Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
Methods for proteomic analysis of transcription factors.
PMID 19726046 · PMC2778203 · Journal of chromatography. A · 2009 · 8 claims · 8 setups
Systematic oligonucleotide 'trapping' at nM DNA concentrations allows purification of TF-RE complexes in a highly purified state, exploiting the high specific affinity vs. low non-specific affinity of TFs for DNA
-
Full-text index only
Strategies for folding of affinity tagged proteins using GroEL and osmolytes.
PMID 19082872 · PMC3693453 · Journal of structural and functional genomics · 2009 · 8 claims · 8 setups
GroEL/osmolyte mixtures can be used to refold difficult-to-fold chimeric affinity-tagged proteins by exploiting intrinsic chaperonin binding.
-
Full-text index only
Sequence-non-specific effects of RNA interference triggers and microRNA regulators.
PMID 19843612 · PMC2800214 · Nucleic acids research · 2010 · 8 claims · 7 setups
Reagents of RNAi and miRNA technologies often trigger unintended sequence-non-specific immune responses in addition to intended sequence-specific silencing
-
Full-text index only
Induction of calcification by serum depletion in cell culture: a model for focal calcification in aortas related to atherosclerosis.
PMID 18230165 · PMC2248577 · Lipids in health and disease · 2008 · 8 claims · 8 setups
Serum depletion induces calcification (mineral Ca/P deposition) in rabbit aortic smooth muscle cell culture
-
Full-text index only
Proteomic analysis of differentially expressed proteins in hepatitis B virus-related hepatocellular carcinoma tissues.
PMID 19715608 · PMC2743659 · Journal of experimental & clinical cancer research : CR · 2009 · 8 claims · 5 setups
17 differentially expressed proteins were identified between HBV-related HCC tissue and adjacent non-tumorous liver tissue by 2-DE/MALDI-TOF-MS
-
Has reproduction · 83
Cold-Induced Lipoprotein Clearance in Cyp7b1-Deficient Mice.
PMID 35478959 · PMC9038073 · Frontiers in cell and developmental biology · 2022 · 7 claims · 8 setups
Cyp7b1 deficiency blunts cold-induced hepatic Cyp7b1 upregulation and plasma bile acid synthesis
-
Has reproduction · 74
L-Arabinose Alters the E. coli Transcriptome to Favor Biofilm Growth and Enhances Survival During Fluoroquinolone Stress.
PMID 40732174 · PMC12299780 · Microorganisms · 2025 · 8 claims · 6 setups
L-arabinose increases planktonic growth rate but reduces total growth of E. coli at both 28°C and 37°C
-
Full-text index only
Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach.
PMID 17010196 · PMC1592491 · BMC genomics · 2006 · 8 claims · 7 setups
High-throughput 454 sequencing-by-synthesis of LNCaP cDNA can profile transcript abundance across the transcriptome
-
Full-text index only
Three assays show differences in binding of wild-type and mutant p53 to unique gene sequences.
PMID 19925028 · PMC2917581 · Technology in cancer research & treatment · 2009 · 7 claims · 6 setups
Three different DNA binding assays (EMSA, SPA, streptavidin magnetic bead assay) show differences in binding of wild-type and mutant p53 to unique gene sequences