Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 100
Complete human day 14 post-implantation embryo models from naive ES cells.
PMID 37673118 · PMC10584686 · Nature · 2023 · 8 claims · 8 setups
Genetically unmodified human naive ES cells can self-assemble into complete SEMs recapitulating nearly all post-implantation human embryo lineages (epiblast, hypoblast, extra-embryonic mesoderm, trophoblast).
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Has reproduction · 50
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
PMID 36696508 · PMC9876548 · Science advances · 2023 · 7 claims · 8 setups
Chromatin accessibility continually decreases from mitotic entry until metaphase, then gradually increases as chromosomes segregate.
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Has reproduction · 37
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8(+) T cells.
PMID 37081150 · PMC10154250 · Nature immunology · 2023 · 8 claims · 6 setups
Orthogonal engineering of CD8+ T cells to co-secrete IL-2v and IL-33 (with PD-1 decoy) drives a novel synthetic effector state (C5 T_SE) that deviates from canonical PD-1+TOX+ exhaustion.
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Has reproduction · 75
Single-cell dissection of chronic lung allograft dysfunction reveals convergent and distinct fibrotic mechanisms.
PMID 41122970 · PMC12581678 · JCI insight · 2025 · 8 claims · 7 setups
CLAD harbors disease-specific cellular subsets including Fibro.AT2 cells, exhausted CD8+ T cells, and superactivated macrophages