Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist.
PMID 18795106 · PMC2532782 · Experimental diabetes research · 2008 · 6 claims · 4 setups
GeneSpeed Beta Cell is an online genomics data repository allowing simultaneous multiexperiment viewing and multidimensional (Boolean intersection/union) querying of pancreas- and islet-relevant datasets, integrated with GeneSpeed's domain-based gene categorization.
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Has reproduction · 88
Age Deceleration and Reversal Gene Patterns in Dauer Diapause.
PMID 41104926 · PMC12686545 · Aging cell · 2025 · 8 claims · 8 setups
Dauer arrest, regardless of duration, does not cause lasting functional decline in lifespan, brood size, or developmental resumption
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Neonatal salivary analysis reveals global developmental gene expression changes in the premature infant.
PMID 19959617 · PMC2853178 · Clinical chemistry · 2010 · 7 claims · 6 setups
Salivary genomic microarray analysis reveals global developmental gene expression changes in premature infants over postnatal age
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Has reproduction · 67
Unraveling the timeline of gene expression: A pseudotemporal trajectory analysis of single-cell RNA sequencing data.
PMID 37994351 · PMC10663991 · F1000Research · 2023 · 7 claims · 7 setups
A reproducible R-based workflow combines Seurat (QC, clustering, integration), monocle3 (trajectory inference), and edgeR (pseudo-bulk time course analysis) to perform single-cell pseudotemporal time course analysis.
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Has reproduction · 83
Gene Expression Atlas update--a value-added database of microarray and sequencing-based functional genomics experiments.
PMID 22064864 · PMC3245177 · Nucleic acids research · 2012 · 8 claims · 5 setups
Gene Expression Atlas is an added-value database providing curated, re-annotated and statistically analysed gene expression data across cell types, organism parts, developmental stages, disease states and other biological/experimental conditions, derived from ArrayExpress Archive and the European Nucleotide Archive.
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Has reproduction · 76
Daily temperature cycles promote alternative splicing of RNAs encoding SR45a, a splicing regulator in maize.
PMID 33705553 · PMC8195531 · Plant physiology · 2021 · 8 claims · 4 setups
Increasing maximum daily temperature (MDT) globally elevates the frequency of alternative splicing in maize, particularly intron retention and exon skipping.
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Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation.
PMID 17704778 · PMC2872770 · Nature genetics · 2007 · 8 claims · 6 setups
Mutations in UPF3B cause syndromic (Lujan-Fryns syndrome, FG syndrome) and nonsyndromic X-linked mental retardation
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The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis.
PMID 18452600 · PMC2396169 · BMC evolutionary biology · 2008 · 8 claims · 5 setups
169 gene products in the Ciona genome were identified as putative GPCRs
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Has reproduction · 50
Ancient gene duplicates in Gossypium (cotton) exhibit near-complete expression divergence.
PMID 24558256 · PMC3971588 · Genome biology and evolution · 2014 · 8 claims · 8 setups
Nearly all (99.4%) ancient paralog pairs in Gossypium raimondii are differentially expressed in at least one of three tissues (petal, leaf, seed), indicating massive, near-complete expression-level divergence.
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Has reproduction
Empowering integrative and collaborative exploration of single-cell and spatial multimodal data with SGS genome browser.
PMID 40233745 · PMC12143324 · Cell genomics · 2025 · 8 claims · 6 setups
SGS is a user-friendly, collaborative, versatile browser for integrative visualization of single-cell and spatial multimodal (scMulti-omics) data
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Has reproduction · 60
Core transcriptional signatures of phase change in the migratory locust.
PMID 31292921 · PMC6881432 · Protein & cell · 2019 · 8 claims · 7 setups
PhaseCore genes defined by AC-PCA contribution to phase differentiation predict phase status with >87.5% accuracy
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Has reproduction · 59
Comparing time series transcriptome data between plants using a network module finding algorithm.
PMID 31164912 · PMC6544932 · Plant methods · 2019 · 8 claims · 6 setups
Converting time-series expression data into co-expression networks and applying network module finding (OrthoClust) enables cross-species comparison without requiring one-to-one developmental stage mapping.
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Has reproduction · 56
Identification of key genes in chickpea transcriptomics and the development of ChickpeaOmicsR as a comprehensive resource to advance breeding and genomic studies.
PMID 41909810 · PMC13022592 · Frontiers in bioinformatics · 2026 · 8 claims · 4 setups
ChickpeaOmicsR is the first comprehensive/specialized R package integrating transcriptomic, genomic, and proteomic (RNA-seq, GWAS, PPI) data within a unified, reproducible framework and standardizing fragmented chickpea gene nomenclature.
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Has reproduction · 57
Diapause vs. reproductive programs: transcriptional phenotypes in a keystone copepod.
PMID 33782539 · PMC8007741 · Communications biology · 2021 · 8 claims · 7 setups
t-SNE clustering of all-gene expression data groups field-collected (diapause program) samples into one cluster while early and late culture (reproductive program) samples separate into two distinct phenotypes
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Microarray analysis: genome-scale hypothesis scanning.
PMID 14551912 · PMC212694 · PLoS biology · 2003 · 8 claims · 5 setups
Microarrays can be used to both test and generate hypotheses, not merely to fish for candidate genes.
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A new family of giardial cysteine-rich non-VSP protein genes and a novel cyst protein.
PMID 17183673 · PMC1762436 · PloS one · 2006 · 8 claims · 7 setups
HCNCp is a novel invariant (non-variant) cyst protein belonging to a new family of high-cysteine membrane proteins (HCMp) abundant in the Giardia genome
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Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates.
PMID 16818254 · PMC1874166 · Environmental health perspectives · 2006 · 8 claims · 8 setups
Estrogen-responsive genes in mouse uterus are induced in a dose-dependent, ER-α-dependent manner, as shown by loss of induction in ER-α knockout mice.
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Genomic expression during human myelopoiesis.
PMID 17683550 · PMC2045681 · BMC genomics · 2007 · 8 claims · 5 setups
An integrated myelopoiesis expression dataset of 9,425 genes, each mapped to a unique genomic position, was generated from 24 microarray experiments across 8 myeloid cell types.
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Have microarrays failed to deliver for developmental biology?
PMID 12225576 · PMC139405 · Genome biology · 2002 · 8 claims · 8 setups
Despite predictions that microarrays would transform biology, very few published developmental biology microarray studies have generated novel insights.
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Has reproduction · 78
Identification of the Wheat (Triticum aestivum) IQD Gene Family and an Expression Analysis of Candidate Genes Associated with Seed Dormancy and Germination.
PMID 35456910 · PMC9025732 · International journal of molecular sciences · 2022 · 8 claims · 8 setups
73 IQD gene family members (TaIQD1-73) were identified in the wheat genome and phylogenetically divided into six major groups.