Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• pSTIING: a 'systems' approach towards integrating signalling pathways, interaction and transcriptional regulatory networks in inflammation and cancer.

  PMID 16381926 · PMC1347407 · Nucleic acids research · 2006 · 8 claims · 3 setups

  Full-text index only

  pSTIING is a publicly accessible web-based knowledgebase integrating protein-protein, protein-lipid, protein-small molecule interactions, transcriptional regulatory associations, ligand-receptor-cell type information, and signal transduction modules, with a focus on inflammation, cell migration and cancer.

  model gene molecular sequence clustering literature

• nf-core/isoseq: simple gene and isoform annotation with PacBio Iso-Seq long-read sequencing.

  PMID 36961337 · PMC10199315 · Bioinformatics (Oxford, England) · 2023 · 7 claims · 4 setups

  Has reproduction · 88

  nf-core/isoseq is a new automated Nextflow-based pipeline that processes raw Iso-Seq subreads through to genome annotation (BED format) without requiring transcriptome assembly.

  organism-specific iso-seq reference mapped pacbio subread long-read

• Proteomics data repositories.

  PMID 19795424 · PMC2908408 · Proteomics · 2009 · 5 claims · 5 setups

  Full-text index only

  The YRC Public Data Repository (YRC PDR) provides a single unified interface disseminating multi-technology proteomics data (mass spectrometry, yeast two-hybrid, fluorescence microscopy, structure prediction) linked to protein annotations from many source databases.

  multi-organism yeast proteomes cerevisiae tandem yeast fluorescence

• The genome sequence of the leafhopper, Arthaldeus pascuellus (Fallén, 1826) (Hemiptera: Cicadellidae).

  PMID 41625988 · PMC12859417 · Wellcome open research · 2026 · 6 claims · 8 setups

  Full-text index only

  A chromosome-level genome assembly was generated for Arthaldeus pascuellus, the first high-quality genome for the genus Arthaldeus

  organism pacbio assembled alternate pacbio hi-c barcoding

• The genome sequence of the Provence Hairstreak, Tomares ballus (Fabricius, 1787) (Lepidoptera: Lycaenidae).

  PMID 41710119 · PMC12910201 · Wellcome open research · 2026 · 7 claims · 8 setups

  Full-text index only

  A genome assembly was produced for a male Tomares ballus specimen consisting of two haplotypes (839.94 Mb and 831.10 Mb)

  organism pacbio assembled pacbio hi-c k-mer

• The genome sequence of the Spanish Festoon, Zerynthia rumina (Linnaeus, 1758) (Lepidoptera: Papilionidae).

  PMID 41769331 · PMC12946699 · Wellcome open research · 2026 · 8 claims · 7 setups

  Full-text index only

  A genome assembly for Zerynthia rumina was produced, containing two haplotypes of 852.84 Mb and 775.60 Mb

  organism genomic assembled haplotype pacbio hi-c k-mer

• SEAseq: a portable and cloud-based chromatin occupancy analysis suite.

  PMID 35193506 · PMC8864840 · BMC bioinformatics · 2022 · 7 claims · 2 setups

  Has reproduction · 94

  SEAseq is a comprehensive, infrastructure-independent pipeline that performs the major analyses needed to process ChIP-Seq/CUT&RUN chromatin binding datasets in a single execution

  any chip-seq cut&run

• Analysis of the genome of the New Zealand giant collembolan (Holacanthella duospinosa) sheds light on hexapod evolution.

  PMID 29041914 · PMC5644144 · BMC genomics · 2017 · 8 claims · 8 setups

  Has reproduction · 72

  Phylogenomic analysis (370,877 amino acids) placed H. duospinosa within the family Neanuridae

  holacanthella duospinosa genome transcriptome phylogenomics

• The genome of the ant Tetramorium bicarinatum reveals a tandem organization of venom peptides genes allowing the prediction of their regulatory and evolutionary profiles.

  PMID 38245722 · PMC10800049 · BMC genomics · 2024 · 8 claims · 8 setups

  Has reproduction · 100

  44 venom peptide genes were identified, distributed across four of the eleven chromosomes and organized in tandem repeat clusters.

  tetramorium bicarinatum vpg venom whole-genome blast gene

• Information-based methods for predicting gene function from systematic gene knock-downs.

  PMID 18959798 · PMC2596148 · BMC bioinformatics · 2008 · 8 claims · 4 setups

  Full-text index only

  Information-based metrics, which incorporate a phenotype's genomic frequency, outperform non-information-based metrics for detecting gene-gene functional similarity from phenotypic knock-down profiles.

  caenorhabditis elegans saccharomyces interference computational genome-wide

• Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology.

  PMID 18618001 · PMC2442223 · PLoS genetics · 2008 · 8 claims · 6 setups

  Full-text index only

  Zebrafish whole-adult-organism chemogenomics generates robust prediction models that discriminate P(H)AHs from ECs across independent experiments

  zebrafish computational seven consolidated whole-adult-organism supervised quantitative

• The genome sequence of the Chalk Yellow-face Bee, Hylaeus dilatatus (Kirby, 1802) (Hymenoptera: Colletidae).

  PMID 41657665 · PMC12881847 · Wellcome open research · 2026 · 8 claims · 8 setups

  Full-text index only

  A two-haplotype genome assembly of Hylaeus dilatatus was produced, with total lengths of 307.38 Mb (haplotype 1) and 314.32 Mb (haplotype 2)

  hylaeus pacbio assembled barcoding pacbio hi-c

• 2Pipe starts with a question: matching you with the correct pipeline for MAG reconstruction.

  PMID 41609375 · PMC12915991 · mSystems · 2026 · 8 claims · 1 setups

  Full-text index only

  Pipeline selection for MAG reconstruction is a nontrivial decision that must align user needs with workflow factors such as sequencing data type, analytical functions, and computational environment.

  metagenomic computational

• SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses.

  PMID 33932985 · PMC8088074 · BMC bioinformatics · 2021 · 8 claims · 5 setups

  Has reproduction · 65

  SPEAQeasy is a portable, easy-to-install, Nextflow-powered RNA-seq processing pipeline that lowers the computational entry barrier for biologists/clinicians

  provided amygdala rna-seq differentially pipeline bulk rna-based

• PA-GOSUB: a searchable database of model organism protein sequences with their predicted Gene Ontology molecular function and subcellular localization.

  PMID 15608166 · PMC540074 · Nucleic acids research · 2005 · 7 claims · 4 setups

  Full-text index only

  PA-GOSUB significantly extends the coverage of GO molecular function and subcellular localization annotations for 10 model organism proteomes compared with existing databases (GOA, Swiss-Prot).

  sequences query swiss-prot naive-bayes blast feature

• A chromosome-level genome assembly provides insights into the environmental adaptability and outbreaks of Chlorops oryzae.

  PMID 36028584 · PMC9418232 · Communications biology · 2022 · 8 claims · 8 setups

  Has reproduction · 80

  A high-quality chromosome-level genome assembly of C. oryzae was generated using PacBio, Illumina, and Hi-C sequencing

  oryzae whole-genome genome orthology

• Systematic and computational identification of Androctonus crassicauda long non-coding RNAs.

  PMID 33633149 · PMC7907363 · Scientific reports · 2021 · 8 claims · 6 setups

  Has reproduction · 71

  13,401 lncRNAs were identified in the A. crassicauda transcriptome using the ECF pipeline

  crassicauda rna-seq coding sequence

• The genome sequence of the cryptorhynchine weevil, Kyklioacalles roboris (Stüben, 2003) (Coleoptera: Curculionidae).

  PMID 41696497 · PMC12895102 · Wellcome open research · 2026 · 7 claims · 8 setups

  Full-text index only

  A chromosome-level genome assembly was produced for the cryptorhynchine weevil Kyklioacalles roboris

  kyklioacalles pacbio hi-c k-mer

• The genome sequence of the soldier beetle, Malthodes minimus (Linnaeus, 1758) (Coleoptera: Cantharidae).

  PMID 41769330 · PMC12949377 · Wellcome open research · 2026 · 8 claims · 8 setups

  Full-text index only

  The Malthodes minimus genome assembly has a total length of 583.60 Mb, with 97.75% scaffolded into 7 chromosomal pseudomolecules including X and Y sex chromosomes

  malthodes pacbio assembled alternate pacbio hi-c barcoding

• CapsID: a web-based tool for developing parsimonious sets of CAPS molecular markers for genotyping.

  PMID 16686952 · PMC1471797 · BMC genetics · 2006 · 7 claims · 1 setups

  Full-text index only

  CapsID identifies snip-SNPs (SNPs that alter restriction endonuclease recognition sites) within reference sequence alignments and designs PCR primers around them

  sequence restriction