

  SEAseq is a comprehensive, infrastructure-independent pipeline that performs the major analyses needed to process ChIP-Seq/CUT&RUN chromatin binding datasets in a single execution

  any chip-seq cut&run

• nf-core/isoseq: simple gene and isoform annotation with PacBio Iso-Seq long-read sequencing.

  PMID 36961337 · PMC10199315 · Bioinformatics (Oxford, England) · 2023 · 7 claims · 4 setups

  Has reproduction · 88

  nf-core/isoseq is a new automated Nextflow-based pipeline that processes raw Iso-Seq subreads through to genome annotation (BED format) without requiring transcriptome assembly.

  organism-specific iso-seq reference mapped pacbio subread long-read

• The genome sequence of the Spanish Fritillary, Euphydryas desfontainii (Godart, 1819) (Lepidoptera: Nymphalidae).

  PMID 41835093 · PMC12988360 · Wellcome open research · 2026 · 7 claims · 8 setups

  Full-text index only

  A chromosome-level genome assembly was produced for Euphydryas desfontainii from a single male specimen, comprising two haplotypes of 755.68 Mb and 751.57 Mb

  organism euphydryas pacbio hi-c k-mer

• Analysis of the genome of the New Zealand giant collembolan (Holacanthella duospinosa) sheds light on hexapod evolution.

  PMID 29041914 · PMC5644144 · BMC genomics · 2017 · 8 claims · 8 setups

  Has reproduction · 72

  Phylogenomic analysis (370,877 amino acids) placed H. duospinosa within the family Neanuridae

  holacanthella duospinosa genome transcriptome phylogenomics

• The genome of the ant Tetramorium bicarinatum reveals a tandem organization of venom peptides genes allowing the prediction of their regulatory and evolutionary profiles.

  PMID 38245722 · PMC10800049 · BMC genomics · 2024 · 8 claims · 8 setups

  Has reproduction · 100

  44 venom peptide genes were identified, distributed across four of the eleven chromosomes and organized in tandem repeat clusters.

  tetramorium bicarinatum vpg venom whole-genome blast gene

• Pathway projector: web-based zoomable pathway browser using KEGG atlas and Google Maps API.

  PMID 19907644 · PMC2770834 · PloS one · 2009 · 8 claims · 6 setups

  Full-text index only

  Existing pathway databases and tools do not satisfy all requirements for a generic, comprehensive pathway browser (integrated maps, data access, mapping/editing, export, installation-free availability).

  kegg 8192x8192 user-submitted species pathway zoomable sequence

• The chromosomal genome sequence of the carnivorous sponge, Lycopodina hypogea (Vacelet & Boury-Esnault, 1996) (Poecilosclerida: Cladorhizidae) and its associated microbial metagenome sequences.

  PMID 41835092 · PMC12988363 · Wellcome open research · 2026 · 7 claims · 7 setups

  Full-text index only

  A chromosome-level genome assembly of Lycopodina hypogea was generated, with total length 235.10 Mb and 98.85% of sequence scaffolded into 15 chromosomal pseudomolecules.

  lycopodina microbial hypogea pacbio hi-c rna-seq

• The genome sequence of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham, 1802) (Coleoptera: Curculionidae).

  PMID 42109707 · PMC13153772 · Wellcome open research · 2026 · 8 claims · 4 setups

  Full-text index only

  A chromosome-level genome assembly for Ceutorhynchus obstrictus was generated with total length 728.81 Mb

  organism dissected pacbio hi-c rna-seq

• The genome sequence of a window fly, Scenopinus jerei Pohjoismäki & Haarto, 2021 (Diptera: Scenopinidae).

  PMID 41953045 · PMC13054250 · Wellcome open research · 2026 · 8 claims · 8 setups

  Full-text index only

  This assembly provides the first genomic resource for the family Scenopinidae (window flies)

  organism idscejere3 assembled pacbio hi-c rna-seq

• Ensembl 2006.

  PMID 16381931 · PMC1347495 · Nucleic acids research · 2006 · 8 claims · 5 setups

  Full-text index only

  Ensembl now provides annotation for 19 genomes, up from 4 the previous year, including new mammalian (Rhesus macaque, Opossum), chordate (Ciona intestinalis), and yeast genomes.

  cow ensembl snps genome gene whole-genome pairwise

• The genome sequence of the Eastern Rock Grayling, Hipparchia syriaca (Staudinger, 1871) (Lepidoptera: Nymphalidae).

  PMID 41913757 · PMC13033134 · Wellcome open research · 2026 · 8 claims · 8 setups

  Full-text index only

  A chromosome-level genome assembly was generated for Hipparchia syriaca (Eastern Rock Grayling) from a female specimen collected in Măcin, Romania

  organism pacbio assembled pacbio hi-c k-mer

• Human Retrotransposons and Effective Computational Detection Methods for Next-Generation Sequencing Data.

  PMID 36295018 · PMC9605557 · Life (Basel, Switzerland) · 2022 · 8 claims · 7 setups

  Has reproduction

  Retrotransposons mobilize via a copy-and-paste mechanism involving transcription of an RNA intermediate and reinsertion as a cDNA copy, unlike DNA transposons which cut-and-paste.

  drosophila normal genomic genome synthetic whole-genome computational

• MEDUSA: A Pipeline for Sensitive Taxonomic Classification and Flexible Functional Annotation of Metagenomic Shotgun Sequences.

  PMID 35330728 · PMC8940201 · Frontiers in genetics · 2022 · 7 claims · 6 setups

  Has reproduction · 50

  MEDUSA correctly identifies more species than MEGAN 6 CE, especially less abundant species.

  bovine simulated cami datasets read host-sequence metagenome

• The genome sequence of the Portuguese Dappled White, Euchloe tagis (Hübner, 1804) (Lepidoptera: Pieridae).

  PMID 42028159 · PMC13100615 · Wellcome open research · 2026 · 7 claims · 8 setups

  Full-text index only

  A chromosome-level genome assembly was generated for Euchloe tagis (Portuguese Dappled White) as part of Project Psyche

  euchloe pacbio hi-c k-mer

• Onto-Tools: new additions and improvements in 2006.

  PMID 17584796 · PMC1933142 · Nucleic acids research · 2007 · 8 claims · 3 setups

  Full-text index only

  OE2GO enables functional profiling for organisms lacking public-domain annotations by allowing users to supply custom GO-format annotation files and OBO-format ontology files

  specified pathway functional example

• Genome of the Asian longhorned beetle (Anoplophora glabripennis), a globally significant invasive species, reveals key functional and evolutionary innovations at the beetle-plant interface.

  PMID 27832824 · PMC5105290 · Genome biology · 2016 · 8 claims · 7 setups

  Has reproduction · 84

  The A. glabripennis genome encodes a uniquely diverse arsenal of enzymes that degrade plant cell wall polysaccharide networks (cellulose, hemicellulose, pectin) and detoxify plant allelochemicals.

  single glabripennis amino whole-genome gene busco

• The genome sequence of the Northern Grizzled Skipper, Pyrgus centaureae (Rambur, 1839) (Lepidoptera: Hesperiidae).

  PMID 42038589 · PMC13109703 · Wellcome open research · 2026 · 8 claims · 8 setups

  Full-text index only

  A chromosome-level genome assembly was produced for Pyrgus centaureae (Northern Grizzled Skipper) as part of Project Psyche.

  pyrgus pacbio hi-c rna-seq

• nf-core/circrna: a portable workflow for the quantification, miRNA target prediction and differential expression analysis of circular RNAs.

  PMID 36694127 · PMC9875403 · BMC bioinformatics · 2023 · 8 claims · 4 setups

  Has reproduction · 76

  Existing circRNA workflows are limited: none delineate circRNA-miRNA interactions and only one performs differential expression analysis, requiring users to supplement missing analysis types with in-house expertise

  paired-end rna-seq mature circrna read circrna mirna

• BRENDA, AMENDA and FRENDA: the enzyme information system in 2007.

  PMID 17202167 · PMC1899097 · Nucleic acids research · 2007 · 7 claims · 6 setups

  Full-text index only

  BRENDA is the largest publicly available enzyme information system worldwide, manually curated from primary literature and covering all identified enzymes regardless of source.

  pubmed randomly enzyme full text-mining manual transmembrane